DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt303B3 and Ugt36F1

DIOPT Version :9

Sequence 1:	NP_651152.1	Gene:	Ugt303B3 / 42774	FlyBaseID:	FBgn0039085	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster

Alignment Length:	567	Identity:	156/567 - (27%)
Similarity:	270/567 - (47%)	Gaps:	82/567 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LAVLFCLFLQKDLYQDSVQAANILGIFSYHFSSHNLVVRPLAKALVKRGHNVTLIT------PVG 66
            ||:|  .||.:....|   ||:|||:|.:...||....||:..||.:||||:::.:      ||.
  Fly     6 LALL--AFLLRPKPND---AAHILGLFQHPGKSHFDFFRPMFLALAERGHNISMYSYFPLEKPVA 65

  Fly    67 MPTD--IEGVRHIRVPKLNQRVQEMIEGDQILDFFGSKWIA-----SLMVVSMLYN---MSSDIL 121
            ..||  .:|     :|.|...|.        |..|.|:|..     .:....||::   .|..:.
  Fly    66 NYTDYVFQG-----MPLLTDIVD--------LSNFESEWKPLGLPFKVPTYFMLHDWGLRSCKVA 117

  Fly   122 SDKGVQKMLQNRNERFDLVMLEPSALEALYGVVEHYNATLMGFSG-GNVNWSTEEVAGNFAPSIN 185
            .:..:...|.....|:|:::||..:.:.:..|....||.::..|. ..:.|..:.:.   :|.||
  Fly   118 LNSPLITQLLKSPIRYDVILLEHFSNDCMAAVAHLLNAPVIALSSCAIMPWHYKRMG---SPFIN 179

  Fly   186 D--PISSLGYSRSNSLLSKIYNWVHITEEKLLKHLIFRPSQLRIFKKFFNFSEQKFYNMREKYSV 248
            .  |::.|.|:...||:.::.|:.|......|.::|.:|:...:..:.|.........:.:..|:
  Fly   180 PIMPMNFLPYTDEMSLIDRLNNFFHFHTVNTLYNMITQPATDALIAERFGPGLPPINEIVKNTSL 244

  Fly   249 ILVNNHISMGRVRSNVPNIIEVGGLHLTEPAEPCDSKLQKFMDDAEHGVIYFSMGQEIMVQFLPE 313
            :|:|.|.::...|...||:||||||.: .|.:|....|...:|.:.:||||.|.|..:....||.
  Fly   245 MLINQHYALTGPRPYAPNVIEVGGLQV-GPIKPLPQHLLDLLDRSPNGVIYISWGSMVNSNTLPS 308

  Fly   314 DMQQNLMKSLDQFKQR---VVWKTELYNMPNKS-DNVYVIEQPPQRAVLAHPNTRLFITNGGLLS 374
            ..:..|.:|:.|.|:.   :.||: |.::.:|. .|:|..:..|||.:|.||..|.||::||||.
  Fly   309 GKRSALFQSISQLKEYNFVMRWKS-LESLEDKQPSNLYTFDWLPQRDLLCHPKIRAFISHGGLLG 372

  Fly   375 VMEAVYSGVPILGLPVFFDQFINLRNVNLRGMAEVLDANEMTLEILTSTIRKLLENPRYALKAKK 439
            ..||::.|||:|..|.:.|||:|...|..||...::|..:.....:|..:|.:|:. ::|.:.::
  Fly   373 TTEAIHCGVPMLVTPFYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRGLRIILDK-KFAERVRR 436

  Fly   440 MSQSFRDRPMSPLDTAVWWTEYALRNKDASHMR----------LNTEDVPLYYEWDWGLLLGLRF 494
            .|::||.||:.|:..|.||.|:.::...|.|::          .|:.||.|::           .
  Fly   437 SSEAFRQRPIPPIKLATWWIEHVIKYGGAPHIQSEARHINWIVYNSIDVLLFW-----------L 490

  Fly   495 GIVFGSVIYL--VYKLFQKTSARRRPFQVTGTVSQHPSLLDRRSQTQ 539
            ||:|..::.|  :.|:|:....|       |.:|:     |.:::||
  Fly   491 GILFLLIVALRKLIKIFKTAFCR-------GKISR-----DTKTKTQ 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B3	NP_651152.1	egt	7..466	CDD:223071	138/480 (29%)
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	138/489 (28%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	124/441 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454645
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	9	8.890