DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt303B3 and Ugt301D1

DIOPT Version :9

Sequence 1:	NP_651152.1	Gene:	Ugt303B3 / 42774	FlyBaseID:	FBgn0039085	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_001246079.1	Gene:	Ugt301D1 / 35105	FlyBaseID:	FBgn0032684	Length:	530	Species:	Drosophila melanogaster

Alignment Length:	505	Identity:	142/505 - (28%)
Similarity:	257/505 - (50%)	Gaps:	41/505 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 ANILGIFSYHFSSHNLVVRPLAKALVKRGHNVTLIT--PVGMP----TDIEGVRHIRVPKLNQRV 86
            :.||.:..:...||.|.:......|:::||:||.:.  |...|    |:|.......:||  ...
  Fly    25 SRILFMGPFPAPSHWLWLEHFQNDLLRQGHHVTSVNNHPTKHPHENLTEIIISPSFDIPK--HFP 87

  Fly    87 QEMIEGDQILDFFGSK---WIASLMVVSMLYNMSSDILSDKGVQKMLQNRNERFDLVMLEPSALE 148
            :|.|...|.:..|.:.   |...||.....:       .|..|:|:::::::.:|||::|....|
  Fly    88 KENIFSMQFVSDFNNLELWWTIGLMTTEHAF-------KDPKVKKLIESKDDHYDLVIIEQFFHE 145

  Fly   149 ALYGVVEHYNATL-----MGFSGGNVNWSTEEVAGNFAPSINDPISSLGYSRSNSLLSKIYNWVH 208
            |.....:.:|..:     ||::.     :.:...|...|....|...|.::...:...:.||...
  Fly   146 AFLMFGKRFNCPVVTIGTMGYAD-----NIDHAMGILTPWSLIPHLLLSHTDRMTFGQRAYNAYL 205

  Fly   209 ITEEKLLKHLIFRPSQLRIFKKFFNFSEQ----KFYNMREKYSVILVNNHISMGRVRSNVPNIIE 269
            ...:.:::..::.|...::.:|:|..|.:    ...::....|::|:|.|.|:...|.::|.:|:
  Fly   206 SLYDAVMRRWVYLPKMQKLAEKYFQGSIEGPLPNVLDLERNISLVLINAHRSIDLPRPSMPGLID 270

  Fly   270 VGGLHLTEPAE-PCDSKLQKFMDDAEHGVIYFSMGQEIMVQFLPEDMQQNLMKSLDQFKQRVVWK 333
            |||.|:.:|.: |.|  ||.|:|:|.:||||||||..:....||::....::|:..|.||:|:||
  Fly   271 VGGAHIQKPKQLPTD--LQNFLDNATYGVIYFSMGSYVKSTDLPQEKTALILKAFGQLKQQVIWK 333

  Fly   334 TELYNMPNKSDNVYVIEQPPQRAVLAHPNTRLFITNGGLLSVMEAVYSGVPILGLPVFFDQFINL 398
            .|..::.:...||.:.:..||..:|||||.:||||:||:....|.:|.|||:|.:|::.||..|.
  Fly   334 FENDSIGDLPSNVMIKKWMPQNDILAHPNVKLFITHGGIFGTQEGIYWGVPMLCVPLYGDQHRNT 398

  Fly   399 RNVNLRGMAEVLDANEMTLEILTSTIRKLLENPRYALKAKKMSQSFRDRPMSPLDTAVWWTEYAL 463
            ......|.|..|..:::|.:.|...|..|:.:|:|...|.::||.|||.|:.|||.|.:|.||.:
  Fly   399 IKSVREGYARSLVFSKLTTDDLVRNIETLINDPQYKRSALEVSQRFRDNPIHPLDEATFWIEYII 463

  Fly   464 RNKDASHMRLNTEDVPLYYEWDWGLLLGLRFGIVFGS--VIYLVYKLFQK 511
            |::.|.|::.:...:||:..    |||.:...::.|:  .|:|.:::.::
  Fly   464 RHRGARHLKSHGAFIPLHQY----LLLDVLGCLLLGAFLAIWLPWRMIRR 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B3	NP_651152.1	egt	7..466	CDD:223071	132/456 (29%)
Ugt301D1	NP_001246079.1	egt	12..483	CDD:223071	136/473 (29%)
Ugt301D1	NP_001246079.1	UDPGT	37..483	CDD:278624	134/461 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	1	0.900	-	-		E33208_3BDT1
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	9	8.860