Protein Alignment Ugt303B3 and Ugt2a3

DIOPT Version :10

• Sequence 1: NP_651152.1
• Gene: Ugt303B3 / 42774
• FlyBaseID: FBgn0039085
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_001129341.1
• Gene: Ugt2a3 / 289533
• RGDID: 1308444
• Length: 534
• Species: Rattus norvegicus
• Alignment Length: 509
• Identity: 135/509 - (26%)
• Similarity: 229/509 - (44%)
• Gaps: 102/509 - (20%)

  Fly    40 SHNLVVRPLAKALVKRGHNVTLI-------------------TPVGMPTDIEGVRHIR------- 78
            ||.|.::.:.:.|..|||.||::                   .||...|:: ...|:.
  Rat    34 SHWLNLKTILEELAARGHEVTVLKYPSIIIDQSKLTPLQFENIPVLYETEV-AENHLNEIVNLAV 97

  Fly    79 --VPKLNQRVQEMIEGDQIL-DFFGSKWIASLMVVSMLYNMSSDILSDKGVQKMLQNRNERFDLV 140
              :|.|:     :.|..:.| |||       |.:.....::....|.::.:...|  |:.::|::
  Rat    98 NVIPNLS-----LWEAARTLQDFF-------LQLTGNFEDLCRSTLYNQTLMNKL--RDAKYDVM 148

  Fly   141 MLEP--SALEALYGVVEHYNATLMGFSGGNVNWSTEEVAGNFAPSINDPISSLGYSRSN--SLLS 201
            :|:|  ...|.:..|::                         .|.:|....|:|||...  ..|.
  Rat   149 VLDPVIPCGELVAEVLQ-------------------------IPFVNTLRFSMGYSMEKYCGQLP 188

  Fly   202 KIYNWVHITEEKLLKHLIF----RPSQLRIFKKF------FNFSEQKFYNMR-----------EK 245
            ...::|.:...:|..|:.|    :...|.:|.:|      |.|.:| ||:..           .|
  Rat   189 VPLSYVPVVMGELTDHMTFTERVKNMMLSLFFEFWLQQYDFAFWDQ-FYSKTLGRPTTFCKTVGK 252

  Fly   246 YSVILVNNHISMGRVRSNVPNIIEVGGLHLTEPAEPCDSKLQKFMDDA-EHGVIYFSMGQEIMVQ 309
            ..:.|:..:..:...|..:||...||||| .:||:|...:|::|:..: ||||:.||:|.  |::
  Rat   253 AEIWLIRTYWDIEFPRPYLPNFEFVGGLH-CKPAKPLPKELEEFVQSSGEHGVVVFSLGS--MIK 314

  Fly   310 FLPEDMQQNLMKSLDQFKQRVVWKTELYNMPNKSDNVYVIEQPPQRAVLAHPNTRLFITNGGLLS 374
            .|.|:....:..:|.|..|:|:|:...........|..::...||..:|.||.||.|||:||...
  Rat   315 NLTEEKANLIASALAQIPQKVLWRYSGKKPATLGPNTRILNWIPQNDLLGHPKTRAFITHGGTNG 379

  Fly   375 VMEAVYSGVPILGLPVFFDQFINLRNVNLRGMAEVLDANEMTLEILTSTIRKLLENPRYALKAKK 439
            :.||:|.|||::|:|:|.||..|:.::..:|.|..:..|.||...|.|.:|.::..|.|...|.:
  Rat   380 IYEAIYHGVPMVGIPMFGDQPYNIAHMEAKGAAVKVAINTMTSADLLSALRAVINEPSYKENAMR 444

  Fly   440 MSQSFRDRPMSPLDTAVWWTEYALRNKDASHMRLNTEDVP--LYYEWD-WGLLL 490
            :|:...|:|:.|||.||:|.|:.:|:|.|.|:|:...|:.  .|:..| .|.||
  Rat   445 LSRVHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFLL 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B3	NP_651152.1	GT1_Gtf-like	28..458	CDD:340817	122/472 (26%)
Ugt2a3	NP_001129341.1	UDPGT	25..519	CDD:278624	135/509 (27%)