Protein Alignment Ugt303B3 and Ugt2b1

DIOPT Version :10

• Sequence 1: NP_651152.1
• Gene: Ugt303B3 / 42774
• FlyBaseID: FBgn0039085
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_775417.1
• Gene: Ugt2b1 / 286954
• RGDID: 708541
• Length: 529
• Species: Rattus norvegicus
• Alignment Length: 522
• Identity: 133/522 - (25%)
• Similarity: 241/522 - (46%)
• Gaps: 82/522 - (15%)

  Fly    40 SHNLVVRPLAKALVKRGHNVTLITPVGM----PTDIEGVRHIRVPKLNQRVQEMIEGDQILDFFG 100
            ||.:.::.:...|.:|||.||::.....    ||        :...:|..:..:......|::..
  Rat    34 SHWINIKIILNELAQRGHEVTVLVSSASILIEPT--------KESSINFEIYSVPLSKSDLEYSF 90

  Fly   101 SKWI-------ASLMV------VSMLYNMSSDILS--------DKGVQKMLQNRNERFDLVMLE- 143
            :|||       .:|.:      :..::|..||::.        :|.:.|.||  ..:||:::.:
  Rat    91 AKWIDEWTRDFETLSIWTYYSKMQKVFNEYSDVVENLCKALIWNKSLMKKLQ--GSQFDVILADA 153

  Fly   144 --PSALEALYGVVEHYNATLMGFSGGNVNWSTEEVAG------NFAPSINDPISS--LGYSRSNS 198
              |.. |.|..:::......:.|..|   :..|:.:|      ::.|.:...:|.  ....|..:
  Rat   154 VGPCG-ELLAELLKTPLVYSLRFCPG---YRCEKFSGGLPLPPSYVPVVLSELSDRMTFVERVKN 214

  Fly   199 LLSKIY--NWVHITEEK----LLKHLIFRPSQLRIFKKFFNFSEQKFYNMREKYSVILVNNHISM 257
            :|..:|  .|....:||    ....::.||:.|.              .|..|..:.|:.....:
  Rat   215 MLQMLYFDFWFQPFKEKSWSQFYSDVLGRPTTLT--------------EMMGKADIWLIRTFWDL 265

  Fly   258 GRVRSNVPNIIEVGGLHLTEPAEPCDSKLQKFMDDA-EHGVIYFSMGQEIMVQFLPEDMQQNLMK 321
            ......:||...||||| .:||:|...::::|:..: ||||:.||:|.  ||:.|.|:....:..
  Rat   266 EFPHPFLPNFDFVGGLH-CKPAKPLPREMEEFVQSSGEHGVVVFSLGS--MVKNLTEEKANVVAS 327

  Fly   322 SLDQFKQRVVWKTELYNMPNKSDNVYVIEQPPQRAVLAHPNTRLFITNGGLLSVMEAVYSGVPIL 386
            :|.|..|:|||:.:.........|..:.:..||..:|.||.|:.|:.:||...:.||:|.|:||:
  Rat   328 ALAQIPQKVVWRFDGKKPDTLGSNTRLYKWIPQNDLLGHPKTKAFVAHGGTNGIYEAIYHGIPIV 392

  Fly   387 GLPVFFDQFINLRNVNLRGMAEVLDANEMTLEILTSTIRKLLENPRYALKAKKMSQSFRDRPMSP 451
            |:|:|.||..|:.::..:|.|..:|.:.::...|.:.::.::.:|.|...|.::|:...|:|:.|
  Rat   393 GIPLFADQPDNINHMVAKGAAVRVDFSILSTTGLLTALKIVMNDPSYKENAMRLSRIHHDQPVKP 457

  Fly   452 LDTAVWWTEYALRNKDASHMRLNTEDVP--LYYEWD-WGLLLGLRFGIVFGSVIYLVYKLF--QK 511
            ||.||:|.||.:|:|.|.|:|....|:.  .|:..| .|.||....|:||   |...:.||  :|
  Rat   458 LDRAVFWIEYVMRHKGAKHLRSTLHDLSWFQYHSLDVIGFLLLCVVGVVF---IITKFCLFCCRK 519

  Fly   512 TS 513
            |:
  Rat   520 TA 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B3	NP_651152.1	GT1_Gtf-like	28..458	CDD:340817	111/460 (24%)
Ugt2b1	NP_775417.1	UDPGT	24..527	CDD:278624	133/522 (25%)