Protein Alignment Ugt303B3 and Ugt2b

DIOPT Version :10

• Sequence 1: NP_651152.1
• Gene: Ugt303B3 / 42774
• FlyBaseID: FBgn0039085
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_113721.5
• Gene: Ugt2b / 24862
• RGDID: 3936
• Length: 530
• Species: Rattus norvegicus
• Alignment Length: 568
• Identity: 138/568 - (24%)
• Similarity: 247/568 - (43%)
• Gaps: 101/568 - (17%)

  Fly     7 WLAVLFCLFLQKDLYQDSVQAANILGIFSYHFSSHNLVVRPLAKALVKRGHNVTLITPVGMPTDI 71
            |::.||  .||......|.....:| ::...| ||.:.::.:...||:|||.||::.|
  Rat     5 WISALF--LLQISYCFKSGHCGKVL-VWPMDF-SHWMNIKIILDELVQRGHEVTVLKP------- 58

  Fly    72 EGVRHIRVPKLNQRVQ-----EMIEGDQILDFF---GSKWIASL----------MVVSMLYNMS- 117
             .......||.:..::     ..|..|::.:.|   ...|...|          ::.:::|..|
  Rat    59 -SAYFFLDPKKSSDLKFEIFSTSISKDELQNHFIKLLDVWTYELPRDTCLSYSPILQNLVYEFSY 122

  Fly   118 ------SDILSDKGVQKMLQNRNERFDLVMLEPSA-----LEALYGVVEHYNATLMGFSGGNVNW 171
                  .|.:|:|  |.|.:.:..:||::..:|.|     :..|..:...|:   :.||.|:
  Rat   123 FYLSICKDAVSNK--QLMTKLQESKFDVLFADPVASCGDLIAELLHIPFLYS---LSFSPGH--- 179

  Fly   172 STEEVAGNF-APSINDPISSLGYSRSNSLLSKIYN---------WVHITEEK----LLKHLIFRP 222
            ..|:..|.| .|....|:...|.:...:.:.::.|         |..|...|    ....::.||
  Rat   180 KLEKSIGKFILPPSYVPVILSGLAGKMTFIDRVKNMICMLYFDFWFEILRHKEWDTFYSEILGRP 244

  Fly   223 SQLRIFKKFFNFSEQKFYNMREKYSVILVNNHISMGRVRSNVPNIIEVGGLHLTEPAEPCDSKLQ 287
            :.:.              ....|..:.|:.::..:......:||:..:|||| .:||:|....::
  Rat   245 TTVD--------------ETMSKVEIWLIRSYWDLKFPHPTLPNVDYIGGLH-CKPAKPLPKDME 294

  Fly   288 KFMDDA-EHGVIYFSMGQEIMVQFLPEDMQQNLMKSLDQFKQRVVWKTELYNMPNKSDNVYVIEQ 351
            :|:..: ||||:.||:|.  ||..:.|:....:..:|.|..|:|:||.:.........|..|.:.
  Rat   295 EFVQSSGEHGVVVFSLGS--MVSNMTEEKANAIAWALAQIPQKVLWKFDGKTPATLGPNTRVYKW 357

  Fly   352 PPQRAVLAHPNTRLFITNGGLLSVMEAVYSGVPILGLPVFFDQFINLRNVNLRGMAEVLDANEMT 416
            .||..:|.||.|:.|:|:||...:.||:|.|:|::|:|:|.||..|:.::..:|.|..|:...|:
  Rat   358 LPQNDILGHPKTKAFVTHGGANGLYEAIYHGIPMIGIPLFGDQPDNIAHMVAKGAAVSLNIRTMS 422

  Fly   417 LEILTSTIRKLLENPRYALKAKKMSQSFRDRPMSPLDTAVWWTEYALRNKDASHMRLNTEDVPLY 481
            .....|.:.::::||.|......:|....|:||.|||.||:|.|:.:|:|.|.|:|      ||.
  Rat   423 KLDFLSALEEVIDNPFYKKNVMLLSTIHHDQPMKPLDRAVFWIEFIMRHKGAKHLR------PLG 481

  Fly   482 YEWDW---------GLLLGLRFGIVFG---SVIYLVYKLFQKTSARRR 517
            :...|         |.||.. |.::..   ..:..:|:.|.|...:.:
  Rat   482 HNLPWYQYHSLDVIGFLLTC-FAVIAALTVKCLLFMYRFFVKKEKKMK 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B3	NP_651152.1	GT1_Gtf-like	28..458	CDD:340817	115/474 (24%)
Ugt2b	NP_113721.5	UDPGT	24..527	CDD:278624	132/544 (24%)