Protein Alignment Ugt303B3 and Ugt1a1

DIOPT Version :10

• Sequence 1: NP_651152.1
• Gene: Ugt303B3 / 42774
• FlyBaseID: FBgn0039085
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_036815.1
• Gene: Ugt1a1 / 24861
• RGDID: 3935
• Length: 535
• Species: Rattus norvegicus
• Alignment Length: 549
• Identity: 137/549 - (24%)
• Similarity: 241/549 - (43%)
• Gaps: 98/549 - (17%)

  Fly     8 LAVLFCLFLQKDLYQDSVQAANILGIFSYHF---------SSHNLVVRPLAKALVKRGHNVTLIT 63
            |.:|.||.|            .:||..:.|.         .||.|.:..:.:.|.::||.|.:|.
  Rat    11 LLLLPCLLL------------CVLGPSASHAGKLLVIPIDGSHWLSMLGVIQQLQQKGHEVVVIA 63

  Fly    64 PVGMPTDIEG----VRHIRVPKLNQRV-QEMIE-GDQILD---FFGSKWIASLMVVSMLYNM--- 116
            |.......||    :|...||..|:.| ...:| |..:.|   |        |:.|...||.
  Rat    64 PEASIHIKEGSFYTMRKYPVPFQNENVTAAFVELGRSVFDQDPF--------LLRVVKTYNKVKR 120

  Fly   117 -SSDILSDKGVQKMLQN-------RNERFDLVMLEP-----------SALEALYGVVEHYNATLM 162
             ||.:||  |...:|.|       ....||.::.:|           .:|.|:|.:
  Rat   121 DSSMLLS--GCSHLLHNAEFMASLEQSHFDALLTDPFLPCGSIVAQYLSLPAVYFL--------- 174

  Fly   163 GFSGGNVNWSTEEVAGNFAPSINDPISSLGYSRSN-----SLLSKIYNWVHITEEKLLKHLIFRP 222
                 |....:.::.....|:   |:|.:..|.|:     :.|.::.|.:....|..|..:::.|
  Rat   175 -----NALPCSLDLEATQCPA---PLSYVPKSLSSNTDRMNFLQRVKNMIIALTENFLCRVVYSP 231

  Fly   223 ---SQLRIFKKFFNFSEQKFYNMREKYSVILVNNHISMGRVRSNVPNIIEVGGLHLTEPAEPCDS 284
               ....|.:|     |....::....|:.|:.|.......|..:||::.:||::..: .:....
  Rat   232 YGSLATEILQK-----EVTVKDLLSPASIWLMRNDFVKDYPRPIMPNMVFIGGINCLQ-KKALSQ 290

  Fly   285 KLQKFMD-DAEHGVIYFSMGQEIMVQFLPEDMQQNLMKSLDQFKQRVVWKTELYNMPNKSDNVYV 348
            :.:.::: ..|||::.||:|.  ||..:||.....:.::|.:..|.|:|:.......|.:.|..:
  Rat   291 EFEAYVNASGEHGIVVFSLGS--MVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTIL 353

  Fly   349 IEQPPQRAVLAHPNTRLFITNGGLLSVMEAVYSGVPILGLPVFFDQFINLRNVNLRGMAEVLDAN 413
            ::..||..:|.||..|.|||:.|...:.|.:.:|||::.:|:|.||..|.:.:..||....|:..
  Rat   354 VKWLPQNDLLGHPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVL 418

  Fly   414 EMTLEILTSTIRKLLENPRYALKAKKMSQSFRDRPMSPLDTAVWWTEYALRNKDASHMRLNTEDV 478
            |||.:.|.:.::.::.|..|.....::|...:|||:.|||.||:|.||.:|:|.|.|:|....|:
  Rat   419 EMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDL 483

  Fly   479 PLYYEWDWGLLLGLRFGIVFGSVIYLVYK 507
             .:|::....::|....||. :|:::|||
  Rat   484 -TWYQYHSLDVIGFLLAIVL-TVVFIVYK 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B3	NP_651152.1	GT1_Gtf-like	28..458	CDD:340817	115/478 (24%)
Ugt1a1	NP_036815.1	UDPGT	30..526	CDD:278624	129/518 (25%)