DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt303B3 and Ugt3a2

DIOPT Version :9

Sequence 1:	NP_651152.1	Gene:	Ugt303B3 / 42774	FlyBaseID:	FBgn0039085	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_659094.1	Gene:	Ugt3a2 / 223337	MGIID:	2145969	Length:	523	Species:	Mus musculus

Alignment Length:	532	Identity:	143/532 - (26%)
Similarity:	248/532 - (46%)	Gaps:	63/532 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 WLAVLFCLFLQKDLYQDSVQAANILGIFSYHFSSHNLVVRPLAKALVKRGHNVT--LITPVGMPT 69
            ||.:.| |||:..|    ::||.||.| |...:||.:|:..:::.|.:.|||||  |.....:|
Mouse     7 WLLMSF-LFLEVIL----LEAAKILTI-STLSASHYIVISRVSQVLHEGGHNVTKLLYESANIP- 64

  Fly    70 DIE------GVRHIRVPK--------LNQRVQEMIEGDQILDFFG-SKWIASLMVVSMLYNMSSD 119
            |..      .|.:.|.|:        |..|:.|.|.       :| ||....|.:.....::.|.
Mouse    65 DFRKEKPSYQVINWRPPEDQEKKFADLRHRLTEEIT-------YGRSKHHTLLKIHQYFGDLCSQ 122

  Fly   120 ILSDKGVQKMLQNRNERFDLVMLEPSALEALYGVVEHYNATLMGFSGGNVNWSTEEVAGNFAPSI 184
            :||.|.:...|  :||.||||:|:...|.:|. :||......:.|.  ...:|..:.....||..
Mouse   123 LLSRKDIMDFL--KNENFDLVLLDSMDLCSLL-IVEKLGKRFVSFL--PFQFSYMDFGLPSAPLS 182

  Fly   185 NDPISSLGYSRSNSLLSKIYNWVHITEEKLLKHLIFRPSQLRIFKKFFNFSEQKFYNMREKYSVI 249
            ..|:...|.:.......::.|::...:..:.:..|.......|.:.|...|:....::..|..:.
Mouse   183 YAPVYGSGLTDQMDFWGRVKNFLMFLDFSMKQREILSQYDSTIQEHFVEGSQPVLSDLLLKAELW 247

  Fly   250 LVNNHISMGRVRSNVPNIIEVGGLHLTEPAEPCDSKLQKFMDD-AEHGVIYFSMGQEI-MVQFLP 312
            .||:..::...|...||.:.|||| |.:|.:|....|:.|:.. .:.|.:..::|..: |:|  .
Mouse   248 FVNSDFALDFARPLFPNTVYVGGL-LDKPVQPIPQDLENFISQFGDSGFVLVALGSIVSMIQ--S 309

  Fly   313 EDMQQNLMKSLDQFKQRVVWKTELYNMP---NKSDNVYVIEQPPQRAVLAHPNTRLFITNGGLLS 374
            :::.:.:..:.....|.|:|..:..:.|   :.:.||.:::..||..:||||:.|||:|:||:.|
Mouse   310 KEIIKEMNSAFAHLPQGVLWTCKTSHWPKDVSLAPNVKIMDWLPQTDLLAHPSIRLFVTHGGMNS 374

  Fly   375 VMEAVYSGVPILGLPVFFDQFINLRNVNLRGMAEVLDANEMTLEILTSTIRKLLENPRY--ALKA 437
            |||||:.|||::|:|.||||..|:..|..:.:...:....:..|....|::|::|:.||  |..|
Mouse   375 VMEAVHHGVPMVGIPFFFDQPENMVRVEAKNLGVSIQLQTLKAESFALTMKKIIEDKRYKSAAMA 439

  Fly   438 KKMSQSFRDRPMSPLDTAVWWTEYALRNKDASHMRLNTEDVPLYYEWDWG---------LLLGLR 493
            .|:.:  ...|::|....:.|.::.|:...|:|::      |..::..|.         .||||.
Mouse   440 SKIIR--HSHPLTPAQRLLGWIDHILQTGGAAHLK------PYAFQQPWHEQYMLDVFLFLLGLM 496

  Fly   494 FGIVFGSVIYLV 505
            .|.::.||..||
Mouse   497 LGTLWLSVKVLV 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B3	NP_651152.1	egt	7..466	CDD:223071	130/482 (27%)
Ugt3a2	NP_659094.1	UDPGT	23..488	CDD:278624	126/489 (26%)
Ugt3a2	NP_659094.1	egt	<235..488	CDD:223071	71/263 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840582
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.740