Protein Alignment Ugt303B3 and Ugt2b5

DIOPT Version :10

• Sequence 1: NP_651152.1
• Gene: Ugt303B3 / 42774
• FlyBaseID: FBgn0039085
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_033493.3
• Gene: Ugt2b5 / 22238
• MGIID: 98900
• Length: 530
• Species: Mus musculus
• Alignment Length: 577
• Identity: 145/577 - (25%)
• Similarity: 253/577 - (43%)
• Gaps: 131/577 - (22%)

  Fly     7 WLAVLFCLFLQKDLYQDSVQAANILGIFSYHFSSHNLVVRPLAKALVKRGHNVTLITPVG----- 66
            |::.|  |.||......||:...:| ::...| ||.:.::.:...||:|||.||::.|..
Mouse     5 WISAL--LLLQISCCFRSVKCGKVL-VWPMEF-SHWMNIKIILDELVQRGHEVTVLRPSAYYVLD 65

  Fly    67 -----------MPTDIE------------GVRHIRVPK-----LNQRVQEMIEGDQILDFFGSKW 103
                       .||.:.            .|....:|:     .:..:|.||  |:..|:|
Mouse    66 PKKSPGLKFETFPTSVSKDNLENFFIKFVDVWTYEMPRDTCLSYSPLLQNMI--DEFSDYF---- 124

  Fly   104 IASLMVVSMLYNMSSDILSDKGVQKMLQNRNERFDLVMLEPSA-----------LEALYGVVEHY 157
                      .::..|::|:|.:...||  ..:||:::.:|.|           :..||.:
Mouse   125 ----------LSLCKDVVSNKELMTKLQ--ESKFDVLLSDPVASCGELIAELLQIPFLYSI---- 173

  Fly   158 NATLMGFSGGNVNWSTEEVAGNF-APSINDPISSLGYSRSNSLLSKIYNWVHITEEKLLKHLIFR 221
                 .||.|   :..|:.:|.| .|....|:...|.....:.:.:|.|.:
Mouse   174 -----RFSPG---YQIEKSSGRFLLPPSYVPVILSGLGGQMTFIERIKNMI-------------- 216

  Fly   222 PSQLRIFKKFFN-FSEQKFYNMREKY-----SVILVNNHISMGRVRSN---------VPNIIEVG 271
              .:..|..:|. |:::|:.:...:|     :::.......|..:|||         :||:..||
Mouse   217 --CMLYFDFWFQMFNDKKWDSFYSEYLGRPTTLVETMGQAEMWLIRSNWDLEFPHPTLPNVDYVG 279

  Fly   272 GLHLTEPAEPCDSKLQKFMDDA-EHGVIYFSMGQEIMVQFLPEDMQQNLMKSLDQFKQRVVWKTE 335
            ||| .:||:|....:::|:..: :|||:.||:|.  ||..:.|:....:..:|.|..|:|:||.:
Mouse   280 GLH-CKPAKPLPKDMEEFVQSSGDHGVVVFSLGS--MVSNMTEEKANAIAWALAQIPQKVLWKFD 341

  Fly   336 LYNMPNKSDNVYVIEQPPQRAVLAHPNTRLFITNGGLLSVMEAVYSGVPILGLPVFFDQFINLRN 400
            .........|..|.:..||..:|.||.|:.|:|:||...|.||:|.|:|::|:|:|.:|..|:.:
Mouse   342 GKTPATLGHNTRVYKWLPQNDLLGHPKTKAFVTHGGANGVYEAIYHGIPMIGIPLFGEQHDNIAH 406

  Fly   401 VNLRGMAEVLDANEMTLEILTSTIRKLLENPRYALKAKKMSQSFRDRPMSPLDTAVWWTEYALRN 465
            :..:|.|..|:...|:...:.:.:.:::|||.|...|..:|....|:||.|||.||:|.|:.:|:
Mouse   407 MVAKGAAVALNIRTMSKSDVLNALEEVIENPFYKKNAMWLSTIHHDQPMKPLDRAVFWIEFVMRH 471

  Fly   466 KDASHMRLNTEDVPLYYEWDW---------GLLLGLRFGIVFGSV--IYLVYKLFQK 511
            |.|.|:|      ||.:...|         |.||......:..||  :..:|:.|.|
Mouse   472 KRAKHLR------PLGHNLTWYQYHSLDVIGFLLSCVATTIVLSVKCLLFIYRFFVK 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B3	NP_651152.1	GT1_Gtf-like	28..458	CDD:340817	120/490 (24%)
Ugt2b5	NP_033493.3	UDPGT	24..527	CDD:278624	138/556 (25%)