DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt303B3 and ugt-3

DIOPT Version :9

Sequence 1:	NP_651152.1	Gene:	Ugt303B3 / 42774	FlyBaseID:	FBgn0039085	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_506203.2	Gene:	ugt-3 / 191174	WormBaseID:	WBGene00013903	Length:	529	Species:	Caenorhabditis elegans

Alignment Length:	479	Identity:	111/479 - (23%)
Similarity:	200/479 - (41%)	Gaps:	58/479 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 ILGIFSYHFSSHNLVVRP------------LAKALVKRGHNVTLITPVGMPTDIEGVRHIRVPK- 81
            :|..|...|..:.|::.|            :|..|...||||||..|:    ..:...|.::.|
Worm     6 LLAFFPVAFGFNYLIISPVFGYSHMKFMGRIADILADAGHNVTLFQPI----IYDYYAHKKIVKN 66

  Fly    82 -----LNQRVQE----MIEGDQILDFF----GSK-WIASLMVVS-MLY----NMSSDILSDKGVQ 127
                 :|..|.|    ......:..||    ||| .|:|..:.| .||    ::...:|.||.:.
Worm    67 PNIEVINYEVDEEEKAAASEASVFKFFWKAKGSKNPISSAKITSEKLYKEFEHICRKMLLDKELH 131

  Fly   128 KMLQNRN------ERFDLVMLEPSALEALYGVVEHYNATLMGFSGGNVNWSTEEVAGNFAPSIND 186
            :.:.::|      |.||...|.......|...:..|:....|.:...|.   |.:..|:.|:
Worm   132 RWILSKNFDSHISEAFDFCGLYLGDFLKLKSPIPLYSGVRCGAASYAVG---EPIPLNYLPT--- 190

  Fly   187 PISSLGYSRSNSLLSKIYNWVHITEEKLLKHLIFRPSQLRIFKKFFNFSEQKFYNMREKYSVILV 251
              ....|.:.:|.:.::.:.:.:|.......::|.....:.: :....:.:.:..:.:..:..|.
Worm   191 --EGSNYGKKSSAIDRLSDMLGLTGYHFQFGILFDKQYDQAY-RLTGGNVRTWQEILQSSTFFLT 252

  Fly   252 NNHISMGRVRSNVPNIIEVGGLHLTE-PAEPCDSKLQKFMDDAEHGVIYFSMGQEIMVQFLPEDM 315
            |::..:......:..:|::||..:.. .....|.:..|.: ...:..|..|.|..|....:|:|.
Worm   253 NSNPYLSFSTPTISKVIQIGGFTIESFKTTTLDEEFNKIL-SLRNNTILVSFGTVIQSSDMPDDF 316

  Fly   316 QQNLMKSLDQFKQRV-VWKTEL--YNMPNK-SDNVYVIEQPPQRAVLAHPNTRLFITNGGLLSVM 376
            :..|:::..:..... :||.|.  ..:.|| |:||.:.:..||.|:||.....||:|:|||.|.|
Worm   317 KTGLIEAFRRMPDATFIWKYEEDDKTLKNKLSENVVLSKWIPQPALLADSRLDLFVTHGGLGSTM 381

  Fly   377 EAVYSGVPILGLPVFFDQFINLRNVNLRGMAEVLDANEMT-LEILTSTIRKLLENPRYALKAKKM 440
            |..|:||..:.:|||.||.:|...:...|.|.|.|..::. .:.|..||:.:|.|..|...:|::
Worm   382 EVGYAGVSSIMVPVFSDQGVNAEMLARHGGAIVYDKFDLVDSKKLMETIQMILNNSDYRKNSKRL 446

  Fly   441 SQSFRDRPMSPLDTAVWWTEYALR 464
            |....::||.|....:...|:|.|
Worm   447 SDILHNQPMDPKQVLLNHCEFAAR 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B3	NP_651152.1	egt	7..466	CDD:223071	111/479 (23%)
ugt-3	NP_506203.2	egt	1..457	CDD:223071	107/464 (23%)
ugt-3	NP_506203.2	UDPGT	27..525	CDD:278624	106/458 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.900