DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt303B3 and ugt-47

DIOPT Version :9

Sequence 1:	NP_651152.1	Gene:	Ugt303B3 / 42774	FlyBaseID:	FBgn0039085	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_505595.2	Gene:	ugt-47 / 187570	WormBaseID:	WBGene00011006	Length:	536	Species:	Caenorhabditis elegans

Alignment Length:	560	Identity:	126/560 - (22%)
Similarity:	217/560 - (38%)	Gaps:	122/560 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 SVQAANILGIFSYHFSSHNLVVRP------------LAKALVKRGHNVTLITPVGMPTDIEGV-- 74
            |:....||..|.|..:...||..|            :|..|.|.||||||     :..|..|:
Worm     6 SILLLAILYFFEYGLAYKILVFSPATSKSHLISNGRIADELAKAGHNVTL-----LEIDFLGIVD 65

  Fly    75 ----------RHIRVPKLNQRVQEMIEGDQILDFFGSKWIASLMVVSMLYNMSSDILSDKGV--- 126
                      ..:||||..|..:.:|:                       :.|..::.|:|:
Worm    66 STKSAKLVKKTIVRVPKKMQGFKNVIQ-----------------------SFSEGVMEDEGLFEL 107

  Fly   127 ---------------QKMLQN-------RNERFDLVMLEPSAL------EALYGVVEHYNATLMG 163
                           ::.|:|       ::|.||....|...:      :|| |:...:..:...
Worm   108 LKGNIAYQTVYNDLCEEFLENEVMFNKLKDENFDAFFAEQLNICGFGYAKAL-GIQRKFLISSCP 171

  Fly   164 FSGGNVNWSTEEVAGNFAPSINDPISSLGY-SRSNSLLS--KIYNWVHITEEKLLKHLIFRPSQL 225
            |.....::::........|.|:|......| .|:|:||.  .|..:.:.:..:|..
Worm   172 FFSHVYDYTSHPAPYASVPFISDMSPEPTYLERTNNLLRGITINTFFYFSHNRLTS--------- 227

  Fly   226 RIFKKFFNFSEQKFYNMREKYSVILVNNHISMGRVRSNVPNIIEVGGLHLTEPAEPCDSKLQKFM 290
             ||:|.|.........:.....:|.:.....:......:||::.||||.:.:.........:..|
Worm   228 -IFRKKFGDDFPAITEIVRNVDIIFLATDEIIDFSSPTLPNLVHVGGLGVDDDTTEMGPVFEAEM 291

  Fly   291 DDAEHGVIYFSMG---------QEIMVQFLPEDMQQNLMKSLDQFKQRVVWKTELYNMPNKS--- 343
            ...:.||||||:|         :::|..||      .::|....:...:.......|..:|:
Worm   292 KKGDKGVIYFSLGTIANTSTIDKKVMESFL------EIVKKFPDYHFLIRADKNDKNTKDKATEI 350

  Fly   344 DNVYVIEQPPQRAVLAHPNTRLFITNGGLLSVMEAVYSGVPILGLPVFFDQFINLRNVNLRGMAE 408
            .||:|.:..||.|:|.||..|.|||:.|...:|||..:|||::.:|..|||.:|.|.:..:|...
Worm   351 SNVFVSDWLPQPAILHHPRLRTFITHAGYNGLMEAALAGVPLITIPFMFDQNLNSRAIEKKGWGI 415

  Fly   409 VLDANEMTLE--ILTSTIRKLLENPRYALKAKKMSQSFRDRPMSPLDTAVWWTEYALRNKDASHM 471
            ..|..:...|  .:...||::|.||.|..:|.::....|::||...|..:..||:.::|.....:
Worm   416 RRDKKQFLTEPNAIEEAIREMLTNPSYTKQAHRVRDLMRNKPMGARDRFIKTTEWVIQNGGVHEL 480

  Fly   472 RLNTEDVPL--YYEWDWGLLLGLRFGIVFGSVIYLVYKLF 509
            .....|:.:  ||..|   ::...|.:.|..:|:..:|||
Worm   481 LTEGRDLSIIKYYNLD---IIVPCFFVAFYFIIFPFFKLF 517

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B3	NP_651152.1	egt	7..466	CDD:223071	115/513 (22%)
ugt-47	NP_505595.2	UDPGT	23..527	CDD:278624	121/543 (22%)
ugt-47	NP_505595.2	egt	<230..509	CDD:223071	72/287 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14096
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810