DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt303B3 and ugt-48

DIOPT Version :9

Sequence 1:	NP_651152.1	Gene:	Ugt303B3 / 42774	FlyBaseID:	FBgn0039085	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_504464.2	Gene:	ugt-48 / 178940	WormBaseID:	WBGene00015965	Length:	526	Species:	Caenorhabditis elegans

Alignment Length:	508	Identity:	131/508 - (25%)
Similarity:	211/508 - (41%)	Gaps:	106/508 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 SHNLVVRPLAKALVKRGHNVTLITPVGMP-TD----IEGVRHIRVPKLN----QRVQEMIEGDQI 95
            ||.:....:|..|...||.|....|..:. ||    .:..|...|..||    :::|..:.||..
Worm    30 SHMISQGRIADELANAGHEVVNFEPDFLNLTDKFVPCKKCRRWPVTGLNNYKFKKIQNGLSGDVF 94

  Fly    96 LDFFGSKWIASLMVVSMLYNMSSDILSDKGV---QKMLQN-------RNERFDL-----VMLEPS 145
            ..  .|.|       |.::|..||...|:..   ::|:.|       :.|:||.     :.|...
Worm    95 QQ--SSIW-------SKIFNTDSDPYQDEYTNMCEEMVTNKELIEKLKKEKFDAYFGEQIHLCGM 150

  Fly   146 ALEALYGVVEHYNATLMGFSGGNVNWSTEEVAG-NFAPSINDPISSLGYSRSNSLL--------- 200
            .|..|.|:...:             |    :|. ..:.|:.|   |||....:||:
Worm   151 GLAHLIGIKHRF-------------W----IASCTMSVSMRD---SLGIPTPSSLIPFMSTLDAT 195

  Fly   201 -----SKIYNWV----HITEEKLLKHLIFRPSQLR--IFKKFF--NFSEQKFYNMREKYSVILVN 252
                 .:..|:|    ||.:|       :|...|.  :|||.|  :|...:|  :.:...:|.|:
Worm   196 PAPFWQRAKNFVLQMAHIRDE-------YRDVVLTNDMFKKNFGSDFPCVEF--LAKTSDLIFVS 251

  Fly   253 NHISMGRVRSNVPNIIEVGGLHLTEPAEPCDSKLQKFMDDAEHGVIYFSMGQEIMVQFLPEDMQQ 317
            ....:......:.|::.:|||.|:......|.|..|.|:..: |||.||:|.......||..:.:
Worm   252 TDELLEIQAPTLSNVVHIGGLGLSSEGGGLDEKFVKIMEKGK-GVILFSLGTIANTTNLPPTIME 315

  Fly   318 NLMKSLDQFKQ-RVVWKTE-----LYNMPNKSDNVYVIEQPPQRAVLAHPNTRLFITNGGLLSVM 376
            ||||...:||. ..:.|.:     .:::.....||.|::..||.||||||..:.|||:.|..|:|
Worm   316 NLMKITQKFKDYEFIIKVDKFDRRSFDLAEGLSNVLVVDWVPQTAVLAHPRLKAFITHAGYNSLM 380

  Fly   377 EAVYSGVPILGLPVFFDQFINLRNVNLRGMAEVLDANEMTL--EILTSTIRKLLENPRYALKAKK 439
            |:.|:|||::.:|..|||..|.|:|..:|...:.|..::..  :.:...|:::|.||.|..||.:
Worm   381 ESAYAGVPVILIPFMFDQPRNGRSVERKGWGILRDRFQLIKDPDAIEGAIKEILVNPTYQEKANR 445

  Fly   440 MSQSFRDRPMSPLDTAVWWTEYALRNK-------DASHMRLNTEDVPLYYEWD 485
            :.:..|.:|.|..:..|..|.:.|.|.       :..||     |...:|..|
Worm   446 LKKLMRSKPQSASERLVKMTNWVLENDGVEELQYEGKHM-----DFFTFYNLD 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B3	NP_651152.1	egt	7..466	CDD:223071	125/480 (26%)
ugt-48	NP_504464.2	UDPGT	19..510	CDD:278624	131/508 (26%)
ugt-48	NP_504464.2	egt	<224..471	CDD:223071	76/249 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.710