Protein Alignment Ugt303B3 and UGT3A2

DIOPT Version :9

• Sequence 1: NP_651152.1
• Gene: Ugt303B3 / 42774
• FlyBaseID: FBgn0039085
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: XP_011512290.1
• Gene: UGT3A2 / 167127
• HGNCID: 27266
• Length: 550
• Species: Homo sapiens
• Alignment Length: 550
• Identity: 130/550 - (23%)
• Similarity: 230/550 - (41%)
• Gaps: 119/550 - (21%)

  Fly    26 QAANILGIFSYHFSSHNLVVRPLAKALVKRGHNVTLIT-------PVGMPTDIEGVRHIRV---- 79
            :||.||.| |....||.|::..:::.|...|||||::.       |....:.....|:.|:
Human    21 EAAKILTI-STVGGSHYLLMDRVSQILQDHGHNVTMLNHKRGPFMPGLSDSPASASRYPRILYLQ 84

  Fly    80 ------------------------PKLNQRVQEMIEGDQILDFF-------GSKWIASLMVVSML 113
                                    |:.:||     |..:..|||       ..|:...|.|:..|
Human    85 KYCQFGLKDFKKEEKSYQVISWLAPEDHQR-----EFKKSFDFFLEETLGGRGKFENLLNVLEYL 144

  Fly   114 YNMSSDILSDKGVQKMLQNRNERFDLVMLEPSALEALYGVVEHYNATLMGFSGGNVNWSTEEVAG 178
            ....|..|:.|.:...|  :||.||:|::|          ...|...|:          .|::..
Human   145 ALQCSHFLNRKDIMDSL--KNENFDMVIVE----------TFDYCPFLI----------AEKLGK 187

  Fly   179 NFAPSINDPISSLGYSRSNSLLSKIYNWVHITEEKLLKHLIFRPSQLRIFKKFFNFSEQK----- 238
            .|...::....||.:.....|     ::|.:....|..|:.|. .:::.|..||:|..::
Human   188 PFVAILSTSFGSLEFGLPIPL-----SYVPVFRSLLTDHMDFW-GRVKNFLMFFSFCRRQQHMQS 246

  Fly   239 -FYN-MRE---------------KYSVILVNNHISMGRVRSNVPNIIEVGGLHLTEPAEPCDSKL 286
             |.| ::|               |..:..:|:..:....|..:||.:.|||| :.:|.:|....|
Human   247 TFDNTIKEHFTEGSRPVLSHLLLKAELWFINSDFAFDFARPLLPNTVYVGGL-MEKPIKPVPQDL 310

  Fly   287 QKFMDD-AEHGVIYFSMGQEIMVQFLPEDMQQNLMKSLDQFKQRVVWKTELYNMP---NKSDNVY 347
            :.|:.. .:.|.:..::|..:.....||..:: :..:.....|.|:||.:..:.|   :.:.||.
Human   311 ENFIAKFGDSGFVLVTLGSMVNTCQNPEIFKE-MNNAFAHLPQGVIWKCQCSHWPKDVHLAANVK 374

  Fly   348 VIEQPPQRAVLAHPNTRLFITNGGLLSVMEAVYSGVPILGLPVFFDQFINLRNVNLRGMAEVLDA 412
            :::..||..:||||:.|||:|:||..|:|||:..|||::|:|:|.||..|:..|..:.....:..
Human   375 IVDWLPQSDLLAHPSIRLFVTHGGQNSIMEAIQHGVPMVGIPLFGDQPENMVRVEAKKFGVSIQL 439

  Fly   413 NEMTLEILTSTIRKLLENPRYALKAKKMSQSFRDRPMSPLDTAVWWTEYALRNKDASHMRLNTED 477
            .::..|.|...:::::|:.||...|...|...|..|:||....|.|.::.|:...|:|::
Human   440 KKLKAETLALKMKQIMEDKRYKSAAVAASVILRSHPLSPTQRLVGWIDHVLQTGGATHLK----- 499

  Fly   478 VPLYYEWDWG---------LLLGLRFGIVF 498
             |..::..|.         .||||..|.::
Human   500 -PYVFQQPWHEQYLLDVFVFLLGLTLGTLW 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B3	NP_651152.1	egt	7..466	CDD:223071	121/507 (24%)
UGT3A2	XP_011512290.1	UDPGT	23..518	CDD:278624	124/536 (23%)
		egt	<162..517	CDD:223071	92/388 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150554
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.740