Protein Alignment Ugt303B3 and UGT3A1

DIOPT Version :9

• Sequence 1: NP_651152.1
• Gene: Ugt303B3 / 42774
• FlyBaseID: FBgn0039085
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_689617.3
• Gene: UGT3A1 / 133688
• HGNCID: 26625
• Length: 523
• Species: Homo sapiens
• Alignment Length: 546
• Identity: 129/546 - (23%)
• Similarity: 238/546 - (43%)
• Gaps: 122/546 - (22%)

  Fly    26 QAANILGIFSYHFSSHNLVVRPLAKALVKRGHNVTLITPVG---MPTDIEGVRHIRV-----PKL 82
            :||.||.| |....||.|::..:::.|.:.|||||::...|   :|...|..:..:|     |:.
Human    21 EAAKILTI-STLGGSHYLLLDRVSQILQEHGHNVTMLHQSGKFLIPDIKEEEKSYQVIRWFSPED 84

  Fly    83 NQR---------VQEMIEGD-------QILDFFGSKWIASLMVVSMLYNMSSDILSDKGVQKMLQ 131
            :|:         ::..::|.       ::::.||::              .|.:||.|.:...|
Human    85 HQKRIKKHFDSYIETALDGRKESEALVKLMEIFGTQ--------------CSYLLSRKDIMDSL- 134

  Fly   132 NRNERFDLVMLEPSALEALYGVVEHYNATLMGFSGGNVNWSTEEVAGNFAPSINDPISSLGYSRS 196
             :||.:|||.:|  |.:....::                  .|::...|...:.....||.:...
Human   135 -KNENYDLVFVE--AFDFCSFLI------------------AEKLVKPFVAILPTTFGSLDFGLP 178

  Fly   197 NSLLSKIYNWVHITEEKLLKHLIFRPSQLRIFKKFFNFSEQKFYNMRE----------------- 244
            :.|     ::|.:....|..|:.|. .:::.|..||:||..: ::|:.
Human   179 SPL-----SYVPVFPSLLTDHMDFW-GRVKNFLMFFSFSRSQ-WDMQSTFDNTIKEHFPEGSRPV 236

  Fly   245 ------KYSVILVNNHISMGRVRSNVPNIIEVGGLHLTEPAEPCDSKLQKFMDD-AEHGVIYFSM 302
                  |..:..||:..:....|..:||.:.:||| :.:|.:|....|..|:.: .:.|.:..:.
Human   237 LSHLLLKAELWFVNSDFAFDFARPLLPNTVYIGGL-MEKPIKPVPQDLDNFIANFGDAGFVLVAF 300

  Fly   303 GQEIMVQFLPEDMQQNLMKSLD----QFKQRVVWKTELYNMP---NKSDNVYVIEQPPQRAVLAH 360
            |     ..|.....|.::|.:.    ...|.|:|..:..:.|   :.:.||.:::..||..:|||
Human   301 G-----SMLNTHQSQEVLKKMHNAFAHLPQGVIWTCQSSHWPRDVHLATNVKIVDWLPQSDLLAH 360

  Fly   361 PNTRLFITNGGLLSVMEAVYSGVPILGLPVFFDQFINLRNVNLRGMAEVLDANEMTLEILTSTIR 425
            |:.|||:|:||..|||||:..|||::||||..||..|:..|..:.....:..|::|.:.||.|::
Human   361 PSIRLFVTHGGQNSVMEAIRHGVPMVGLPVNGDQHGNMVRVVAKNYGVSIRLNQVTADTLTLTMK 425

  Fly   426 KLLENPRYALKAKKMSQSFRDRPMSPLDTAVWWTEYALRNKDASHMRLNTEDVPLYYEWDWG--- 487
            :::|:.||.......|.....:|:||....|.|.::.|:...|:|::      |..::..|.
Human   426 QVIEDKRYKSAVVAASVILHSQPLSPAQRLVGWIDHILQTGGATHLK------PYAFQQPWHEQY 484

  Fly   488 ------LLLGLRFGIVF--GSVIYLV 505
                  .||||..|.::  |.::.:|
Human   485 LIDVFVFLLGLTLGTMWLCGKLLGVV 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B3	NP_651152.1	egt	7..466	CDD:223071	118/494 (24%)
UGT3A1	NP_689617.3	UDPGT	23..523	CDD:330975	128/544 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150068
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.740