Protein Alignment Ugt303B3 and Ugt1a6

DIOPT Version :10

• Sequence 1: NP_651152.1
• Gene: Ugt303B3 / 42774
• FlyBaseID: FBgn0039085
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_476446.2
• Gene: Ugt1a6 / 113992
• RGDID: 620949
• Length: 530
• Species: Rattus norvegicus
• Alignment Length: 531
• Identity: 126/531 - (23%)
• Similarity: 229/531 - (43%)
• Gaps: 124/531 - (23%)

  Fly    40 SHNLVVRPLAKALVKRGHNVTLITP-----VG-----------MPTDIEGVRHIRVPKLNQRVQE 88
            ||.|.::.:.:.|.:|||::.::.|     :|           :|.::|        :|..|.:.
  Rat    36 SHWLSMKEIVEHLSERGHDIVVLVPEVNLLLGESKYYRRKSFPVPYNLE--------ELRTRYRS 92

  Fly    89 MIEGDQILDFFGSKWIA--------------SLMVVSMLYNMSSDILSDKGVQKMLQNRNERFDL 139
                      ||:...|              :::|:.|.:.....:|.|......|  |..:||.
  Rat    93 ----------FGNNHFAASSPLMAPLREYRNNMIVIDMCFFSCQSLLKDSATLSFL--RENQFDA 145

  Fly   140 VMLEPS-----------ALEALYGVVEHYNATLMGFSGGNVNWSTEEVAGNFAPSINDPISSLGY 193
            :..:|:           .|.::|        ...||.     .|.|.:.|. :||   |:
  Rat   146 LFTDPAMPCGVILAEYLKLPSVY--------LFRGFP-----CSLEHMLGQ-SPS---PV----- 188

  Fly   194 SRSNSLLSKIYNWVHITEEKLLKHLIFRPSQLRIFKKFFNFSEQKFYN-MREKYSVI---LVNNH 254
                |.:.:.|.       |...|:.| |.:|..|  ..|..|...|: :..||.::   |:...
  Rat   189 ----SYVPRFYT-------KFSDHMTF-PQRLANF--IANILENYLYHCLYSKYEILASDLLKRD 239

  Fly   255 ISMGRVRSN-----------------VPNIIEVGGLHLTEPAEPCDSKLQKFMD-DAEHGVIYFS 301
            :|:..:..|                 :||:|.:||.:..:... ...:.:.::: ..|||::.||
  Rat   240 VSLPALHQNSLWLLRYDFVFEYPRPVMPNMIFIGGTNCKKKGN-LSQEFEAYVNASGEHGIVVFS 303

  Fly   302 MGQEIMVQFLPEDMQQNLMKSLDQFKQRVVWKTELYNMPNKSDNVYVIEQPPQRAVLAHPNTRLF 366
            :|.  ||..:||.....:.::|.:..|.|:|:.......|.:.|..:::..||..:|.||..|.|
  Rat   304 LGS--MVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKARAF 366

  Fly   367 ITNGGLLSVMEAVYSGVPILGLPVFFDQFINLRNVNLRGMAEVLDANEMTLEILTSTIRKLLENP 431
            ||:.|...:.|.:.:|||::.:|:|.||..|.:.:..||....|:..|||.:.|.:.::.::.|.
  Rat   367 ITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNK 431

  Fly   432 RYALKAKKMSQSFRDRPMSPLDTAVWWTEYALRNKDASHMRLNTEDVPLYYEWDWGLLLGLRFGI 496
            .|.....::|...:|||:.|||.||:|.||.:|:|.|.|:|....|: .:|::....::|....|
  Rat   432 SYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDL-TWYQYHSLDVIGFLLAI 495

  Fly   497 VFGSVIYLVYK 507
            |. :|:::|||
  Rat   496 VL-TVVFIVYK 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B3	NP_651152.1	GT1_Gtf-like	28..458	CDD:340817	109/480 (23%)
Ugt1a6	NP_476446.2	UDPGT	26..521	CDD:278624	126/531 (24%)