DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt303B3 and ugt5a4

DIOPT Version :9

Sequence 1:	NP_651152.1	Gene:	Ugt303B3 / 42774	FlyBaseID:	FBgn0039085	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_001170969.2	Gene:	ugt5a4 / 100415798	ZFINID:	ZDB-GENE-100406-1	Length:	525	Species:	Danio rerio

Alignment Length:	531	Identity:	132/531 - (24%)
Similarity:	233/531 - (43%)	Gaps:	94/531 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 SHNLVVRPLAKALVKRGHNVTLI-----------TPVGMPTDIEGVRHIRVPKLNQRVQEMIEGD 93
            ||.:.::.|...|..:||::|::           :|:.....:|                  .|:
Zfish    33 SHWINMKVLLVELHSKGHSITVVRASNSWYIEEQSPLYTSITVE------------------NGE 79

  Fly    94 QILDFFGSKWIASLMVV-----SMLYNMSSDILSDKGVQKMLQNRNE--RFDLVMLEPSAL---- 147
            ...| ||.|::..|:.:     |....|:   |:|:...:..:...|  :....|.|...|
Zfish    80 FDAD-FGEKFLPHLLKMQRQGKSFWTEMA---LADETYSRFTEIHQEICKMTATMFENETLMNSL 140

  Fly   148 -EALYGVVEHYNATLMGFSGG-------------NVNWST-EEVAGNFAPSIND--PISSLGYSR 195
             :|.|.||    .|...|.||             ||.|:. .|.....|||...  |:|.|..:.
Zfish   141 KDAAYDVV----LTDPAFGGGVLLAHRLGLPLVFNVRWTMYGEAHFVIAPSPLSYVPVSGLQLTD 201

  Fly   196 SNSLLSKIYNWVHITEEKLLKHLIFRPSQLRIFKKFFNFSEQKFYNMREKYSVILVNNHISMGRV 260
            ..:...::.|.:............|......:.:|:|. ....|:::.:...:.|:.|..:....
Zfish   202 KMTFSQRVMNMMTYIMILYKNSKYFGSPYQELTQKYFG-PNVNFFSLLQDADLWLMRNDFTFEFP 265

  Fly   261 RSNVPNIIEVGGLHLTEPAEPCDSKLQKFMDDA-EHGVIYFSMGQEIMVQFLPEDMQQNLMKSLD 324
            |..:||::.:||.. .:||:|....|::|:..: |||||..|:| .:..|.|.| :...:..:..
Zfish   266 RPTMPNVVYMGGFQ-CKPAKPLPGDLEEFVQSSGEHGVIMMSLG-AVFGQLLSE-LNDEIAAAFA 327

  Fly   325 QFKQRVVWKTELYNMP---NKSDNVYVIEQPPQRAVLAHPNTRLFITNGGLLSVMEAVYSGVPIL 386
            |..|:|:|:   |..|   |..:|..::...||..:|.||.|:||:.:||...:.||:|.||||:
Zfish   328 QLPQKVIWR---YTGPRPANLGNNSLIVNWLPQNDLLGHPKTKLFVAHGGTNGLQEAIYHGVPIV 389

  Fly   387 GLPVFFDQFINLRNVNLRGMAEVLDANEMTLEILTSTIRKLLENPRYALKAKKMSQSFRDRPMSP 451
            |||:.|||..||..:..:|.|:::|...:...:....::::|.||.|....:::|:...|:||.|
Zfish   390 GLPLAFDQPDNLSRMRAKGTAKIVDIATLDRAVFLEALKEVLHNPSYRENMQRLSKLHHDQPMKP 454

  Fly   452 LDTAVWWTEYALRNKDASHMRLNTEDVPLYYEWDW------GLLLGLRFGIVFGSVI------YL 504
            ||.|::|.|:.:|||.|.|:|..:      :...|      .::|.|...::..:::      |.
Zfish   455 LDRAIFWIEFVMRNKGAPHLRTQS------FRMSWIEYQSIDVILTLMVMVLVFALVTAYMTKYF 513

  Fly   505 VYKLFQKTSAR 515
            ..:||:|...|
Zfish   514 CLRLFRKKVKR 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B3	NP_651152.1	egt	7..466	CDD:223071	119/468 (25%)
ugt5a4	NP_001170969.2	UDPGT	23..525	CDD:278624	132/531 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000