DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt303B3 and ugt5b3

DIOPT Version :9

Sequence 1:	NP_651152.1	Gene:	Ugt303B3 / 42774	FlyBaseID:	FBgn0039085	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_001348442.1	Gene:	ugt5b3 / 100415792	ZFINID:	ZDB-GENE-100406-5	Length:	534	Species:	Danio rerio

Alignment Length:	536	Identity:	138/536 - (25%)
Similarity:	261/536 - (48%)	Gaps:	72/536 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 VQAANILGIFSYHFSSHNLVVRPLAKALVKRGHNVTLI---------------TPV------GMP 68
            |::.|:| :|.... ||.:.:..|.:||..:|||:|::               |.|      |:.
Zfish    24 VESGNVL-VFPVDV-SHWVNMNVLVEALHAKGHNITVMRMADSWYIKEFSPHYTSVNLKSSGGLS 86

  Fly    69 TDIEGVRHIRVPKLNQRVQEMIEGDQILDFFG------SKWIASLMVVSMLYNMSSDILSDKGVQ 127
            .|..|      |.:::.:..:.||..    :|      ..|..||.::.:...|.::::.|   |
Zfish    87 EDFIG------PFVSRLMNILREGST----WGRLKLEIEMWQTSLKMIEIEREMITNMIED---Q 138

  Fly   128 KMLQN-RNERFDLVMLEPSALEALYG--VVEHYNATLMGFSGGNVNWSTEEVAGNFA----PSIN 185
            :::|: :..:|||::.:|    |:||  ::.||....:.:   ||.| |....|:||    |...
Zfish   139 QLMQSLKKAKFDLILTDP----AMYGGVMLGHYLKLPIVY---NVRW-TIFGEGHFAIAPSPLSY 195

  Fly   186 DPISSLGYSRSNSLLSKIYNWVH--ITEEKLLKHLIFRPSQLRIFKKFFNFSEQKFYNMREKYSV 248
            .|:..|......|.|.::.|.|.  |||.::.  .:..|:...:.::|.. .|..|.|:.::..:
Zfish   196 VPVPMLEIPDRMSFLERVKNVVMYIITETQIA--FLIAPTYNALCERFIG-PEVNFGNLVQEADL 257

  Fly   249 ILVNNHISMGRVRSNVPNIIEVGGLHLTEPAEPCDSKLQKFMDDA-EHGVIYFSMGQEIMVQFLP 312
            .|..........|..:|||:.:.|.. .:|::|....|:.|:..: :||||..|:|  .::..||
Zfish   258 WLHRADFVFEYPRPTMPNIVYMAGFQ-CKPSKPLPQDLEDFVQSSGDHGVIVMSLG--TLIGQLP 319

  Fly   313 EDMQQNLMKSLDQFKQRVVWKTELYNMPNKSDNVYVIEQPPQRAVLAHPNTRLFITNGGLLSVME 377
            :|:.:.:.::..:..|:::|:.:........:|..|::..||..:|.||.||.|:.:||...|.|
Zfish   320 DDVAEAIAEAFAELPQKIIWRYKGKRPSALGNNTLVMDWMPQNDLLGHPKTRAFVAHGGTNGVQE 384

  Fly   378 AVYSGVPILGLPVFFDQFINLRNVNLRGMAEVLDANEMTLEILTSTIRKLLENPRYALKAKKMSQ 442
            |:|.||||:|..:.|||..||..:.:||.|:.:|...|..|....|::::|.:|.|....:::|:
Zfish   385 AIYHGVPIIGFGLIFDQPDNLSKMRVRGAAKNVDFATMDKESFLKTVKEVLYDPSYRENMQRLSR 449

  Fly   443 SFRDRPMSPLDTAVWWTEYALRNKDASHMRLNTEDVPLYYEWDWGLLLGLRFGI------VFGSV 501
            ..:|.|:.|||.|::|.|:.:|:|.|:|:|..:..:|.|......::|.|...:      ::..:
Zfish   450 LHKDVPVKPLDNAIFWIEFVMRHKGAAHLRTESYKMPWYSYHSVDVILVLISAVSLIILSIYAVI 514

  Fly   502 IYLVYKLFQKTSARRR 517
            .|...::..:|:..:|
Zfish   515 RYFCCRICMRTTKNKR 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B3	NP_651152.1	egt	7..466	CDD:223071	127/477 (27%)
ugt5b3	NP_001348442.1	UDPGT	27..531	CDD:278624	137/533 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584519
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	252	1.000	Inparanoid score	I3189
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.790