Protein Alignment Ugt303B3 and ugt2a1

DIOPT Version :10

• Sequence 1: NP_651152.1
• Gene: Ugt303B3 / 42774
• FlyBaseID: FBgn0039085
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_001177979.1
• Gene: ugt2a1 / 100006320
• ZFINID: ZDB-GENE-080721-20
• Length: 539
• Species: Danio rerio
• Alignment Length: 559
• Identity: 152/559 - (27%)
• Similarity: 257/559 - (45%)
• Gaps: 88/559 - (15%)

  Fly    10 VLFCLFLQKDLYQDSVQAANILGIFSYHFSSHNLVVRPLAKALVKRGHNVTLITPVGMP----TD 70
            :|..|.|.::|.  .|....|| ::...| ||.|.::.:...|::||||:|::|....|    |.
Zfish    11 LLLALLLNQNLL--CVSGGKIL-VWPAEF-SHWLNIKVILDVLIERGHNITVVTHTATPSVQTTP 71

  Fly    71 IEG--VRHIRVPKLNQRVQEMIE-----------GDQILDFFGSKWIASLMVVSMLYNMS----- 117
            ..|  ...::||...|.:.:.:|           .|.|:       .|||.:..|:...:
Zfish    72 SAGYNAEILQVPYTKQEIVDNLERMLKYWTHDLPNDNII-------TASLKIHEMITTATAQNKI 129

  Fly   118 --------SDILSDKGVQKMLQNRNERFDLVMLEPSALEALYGVVEHYNATL-------MGFSGG 167
                    :|:|..   .||     |:||:::.:|     ||...|.....|       :.|:.|
Zfish   130 TCNALFSRADLLEK---WKM-----EKFDVILADP-----LYICGEILAQKLDIPLIFSLRFTFG 181

  Fly   168 NVNWSTEEVAGNF-APSINDPISSLGYSRSNSLLSKIYNWVHITEEKLLKHLIFRPSQLRIFKKF 231
            |   :.|.:.|.. ||....|..:...:.....:.::.|::....:..|.:|:.:      ||..
Zfish   182 N---TLERLCGQMPAPPSYVPAVASEKTDQMDFIDRLKNFLFYGMQDFLFYLVTK------FKWD 237

  Fly   232 FNFSE--QKFYNMRE---KYSVILVNNHISMGRVRSNVPNIIEVGGLHLTEPAEPCDSKLQKFMD 291
            ..:||  .|...|.|   |..:.|:..:......|...||...||||| .:||:|...::::|:.
Zfish   238 HYYSEVLGKPTTMCETMGKADIWLIRTYWDFEYPRPFPPNFKFVGGLH-CKPAKPLSKEMEEFVQ 301

  Fly   292 DA-EHGVIYFSMGQEIMVQFLPEDMQQNLMKSLDQFKQRVVWKTELYNMPNKSDNVYVIEQPPQR 355
            .: :|||:.||:|.  |::.|..:....:..:|.|..|:|||:.........:.|..:.:..||.
Zfish   302 SSGDHGVVVFSLGS--MIKNLTSERANTIAAALGQIPQKVVWRYSGKTPETLAPNTKIYDWIPQN 364

  Fly   356 AVLAHPNTRLFITNGGLLSVMEAVYSGVPILGLPVFFDQFINLRNVNLRGMAEVLDANEMTLEIL 420
            .:|.||.|:.|||:||...:.||:|.|||::|||:|.||..||.::..:|.|.|||.|.:..:.|
Zfish   365 DLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFADQPDNLLHMKTKGAAVVLDINTLESKDL 429

  Fly   421 TSTIRKLLENPRYALKAKKMSQSFRDRPMSPLDTAVWWTEYALRNKDASHMRLNTEDVPLYYEWD 485
            ...::.:|.||.|.....::|:...|:||.|||.||:|.|:.:|||.|.|:|:...::. :|::.
Zfish   430 VDALKTVLNNPSYKESIMRLSRIHHDQPMKPLDQAVYWIEFVMRNKGAKHLRVQAHELS-WYQYH 493

  Fly   486 W----GLLLGLRFGIVF---GSVIYLVYKLFQKTSARRR 517
            .    ..||.:...|.|   .:..:|..:..:||...|:
Zfish   494 CLDVAAFLLSIAALITFLWVKACCFLFRRCVRKTRPERK 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B3	NP_651152.1	GT1_Gtf-like	28..458	CDD:340817	130/473 (27%)
ugt2a1	NP_001177979.1	UDPGT	27..526	CDD:278624	144/533 (27%)