Protein Alignment CG10175 and Ces3a

DIOPT Version :10

• Sequence 1: NP_001287487.1
• Gene: CG10175 / 42773
• FlyBaseID: FBgn0039084
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: XP_038954062.1
• Gene: Ces3a / 689754
• RGDID: 1588734
• Length: 563
• Species: Rattus norvegicus
• Alignment Length: 593
• Identity: 142/593 - (23%)
• Similarity: 223/593 - (37%)
• Gaps: 144/593 - (24%)

  Fly   158 TSLGKVRGRYQKYRSGERGGYYSFKGMRYGAPPTGARRFRAAEPEKPWSGIRDASREGQSC---- 218
            |..|.|:|:....::.|. ....|..:.:...|.|..:|....|.:||.|:|.||.....|
  Rat    41 TPXGHVQGQQVGVKNTEH-VVNVFLSIPFAQAPLGXLQFSVPLPXQPWEGVRVASTNLPMCLQDV 104

  Fly   219 ---------PHKNMILDTFKGDEDCLFVNVFTTQMPKDDESAEQPKLPVMVWLHGGGFSFGSGNS 274
                     |::..::  |...||||.::         .|.....|..||||:||.....||..:
  Rat   105 ERMNSSRFTPNEKHLI--FPISEDCLILS---------XEITAGTKRLVMVWIHGESLEVGSATA 158

  Fly   275 ------FLYGPDYLVAEDIVLVTLNYRLGPLGFLTAG-PDAPGNQGLKDQVLALKWVRDNIAAFG 332
                  ..||       .:|:||:.|.|...|||:.| ...|.|:|..|.|.||.|::.|||.||
  Rat   159 QDGSALAAYG-------GVVVVTVQYHLRIFGFLSTGDKHMPSNRGFLDVVAALCWIQGNIAPFG 216

  Fly   333 GDPNQVTIFGESAGASSVQLLLLSSQAKGLFHRAISQSGSALNPWSMSASSSQRAARLAANLGYV 397
            |:||.||:||.|||.|.|..|:||....||.|||||||| .:....|...::...||..||....
  Rat   217 GEPNCVTVFGNSAGGSIVSSLVLSPMFAGLSHRAISQSG-VITTRMMKEMNTXPXARNFANSVAC 280

  Fly   398 GANKTEDILDFLRRVPAMKLVEAAPTTITAEDQRNNIGLPFVPVVEGYWNQDSQEEQFYEEPFLT 462
            .:....:::..|.:.....|::            .|:.:.::           ..:.|.:.|
  Rat   281 SSGSPAELVQCLLQKEEKDLIQ------------KNVNVSYI-----------INDSFPQRP--- 319

  Fly   463 QHPSDMYHSQNFNSDVAYMTGYNTHEAMLFIRRLRKNPQLLSIIENDFGRLVPQDLNVTESHDRV 527
                                     |.:|..|:|...|.||.:..::||.|:.:..|:.:..:.:
  Rat   320 -------------------------EKILTDRQLPTVPYLLGVTNHEFGWLILRIWNILDKLEHL 359

  Fly   528 TRE----IRSFYLGSKHVGIESVDEMI------------------ALLTDLMFLQGIRRTARNHA 570
            :.|    |...:|....|..|.:..:|                  .||.|:..:..|    .|.:
  Rat   360 SPEDLLDISRPFLALMEVPPEIMPTVIDQYLDNGSDESATKYAFQELLGDITLIIPI----LNFS 420

  Fly   571 KF---GNAPVYMYRF-SFDGSLGLYKRMLGIPRPGVCHGDELGYLFKFGFF----NLSLDPKSM- 626
            |:   ...||.:|.| :...|...:|.......    |..|..::|...|.    :|...|::.
  Rat   421 KYLQDAGCPVLLYEFQNTPNSFAKFKSAWVKAE----HASENSFVFGGPFLIEESSLLAFPEATE 481

  Fly   627 -EVQVKNRMVRMWTNFAKYGSPTPDSEDPMLTTKWAPIDPTNVMNSL-NYMDISANLAMKTNPEP 689
             |.|:...|:..|:. :..|:|......|     |..      :|.| .|:::..........:.
  Rat   482 EEKQLSLTMIAQWSQ-SHTGNPNGKELPP-----WPQ------LNQLEQYLEVGLEPQTGVKLKK 534

  Fly   690 ERQRFWDE 697
            .|.:||.|
  Rat   535 GRLQFWTE 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10175	NP_001287487.1	COesterase	155..695	CDD:395084	139/589 (24%)
Ces3a	XP_038954062.1	COesterase	35..540	CDD:395084	139/589 (24%)