Protein Alignment CG10175 and nlgn2a

DIOPT Version :10

• Sequence 1: NP_001287487.1
• Gene: CG10175 / 42773
• FlyBaseID: FBgn0039084
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: XP_009301340.1
• Gene: nlgn2a / 556158
• ZFINID: ZDB-GENE-090918-2
• Length: 828
• Species: Danio rerio
• Alignment Length: 680
• Identity: 190/680 - (27%)
• Similarity: 289/680 - (42%)
• Gaps: 164/680 - (24%)

  Fly   107 AHMGSSTTETTA------WKTLTSHPNSLVQLLPSRAMRVVQEVVRSLRKEREIVATTSLGKVRG 165
            || .|..|.|.|      |.||.    |..::.|......|               ||:.||:||
Zfish    14 AH-NSEVTHTIALFWLALWITLA----SCQRIDPGTKYPTV---------------TTNYGKLRG 58

  Fly   166 RYQKYRSGERGGYYSFKGMRYGAPPTGARRFRAAEPEKPWSGIRDASREGQSCPHK------NMI 224
            ..::..:...|....:.|:.|...|.|.|||:..|....|..:|:|::....||..      .::
Zfish    59 IKKELNNEILGPVEQYLGVPYATAPIGDRRFQPPEAPGSWQEVRNATQFAPVCPQNVHGVLPEIM 123

  Fly   225 LDTFKGD-------------EDCLFVNVF---------------TTQMPKDDESAEQPKLPVMVW 261
            |..:..|             ||||::||:               |...|:|::..::.|.|||::
Zfish   124 LPVWFTDSLDVAATYIQNQSEDCLYLNVYVPTEDGPLTKKHDESTLNRPRDEDIRDRRKKPVMLF 188

  Fly   262 LHGGGFSFGSGNSF------LYGPDYLVAEDIVLVTLNYRLGPLGFLTAG-PDAPGNQGLKDQVL 319
            :|||.:..|:||.|      .||       ::::||:|||||.||||:.| ..|.||.||.||:.
Zfish   189 IHGGSYMEGTGNMFDASVLAAYG-------NVIVVTMNYRLGVLGFLSTGDQSAKGNYGLLDQIQ 246

  Fly   320 ALKWVRDNIAAFGGDPNQVTIFGESAGASSVQLLLLSSQAKGLFHRAISQSGSALNPWSMSASSS 384
            ||:|:.:||..|||||.::||||..||||.|.||:||..::|||.|||:|||||::.||:|....
Zfish   247 ALRWLNENIGHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFQRAIAQSGSAISSWSISYQPL 311

  Fly   385 QRAARLAANLGYVGANKTEDILDFLRRVPAMKLVEAAPTTITAEDQRNNIGLPFVPVVEGYWNQD 449
            :....||..:|.. ..:|.|::|.|||....:||:       .:.|.....:.|.||::|....|
Zfish   312 KYTKILARKVGCT-YGETADLVDCLRRKNFRELVD-------QDIQPARYHIAFGPVMDGDVVPD 368

  Fly   450 SQEEQFYEEPFLTQHPSDMYHSQNFNSDVAYMTGYNTHEAMLF-----------IRRLRKNPQLL 503
            ..|....:..||             |.|:  :.|.|..|.:.|           |.....:..:.
Zfish   369 DPEILMQQGEFL-------------NYDL--LIGVNQGEGLKFVDDGGTESEEGISAAAFDYTIS 418

  Fly   504 SIIENDFGRLVPQDL-------NVTESHDRVTREIRSFYLGSKHVGIESVDEMIALLTDLMFLQG 561
            :.::|.:|....:|:       ..|:..||...|:|.             ..::||.||..::..
Zfish   419 NFVDNLYGYPKGKDILRETIKFMYTDWADRDNGEMRR-------------KTLLALFTDHQWVAP 470

  Fly   562 IRRTARNHAKFGNAPVYMYRFSFDGSLGLYKRMLGIPRP---GVCHGDELGYLFKFGFFNLS-LD 622
            ...||:.||.: .:|||.|.|        |.......||   ...||||:.|:|.......: |.
Zfish   471 AIATAKLHADY-QSPVYFYTF--------YHHCQTETRPEWADAAHGDEIPYVFGVPMIGATDLF 526

  Fly   623 P---KSMEVQVKNRMVRMWTNFAKYGSPT-------------PDSEDPMLTTKWAPIDPTNVMNS 671
            |   ...::.:...::..||||||.|.|.             |:..:.::.||:...|.
Zfish   527 PCNFSKNDIMLSAVVMTYWTNFAKTGDPNLPVPQDTKFIHTKPNRFEEVIWTKFNSKDK------ 585

  Fly   672 LNYMDISANLAMKTNPEPERQRFWDEMYQH 701
             .|:.|.....::.|....:..||.|:..|
Zfish   586 -QYLHIGLKPRIRDNYRANKVAFWLELVPH 614

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10175	NP_001287487.1	COesterase	155..695	CDD:395084	174/618 (28%)
nlgn2a	XP_009301340.1	COesterase	47..608	CDD:395084	175/634 (28%)