Protein Alignment CG10175 and Nlg1

DIOPT Version :9

• Sequence 1: NP_001287487.1
• Gene: CG10175 / 42773
• FlyBaseID: FBgn0039084
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: NP_001246966.1
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Alignment Length: 708
• Identity: 186/708 - (26%)
• Similarity: 304/708 - (42%)
• Gaps: 167/708 - (23%)

  Fly    37 HRIIVTEQRKSSAEEAQEGYDPHGGDLQD---LRDKARAFYLIATTTTTSTTMSPEN-------- 90
            |:::........|.|.|..:  .|.:|::   ||:..:...:|...|   ||:.|::
  Fly    19 HKLLSHVSPMGVAAEKQPLH--KGNELENAMKLREAPKQSRVIGDIT---TTIQPDSDPGRSIGH 78

  Fly    91 ----ATKSENASGSLDMRQ----------MAHMG--SSTTETTA------------WKTLTSHPN 127
                ..|:...|..|..||          ..|:|  ::|..|||            ..:.|.||.
  Fly    79 QALRRAKAPPPSLELHFRQNLNKLFAGDETTHVGHTNATDNTTAAVLATDEGSSEHEPSTTHHPE 143

  Fly   128 SLVQLLPSRAMRVVQEVVRSLRKEREIVATTSLGKVRGRYQKYR--SGERGGYYSFKGMRYGAPP 190
            .. .::|.: ::..||:            ....|::.|..::::  ||.| ....|.|:.|...|
  Fly   144 RR-HVVPDK-LQYTQEI------------QVKQGRLMGITRRFQVTSGLR-QVDQFLGLPYAEAP 193

  Fly   191 TGARRFRAAEPEKPWSGIRDASREGQSCP------------------HKNM--ILDTFKGD-EDC 234
            ||.|||.......||.|::.|......||                  ||::  :|...:.: |||
  Fly   194 TGNRRFMPPGAPLPWQGLKIARHLPPVCPQKLPDLSPHGSENMSRARHKHLSRLLPYLRTESEDC 258

  Fly   235 LFVNVFTTQMPKDDESAEQPKLPVMVWLHGGGFSFGSGNSF------LYGPDYLVAEDIVLVTLN 293
            |::|::   :|.::..:...:..|:|:|||..|.:.|||.:      .||       ::::||:|
  Fly   259 LYLNLY---VPHEEPQSTPKQYAVLVYLHGESFEWNSGNPYDGSVLSSYG-------EVIVVTVN 313

  Fly   294 YRLGPLGFLTAGPDAP--GNQGLKDQVLALKWVRDNIAAFGGDPNQVTIFGESAGASSVQLLLLS 356
            ||||.||||....||.  .|..|.||:.||.|:::||.|||||.::||:.|.|.||:.|..|::|
  Fly   314 YRLGVLGFLRPSIDAHNIANYALLDQIAALHWIKENIEAFGGDNSRVTLMGHSTGAACVNYLMVS 378

  Fly   357 SQAKGLFHRAISQSGSALNPWSMSASSSQRAARLAANL-----GYVGANKTEDILDFLRRVPAMK 416
            ..|.|||||||..||||::.|:.|..|.|...::|..|     .:|.|...:.:||.||......
  Fly   379 PVASGLFHRAILMSGSAMSDWAASNQSLQLTMQIAHALECPLNEHVEAEDDDVLLDCLRHRRYQD 443

  Fly   417 LVEAAPTTITAEDQRNNIGLPFVPVVEGYW--NQDSQEEQFYEEPF--------LTQHPSDMYHS 471
            ::. .||.:|  ....::|    |:|:|:.  ||..:....|.|.|        :|:  |:.||
  Fly   444 ILH-IPTALT--QFSTSLG----PIVDGHVIPNQPYKVMGHYTEHFSRYDLLFGITE--SESYH- 498

  Fly   472 QNFNSDVAYMTGYNTHEAMLFIRRLRKNPQ---LLSIIENDFGRLVPQDLNVTESHDRVTREIRS 533
                          |..|:.....||:|.:   |...:::.|.  :..||.:..:    .::.:.
  Fly   499 --------------TLAALALEEGLRENERDNLLRFYMQSRFD--IRPDLALAAT----LKKYQD 543

  Fly   534 FYLGS-KHVGIESVDEMIALLTDLMFLQGIRRTARNHAKFGNAPVYMYRFSFDGSLGLYKRMLGI 597
            .|... |...:|..|.::.:|:|...:..:.:|...||.. |...|||.|..:.:.|.:..:
  Fly   544 MYNNPIKATNLEHRDVVLDILSDARVVGPLLQTGMFHADV-NRRNYMYVFGHNSATGPFAHL--- 604

  Fly   598 PRPGVCHGDELGYLF--------KFGFFNLSLDPKSMEVQVKNRMVRMWTNFAKYGSP 647
              |....|:||.::|        .|...|.::..|.:...|    :..||||.|.|:|
  Fly   605 --PHSIMGEELAFIFGAPLAAAGPFPSGNYTVQEKLLSEAV----MAYWTNFVKTGNP 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10175	NP_001287487.1	COesterase	157..695	CDD:278561	156/549 (28%)
Nlg1	NP_001246966.1	COesterase	153..710	CDD:278561	158/567 (28%)
		Aes	<263..>408	CDD:223730	63/154 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	98	1.000	Domainoid score	I1867
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm46967
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.810