Protein Alignment CG10175 and Nlg3

DIOPT Version :10

• Sequence 1: NP_001287487.1
• Gene: CG10175 / 42773
• FlyBaseID: FBgn0039084
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: NP_731170.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Alignment Length: 845
• Identity: 199/845 - (23%)
• Similarity: 309/845 - (36%)
• Gaps: 249/845 - (29%)

  Fly    15 ALSLAIGLIVMAICVQR--------PNESGHRIIVTEQRKSSAEEAQEGYDPHGGDLQDLRDKAR 71
            |||..:.|:|:.||:.|        .:.||:  :.|.|:..|:..       :||
  Fly    32 ALSSLLALVVLDICIARCLAAGISYSSNSGN--LSTSQKSPSSAN-------NGG---------- 77

  Fly    72 AFYLIATTTTTSTTMSPENATKSENASGSLDMRQMAHMGSSTTETTAWKTLTSHP-----NSLVQ 131
             ..||.:::.||:::...:.|.|.:|..|......:...|||:.:.:....:|.|     ||...
  Fly    78 -LVLIGSSSATSSSVPSLSLTSSSSAGLSSPGSSSSSSSSSTSTSGSNSNRSSRPTSNNSNSNSN 141

  Fly   132 LLPSRAMRVVQEVVRSLRKEREIVATTSLGKVRGRYQKYRSGERGGYYSFKGMRYGAPPTGARRF 196
            ..|:......|...|        :..|..|.:.|...:..........:::|:.|.:||.|..||
  Fly   142 YSPNHDQLPAQLSSR--------IINTRNGAISGVIVQLDGRHLDPVEAYRGIPYASPPVGNLRF 198

  Fly   197 RAAEPEKPWSGIRDASREGQSCPH-----------------------KNMILDTFKGDEDCLFVN 238
            ........|||::.|.|....||.                       |.::.......||||::|
  Fly   199 MPPVSAAMWSGVKKADRFSPVCPQRLPDIHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLN 263

  Fly   239 VFT-TQMPKDDESAEQ----------------------------------PKLPVMVWLHGGGFS 268
            ::. .|:...|.|...                                  .|.||:|::||..:.
  Fly   264 IYVPIQVGSRDSSGSSSSSSAGSSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYE 328

  Fly   269 FGSGNSF------LYGPDYLVAEDIVLVTLNYRLGPLGFLTAGPD----APGNQGLKDQVLALKW 323
            :.|||.:      .||       .|::||:|||||.||||.|..|    .|.|.||.|.:.||.|
  Fly   329 WNSGNPYDGSVLASYG-------QILVVTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHW 386

  Fly   324 VRDNIAAFGGDPNQVTIFGESAGASSVQLLLLSSQA--KG-LFHRAISQSGSALNPWSMSASSSQ 385
            :::||||||||||.:|:.|...||:.|. .|:||.|  :| ||:|||..|||.|.|||:.::.::
  Fly   387 LKENIAAFGGDPNSITLAGHGTGAACVH-FLISSMAVPEGLLFNRAILMSGSGLAPWSLVSNPAK 450

  Fly   386 RAA------RLAANLGYVGANK--TEDILDFLRRVPAM--------------------KLVEAAP 422
            .||      ..|::|.:....|  .|..||.|..||..                    ..|..||
  Fly   451 YAAIVAHHVNCASDLPHAHLMKCLREKTLDQLLSVPIRPPEFGFAFGPSIDGVVIDGGDYVPPAP 515

  Fly   423 TTITAEDQR-------NNIGLPFVPVVEGYWNQDSQEEQF-------------YE--------EP 459
            .:..|:.|.       |.:|........|.|....|.|..             |:        |.
  Fly   516 GSPAAQAQAQASTAAGNGLGGEAGIAAAGGWGTPGQLENIVLMRKTAINKLSRYDLMAGVTRAEA 580

  Fly   460 FLTQHPSDMYHSQNFNS-DVAYMTGYNTHEAMLFIRRLRKNP------QLLSIIEN---DFGRLV 514
            |.           :||| ||.|  |.........::...:|.      ::.:.|.|   |:.|.|
  Fly   581 FF-----------SFNSGDVQY--GIEADRRSRILKAYVRNTYTFHLNEIFATIVNEYTDWERPV 632

  Fly   515 PQDLNVTESHDRVTREIRSFYLGSKHVGIESVDEMIALLTDLMFLQGIRRTARNH-AKFGNAPVY 578
            ...:|:.                         ||.:..|:|...:....:|...| |...|:  |
  Fly   633 QHPINIR-------------------------DETLEALSDAQVVAPAAQTVDLHSADHRNS--Y 670

  Fly   579 MYRFSFDGSLGLYKRMLGIPRPGVCHGDELGYLFKF----GFFNLSLDPKSMEVQVKNRMVRMWT 639
            :|.|.:....|.|.:     |.|..||::|.|:|..    ||.:.:.:....|:.:...::..|:
  Fly   671 LYVFDYQTRFGDYPQ-----RQGCIHGEDLPYIFGAPLVGGFNHFTRNYTKTEISLSEVVMFYWS 730

  Fly   640 NFAKYGSPTPDSE---------DPMLTTKWAPIDPTNVMNSLNYMDISANLAMKTNPEPERQRFW 695
            ||.:.|:|....|         ....|.:|...:..:    ..|::......:|.:....|..||
  Fly   731 NFVRTGNPNEQMETEHGSRQERSRYKTIEWTAYESVH----KKYLNFDTKPKLKNHYRAHRLSFW 791

  Fly   696  695
              Fly   792  791

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10175	NP_001287487.1	COesterase	155..695	CDD:395084	164/690 (24%)
Nlg3	NP_731170.2	COesterase	154..791	CDD:395084	165/701 (24%)