DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10175 and Jhe

DIOPT Version :9

Sequence 1:	NP_001287487.1	Gene:	CG10175 / 42773	FlyBaseID:	FBgn0039084	Length:	707	Species:	Drosophila melanogaster
Sequence 2:	NP_001163166.1	Gene:	Jhe / 36780	FlyBaseID:	FBgn0010052	Length:	579	Species:	Drosophila melanogaster

Alignment Length:	533	Identity:	178/533 - (33%)
Similarity:	253/533 - (47%)	Gaps:	73/533 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   155 VATTSLGKVRG-RYQKYRSGERGGYYSFKGMRYGAPPTGARRFRAAEPEKPWSGIRDASREGQSC 218
            |...|:|.::| ..|.|:| ||  :.:|.|:.|..||.|..||...:......|:.|||.....|
  Fly    34 VCPPSVGCLKGTNLQGYQS-ER--FEAFMGIPYALPPIGDLRFSNPKVMPKLLGMYDASAPKMDC 95

  Fly   219 PHKNMILDT--FKGDEDCLFVNVFTTQMPKDDESAEQPKLPVMVWLHGGGFSFGSGNSFLYGPDY 281
            ..||.:|.|  ..||||||::||:..::.|.       .|||||::|||||..||....:.||:|
  Fly    96 IQKNYLLPTPVVYGDEDCLYLNVYRPEIRKS-------ALPVMVYIHGGGFFGGSAGPGVTGPEY 153

  Fly   282 LV-AEDIVLVTLNYRLGPLGFLTAGPDA--PGNQGLKDQVLALKWVRDNIAAFGGDPNQVTIFGE 343
            .: :.:::|||:.|||||.|||:. .||  .||.|||||.|||:||:.||..|||||.:|||||:
  Fly   154 FMDSGEVILVTMAYRLGPFGFLST-QDAVMSGNFGLKDQNLALRWVQRNIRFFGGDPQRVTIFGQ 217

  Fly   344 SAGASSVQLLLLSSQAKGLFHRAISQSGSALNPWSMSASSSQRAARL--------AANLGYVGAN 400
            |||..:..:.|||.::.|||||.||.||:|..|::::....::|..|        |.||..|...
  Fly   218 SAGGVAAHMHLLSPRSHGLFHRVISMSGTANVPFAIAEQPLEQARLLAEFADVPDARNLSTVKLT 282

  Fly   401 KTEDILDFLRRVPAMKLVEAAPTTITAEDQRNNIGLPFVPVVEGYWNQDSQ-------EEQFYEE 458
            |.      |||:.|.||:.|..            ||.       ||:.|..       ||....:
  Fly   283 KA------LRRINATKLLNAGD------------GLK-------YWDVDHMTNFRPVVEEGLEVD 322

  Fly   459 PFLTQHPSDMYHSQNFNSDVAYMTGYNTHEAMLFIRRLRKNPQLLSIIENDFGRLVPQDLNVTES 523
            .||..||.||. :|...:.:..:.|....|..:.:..:..|..|.......|..|:.:.|....|
  Fly   323 AFLNAHPMDML-AQGMPTSIPLLLGTVPGEGAVRVVNILGNETLRQSFNLRFDELLQELLEFPAS 386

  Fly   524 HDRVTRE------IRSFYLGSKHVGIESVDEMIALLTDLMFLQGIRRTARNHAKFGNAPVYMYRF 582
            ..:..||      :..::.|...|...:|...:.|::|..|.|.:..|...:......|||:|.|
  Fly   387 FSQDRREKMMDLLVEVYFQGQHEVNELTVQGFMNLISDRGFKQPLYNTIHKNVCHTPNPVYLYSF 451

  Fly   583 SFDGSL---GLYKRMLGIPRPGVCHGDELGYLFKFGFFNLSLDPKSMEVQVKNRMVRMWTNFAKY 644
            ::.|.|   ..|.......:.||.|.|:|.|||:...........|.|.:|.:..|..:.:|||:
  Fly   452 NYQGPLSYASAYTSANVTGKYGVVHCDDLLYLFRSPLLFPDFQRNSTEAKVIHSFVDYFVHFAKF 516

  Fly   645 GSP------TPDS 651
            |.|      ||.|
  Fly   517 GKPRNSESLTPCS 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10175	NP_001287487.1	COesterase	157..695	CDD:278561	177/531 (33%)
Jhe	NP_001163166.1	COesterase	40..527	CDD:278561	173/523 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	98	1.000	Domainoid score	I1867
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	99	1.000	Inparanoid score	I1664
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm46967
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
	8	7.960