DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10175 and CG4382

DIOPT Version :9

Sequence 1:	NP_001287487.1	Gene:	CG10175 / 42773	FlyBaseID:	FBgn0039084	Length:	707	Species:	Drosophila melanogaster
Sequence 2:	NP_609301.2	Gene:	CG4382 / 34279	FlyBaseID:	FBgn0032132	Length:	580	Species:	Drosophila melanogaster

Alignment Length:	589	Identity:	190/589 - (32%)
Similarity:	293/589 - (49%)	Gaps:	44/589 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   122 LTSHPNSLVQLLPSRAMRVVQEVVRSLRKEREIVATTSLGKVRGRYQKYRSGERGGYYSFKGMRY 186
            |.|..||...|  |:|:...::.:.|.::..::|.||:|||:||.....:||.  .:|:|:|:.|
  Fly    14 LASGQNSDEDL--SKAIPDEEDPIGSNKELSDLVITTALGKIRGTILPSQSGR--NFYAFRGIPY 74

  Fly   187 GAPPTGARRFRAAEPEKPWSGIRDASREGQSCPHKNMILDTFKGD--EDCLFVNVFTTQMPKDDE 249
            ..||....||:..||.:.|....||:.:|..||...::    .||  ||||.||::|.::|  .|
  Fly    75 AKPPVDRLRFQPPEPVEQWFDTLDATFDGPKCPQLGLV----SGDVSEDCLRVNIYTKELP--SE 133

  Fly   250 SAEQPKLPVMVWLHGGGFSFGSGNSFLY-GPDYLVAEDIVLVTLNYRLGPLGFLTAGP-DAPGNQ 312
            |....:.||:|::|.|||...||.|..: ||.|.:...:||||.|||||.||||..|. :||||.
  Fly   134 SQPNVRRPVIVFIHPGGFYSLSGQSKNFAGPQYFMNRRLVLVTFNYRLGSLGFLATGTREAPGNM 198

  Fly   313 GLKDQVLALKWVRDNIAAFGGDPNQVTIFGESAGASSVQLLLLSSQAKGLFHRAISQSGSALNPW 377
            ||||||..|:||:.:|:.|||||:.:|:.|..|||.:|.|.::|..::||||:||..||:....|
  Fly   199 GLKDQVQLLRWVKLHISRFGGDPSSITLLGYGAGAMAVTLHMVSPMSRGLFHKAIVMSGAVTGQW 263

  Fly   378 SMSASSSQRAARLAANLGYVGANKTEDILDFLRRVPAMKLVEAAPTTITAEDQRNNIGLPFVPVV 442
            |:.......|.:.|..|.....|.|| ::|.|:....::.....|...  |..|||..:.:.||:
  Fly   264 SLPDHQMDVATKQATLLHCHTENVTE-MMDCLKGKHYLEFANTLPKMF--EFDRNNPLILWKPVI 325

  Fly   443 EGYWNQDSQEEQFYEEPFLTQHPSDMYHSQNFNSDVAYMTGYNTHEAMLFIRRLRKNPQLLSIIE 507
                     |..|.:|.||.:.|...|.:.:| ..|..:||....|.:.....:.::|.|||.:.
  Fly   326 ---------EPDFGQERFLVEEPIRSYQNDDF-MKVPIITGMTKDEFVGPALSILQSPTLLSALN 380

  Fly   508 NDFGRLVPQDLNVTESHDR---VTREIRSFYLGSKHVGI-ESVDEMIALLTDLMFLQGIRRTARN 568
            .:|..|.|.......|..|   :::|:|:.|...|.:.. .|::.:..|.:|.:...||.|..
  Fly   381 ENFESLAPVFFMYNTSDARACNISQELRNHYFPDKLIDANRSLEALSNLYSDALTGFGIHRFV-- 443

  Fly   569 HAKFGNAPVYMYRFSFDGSLGLYKRMLGIPRP---GVCHGDELGYLFKFGFFNLSLDPKSMEVQV 630
            |....:..||.||||:.|:    :..:..|..   ||.|.|:|.|||.....:........|.::
  Fly   444 HLAARSTKVYYYRFSYQGA----RSHIYYPEDAPYGVVHHDDLMYLFVEPSISRMFTEDDDEFRM 504

  Fly   631 KNRMVRMWTNFAKYGSPTPDSEDPMLTTKWAPIDPTNVMNSLNYMDISANLAMKTNPEPERQRFW 695
            .:.||||::.||..|.|...::..:...:|.|..    .....|:||..::.::.|...|....|
  Fly   505 VDIMVRMFSAFAYKGDPNKPTDLALRDIRWRPFS----FKKRYYLDIGKHITLEENLNAENYEIW 565

  Fly   696 DEMY 699
            ..::
  Fly   566 KRLF 569

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10175	NP_001287487.1	COesterase	157..695	CDD:278561	180/548 (33%)
CG4382	NP_609301.2	COesterase	41..565	CDD:278561	181/554 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	98	1.000	Domainoid score	I1867
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	99	1.000	Inparanoid score	I1664
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm46967
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
	8	7.960