Protein Alignment CG10175 and Nlg3

DIOPT Version :10

• Sequence 1: NP_001287487.1
• Gene: CG10175 / 42773
• FlyBaseID: FBgn0039084
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: XP_061500330.1
• Gene: Nlg3 / 3290865
• VectorBaseID: AGAMI1_000316
• Length: 952
• Species: Anopheles gambiae
• Alignment Length: 717
• Identity: 184/717 - (25%)
• Similarity: 292/717 - (40%)
• Gaps: 163/717 - (22%)

  Fly    72 AFYLIATTTTTSTTMSPEN-----ATKSENASGSLDMRQMAHMGSSTTETTAWKTLTSHPNSLVQ 131
            |..:||....|.:.::|.|     ::.|.::|||.:.......||::.:..  :||..
Mosquito     4 ATVIIAVVVFTVSLVAPINSAGSGSSSSSSSSGSGNSPSNGGPGSNSMDEN--ETLKK------- 59

  Fly   132 LLPSRAMRVVQEVVRSLRKEREIVATTSLGKVRGRYQKYRSGERGGYYSFKGMRYGAPPTGARRF 196
               |.:.|:|.               |..|.|.|..:...........:|:|:.|.:||.|..||
Mosquito    60 ---STSSRIVH---------------TKYGAVSGTIEHLDGRHLDPVEAFRGVPYASPPVGNLRF 106

  Fly   197 RAAEPEKPWSGIRDASREGQSCPHK----------------------NMILDTFKG-DEDCLFVN 238
            ........|||::.|.|....||.:                      ..:|...:. .||||::|
Mosquito   107 MPPVTGALWSGVKKADRFSPVCPQRLPDIYNETAALERMPRGRLEYLRRLLPYLRNQSEDCLYLN 171

  Fly   239 VFTTQMPKDDESAEQPKLPVMVWLHGGGFSFGSGNSF------LYGPDYLVAEDIVLVTLNYRLG 297
            ::........||:...|..|:|::||..:.:.|||.:      .||       .|::||:|||||
Mosquito   172 IYVPTQAGSRESSSTSKYAVVVFVHGESYEWNSGNPYDGSVLASYG-------QILVVTINYRLG 229

  Fly   298 PLGFLTAGPD----APGNQGLKDQVLALKWVRDNIAAFGGDPNQVTIFGESAGASSVQLLLLSSQ 358
            .||||.|..|    ||.|.||.|.:.||.|:::||.||||||..||:.|...||:.|..|:.|:.
Mosquito   230 ILGFLNANVDRFSKAPANYGLMDIIAALHWIQENIEAFGGDPKSVTLAGHGTGAACVHFLIASAA 294

  Fly   359 A-KG-LFHRAISQSGSALNPWSMSASSSQRAARLAANLGYVGANKTED-----ILDFLRRVPAMK 416
            . :| ||||||..|||.|.|||:....::.||.::.::     |.:.|     :|..||..|
Mosquito   295 VPEGLLFHRAIMMSGSGLAPWSLVGEPAKFAAYVSHHV-----NCSPDLPHQLLLKCLRDKP--- 351

  Fly   417 LVEAAPTTITAEDQRNNIGLPFVPVVEGYWNQDSQEEQF----YEE----PFLTQHPSDMYHSQN 473
            |.:...|::.|.|    .|..|.|.|:|......:.:|.    |.:    |..|: ||...|:.
Mosquito   352 LEDILSTSVRAPD----FGNAFGPSVDGVVIDTGEIQQMDGTHYSDYSGNPAATK-PSAHIHNT- 410

  Fly   474 FNSDVAYMTGYNTHEAMLF----IRRLRKNPQLLSIIEND-FGRLVPQDLNVTESHDR------- 526
                      .||..|:|.    |.:|.|...|:.:...: :.....:|:......||
Mosquito   411 ----------LNTINAILLRKLAINKLSKYDLLVGVTRAEAYFAFNSEDVQYGIEADRRAKILKN 465

  Fly   527 VTREIRSFYLGS----------------KHVGIESVDEMIALLTDLMFLQGIRRTARNH-AKFGN 574
            ..|...||:|..                :| .|...||.:..|:|...:....:||..| |...|
Mosquito   466 YVRSTYSFHLNEILATIVNEYTDWERPVQH-PINIRDETLEALSDARIVAPAVQTADLHSADHRN 529

  Fly   575 APVYMYRFSFDGSLGLYKRMLGIPRPGVCHGDELGYLFKF----GFFNLSLDPKSMEVQVKNRMV 635
            :  ::|.|.:....|.:.:     |.|..||::|.|||..    ||.:.:.:....|:.:...::
Mosquito   530 S--FLYVFDYQTKFGDFPQ-----RQGCIHGEDLPYLFGAPLVGGFNHFTRNYTKSEIALSEAVM 587

  Fly   636 RMWTNFAKYGSPTPDSEDPML-------TTKWAPIDPTNVMNSLNYMDISANLAMKTNPEPERQR 693
            ..|:||.:.|:|....|:..:       ..:|.|.:..:    ..|:::.....:|.:....|..
Mosquito   588 IYWSNFIRTGNPNEQLENDHVRDRTRFKNIEWTPYESVH----KKYLNLDTKPKLKNHYRAHRLS 648

  Fly   694 FW 695
            ||
Mosquito   649 FW 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10175	NP_001287487.1	COesterase	155..695	CDD:395084	165/627 (26%)
Nlg3	XP_061500330.1	None