Protein Alignment CG10175 and Nlgn1

DIOPT Version :9

• Sequence 1: NP_001287487.1
• Gene: CG10175 / 42773
• FlyBaseID: FBgn0039084
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: XP_006535478.1
• Gene: Nlgn1 / 192167
• MGIID: 2179435
• Length: 863
• Species: Mus musculus
• Alignment Length: 649
• Identity: 182/649 - (28%)
• Similarity: 276/649 - (42%)
• Gaps: 152/649 - (23%)

  Fly   155 VATTSLGKVRGRYQKYRSGERGGYYSFKGMRYGAPPTGARRFRAAEPEKPWSGIRDASREGQSCP 219
            :.||:.||:||..::..:...|....|.|:.|.|||||..||:..||..|||.||:|::....||
Mouse    54 LVTTNFGKIRGIKKELNNEILGPVIQFLGVPYAAPPTGEHRFQPPEPPSPWSDIRNATQFAPVCP 118

  Fly   220 HKNMI----------------LDTFKG-----DEDCLFVNVFT-TQMPK---------------- 246
             :|:|                ||....     .||||::|::. |:..|
Mouse   119 -QNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDVKRISKECARKPGKKICR 182

  Fly   247 --------------DDESAEQ--------PKLPVMVWLHGGGFSFGSGNSFLYGPDYLVA-EDIV 288
                          |::.||.        || ||||::|||.:..|:||  ||....|.: .:::
Mouse   183 KGGPLTKKHTDDLGDNDGAEDEDIRDSGGPK-PVMVYIHGGSYMEGTGN--LYDGSVLASYGNVI 244

  Fly   289 LVTLNYRLGPLGFLTAGPD-APGNQGLKDQVLALKWVRDNIAAFGGDPNQVTIFGESAGASSVQL 352
            ::|:|||||.||||:.|.. |.||.||.|.:.||:|..:||..|||||.::|:||..||.|.|.|
Mouse   245 VITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNL 309

  Fly   353 LLL---------SSQAKGLFHRAISQSGSALNPWSMSASSSQRAARLAANLGYVGANKTEDILDF 408
            |.|         |:..||||.|||:|||:||:.|::|...::.|..||..:| ...:.|.::::.
Mouse   310 LTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARILATKVG-CNVSDTVELVEC 373

  Fly   409 LRRVPAMKLVEAAPTTITAEDQRNNIGLPFVPVVEGYWNQDSQEEQFYEEPFLTQHPSDMYHSQN 473
            |::.|..:||:       .:.|.....:.|.||::|....|..:....:..||
Mouse   374 LQKKPYKELVD-------QDVQPARYHIAFGPVIDGDVIPDDPQILMEQGEFL------------ 419

  Fly   474 FNSDVAYMTGYNTHEAMLFIRRLRKNPQLLSIIENDF--GRLVPQDLNVTESHDRVTREIRSFYL 536
             |.|:  |.|.|..|.:.|:..:..:...:|..:.||  ...|.......|..|.:...|:..|.
Mouse   420 -NYDI--MLGVNQGEGLKFVENIVDSDDGVSASDFDFAVSNFVDNLYGYPEGKDVLRETIKFMYT 481

  Fly   537 --GSKHVGIESVDEMIALLTDLMFLQGIRRTARNHAKFGNAPVYMYRFSFDGSLGLYKRMLGIPR 599
              ..:|........::||.||..::.....||..|:.|| :|.|.|.|        |........
Mouse   482 DWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFG-SPTYFYAF--------YHHCQTDQV 537

  Fly   600 PG---VCHGDELGY-----------LFKFGFFNLSLDPKSMEVQVKNRMVRMWTNFAKYGSPT-- 648
            |.   ..||||:.|           ||...|       ...:|.:...::..||||||.|.|.
Mouse   538 PAWADAAHGDEVPYVLGIPMIGPTELFPCNF-------SKNDVMLSAVVMTYWTNFAKTGDPNQP 595

  Fly   649 -----------PDSEDPMLTTKWAPIDPTNVMNSLNYMDISANLAMKTNPEPERQRFWDEMYQH 701
                       |:..:.:..|:::..|..       |:.|.....:|.:....:...|.|:..|
Mouse   596 VPQDTKFIHTKPNRFEEVAWTRYSQKDQL-------YLHIGLKPRVKEHYRANKVNLWLELVPH 652

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10175	NP_001287487.1	COesterase	157..695	CDD:278561	179/639 (28%)
Nlgn1	XP_006535478.1	COesterase	53..646	CDD:365897	179/641 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810