Protein Alignment CG10175 and cest-8

DIOPT Version :9

• Sequence 1: NP_001287487.1
• Gene: CG10175 / 42773
• FlyBaseID: FBgn0039084
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: NP_001359583.1
• Gene: cest-8 / 182818
• WormBaseID: WBGene00007691
• Length: 605
• Species: Caenorhabditis elegans
• Alignment Length: 616
• Identity: 141/616 - (22%)
• Similarity: 240/616 - (38%)
• Gaps: 164/616 - (26%)

  Fly   155 VATTSLGKVRGRYQKYRSGERGGYYSFKGMRYGAPPTGARRFRAAEPEK--PWSGIRDASREGQS 217
            :..||.||:||..:  .|.:....::||.:.:..||.|..||  |.|:|  .|.||.|||....:
 Worm    20 IINTSYGKLRGMAE--WSDDANHKFTFKSVPFAKPPIGNLRF--APPQKLDHWDGILDASVYSAA 80

  Fly   218 CPHKNMILDTFKGDEDCLFVNVFTTQMPKDDESAEQPKLPVMVWLHGGGFSFGSGNSF--LYGPD 280
            |...:.:......:||||::|:||:      |...:.|..|:|:.|||.::..|...|  .:..|
 Worm    81 CMSNSTLTTQSYVNEDCLYINIFTS------EKCLKSKCSVIVYFHGGAYNTESATMFSDRFILD 139

  Fly   281 YLVAEDIVLVTLNYRLGPLGFLTAGPDA--PGNQGLKDQVLALKWVRDNIAAFGGDPNQVTIFGE 343
            ..|.||::.|....|||..|.|..||:|  ..|..:.|.:|||.:|.:.|:.|||||.:|||.|.
 Worm   140 RYVHEDVIFVIPAVRLGVFGQLYFGPNAYLTENLFMFDAILALDFVHNEISNFGGDPEKVTIMGH 204

  Fly   344 SAGASSVQLLLLSSQAK---GLFHRAISQSGSALNPWSMSASSSQRAARLAANLGYVGANKTE-- 403
            |:|.:.|:.|..||...   .||.:.|..|.:.:  :.........:..:...||.....|.|
 Worm   205 SSGGTLVEALGFSSMVDPELKLFQQMIMLSSTGM--FGFDDLVIDNSFTIVEKLGCFNGTKEERN 267

  Fly   404 -----DILDFLRRVPAMKLVEAAPTTITAEDQRNNIGLPFVPVVEGYWNQDSQEEQFYEEPFLTQ 463
                 :.||.:|.:...:::. ....:...||     |.|..::.|             .||:.
 Worm   268 TVNVAETLDCMRHIDGYEILR-VQQKMELMDQ-----LSFKYLLRG-------------APFML- 312

  Fly   464 HPSDMYHSQNFNSDVAYMTGYNTHEAMLFIRRLRKNPQLLSIIENDFGRLVPQDLNVTESHDRVT 528
                      .|.::|               .|:||....:.|   ||....:..:|||.:..:|
 Worm   313 ----------LNGNIA---------------DLKKNTSPRNAI---FGTTEHEFFDVTEKYLYIT 349

  Fly   529 REIRSF---------YLGSKHVGIESVDEMIALLTDLMFLQGIRRTARNHAKFGNAPVYMYRFSF 584
            .....:         |.|..   :::::.||...:..:|:.    ||...|...||...::.|..
 Worm   350 VTFLDYENPVAVARNYDGRL---MKNMETMITGDSAAIFVS----TATCAAAMANAGADVFLFET 407

  Fly   585 DGSLGLYKRMLGIPRPGVCHGDELGYLFKFGFFNLSLDPKSMEVQVKNRMV-RMWTNFAKYGSPT 648
            ..|..:             |..::.|...    |.....:::::.:.:... ::.|||.|:|.|:
 Worm   408 RQSYSV-------------HVSDMQYFIG----NHCAHNRTIDIDILDSFYSKLLTNFTKHGKPS 455

  Fly   649 PDSEDPMLTTKWAPIDPTNVMNSLNYMDISANLAMKTNP-------------------------- 687
            |.         |.|:||    ..:||:::..:...::.|
 Worm   456 PG---------WDPVDP----GRMNYLELKVDSKARSGPVMLEGYHAKDVSFWVGEMTEFDQNVS 507

  Fly   688 --------EPERQ------RFWD-EMYQHYN 703
                    .||||      ::|: .:||:::
 Worm   508 KMRHSEGLPPERQDTKSQRQYWNFIVYQNFD 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10175	NP_001287487.1	COesterase	157..695	CDD:278561	138/603 (23%)
cest-8	NP_001359583.1	Abhydrolase	19..495	CDD:389770	134/571 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.900