Protein Alignment CG10175 and cest-30

DIOPT Version :10

• Sequence 1: NP_001287487.1
• Gene: CG10175 / 42773
• FlyBaseID: FBgn0039084
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: NP_504407.1
• Gene: cest-30 / 181871
• WormBaseID: WBGene00015071
• Length: 578
• Species: Caenorhabditis elegans
• Alignment Length: 600
• Identity: 172/600 - (28%)
• Similarity: 272/600 - (45%)
• Gaps: 99/600 - (16%)

  Fly   129 LVQLLPSRAMRVVQEVVRSLRKEREIVATTSLGKVRGRYQKYRSGER--GGYYSFKGMRYGAPPT 191
            ||.|.|.:..:::               ....|.:||...|:::|.:  .||.   |:.:...|.
 Worm    22 LVNLTPEKNSQIL---------------NAPCGPIRGNIYKHKNGTKIVDGYL---GIPFAKAPV 68

  Fly   192 GARRFRAAEPEKPWSGIRDASREGQSCPHKNMILD-TFK-----GDEDCLFVNVFTTQMPKDDES 250
            ||.:|:.....:.|:..||....|..||....... |.|     .:|:||.:|||..:.    :.
 Worm    69 GALKFKKPVAAEKWTEPRDCYEYGPGCPQTGRFAALTAKSTAAFAEENCLTLNVFAPRW----KL 129

  Fly   251 AEQPK-LPVMVWLHGGGFSFGSGNSFLYGPDY-----LVAEDIVLVTLNYRLGPLGFLT-AGPDA 308
            ||.|| |||:|:::|||:..|..:   |..||     |..:|:::||:||||||||||| |...|
 Worm   130 AEFPKGLPVLVYIYGGGYEIGFTS---YMDDYSLTGTLPLKDVIVVTMNYRLGPLGFLTIADGIA 191

  Fly   309 PGNQGLKDQVLALKWVRDNIAAFGGDPNQVTIFGESAGASSVQLLLLSSQAKGLFHRAISQSGS- 372
            .||.||.||.|||:||:||||:|||:|..||:.|.||||:|...|.||..:..||.|:||.||:
 Worm   192 NGNYGLWDQTLALQWVQDNIASFGGNPESVTLSGTSAGATSTDFLSLSPHSNQLFQRSISMSGTA 256

  Fly   373 ----ALNPWSMSASSSQRAARLAANLGYVGANKTEDILDFLRRVPAMKLVEAAPTTITAEDQRNN 433
                |:.|..:.....:..|:..   ||.|.: ::.:.|:.......|..|.|....||..
 Worm   257 FCNFAIRPKDVEVGVCKEFAQFQ---GYTGTD-SQSLFDWYMAQNVSKFKEVAGFQSTAAG---- 313

  Fly   434 IGLPFVPVVEGYWNQDSQEEQFYEEPFLTQHPSDMYHSQNFNSDVAYMTGYNTHEAMLFIRRLRK 498
             .:||:|..:|         .|:.:||      |:...:....| |.:|........:.|    .
 Worm   314 -AVPFIPNFDG---------DFFPKPF------DILRREAPKKD-ALITVVTMESVGMII----F 357

  Fly   499 NPQLLSIIENDFGRLVPQDL--NVTESHDRVTREIRSFYLGSKHVGIESV--DEMIALLTDLMFL 559
            || |.:...|:|...:.:..  :||:.:..|.:::..|||...:...::.  ..::..::|.:|.
 Worm   358 NP-LFANAYNNFEGFINETYGPDVTDYYADVKKKLTGFYLKDVNASDKATVNRRVVDYVSDSVFN 421

  Fly   560 QGIRRTARNHAKFGNAPVYMYRFSF--DGSLGLYKRMLGIPRP--GVCHGDELGYLFKFGFFNLS 620
            .|.....:::.|:|| .||:..|::  |.:    |.|:.:.:|  ...|..:..|.|..|.. .:
 Worm   422 SGTLDAVKSYVKYGN-KVYLGSFNYFNDAT----KDMVELMQPFKEASHSSDFKYYFGSGVM-AN 480

  Fly   621 LDPKSMEVQVKNRMVRMWTNFAKYGSPTPDSEDPMLTTKWAP--IDPTNVMNSLNYMDISANLAM 683
            ..|...|::|.:....:..||.|||.|...|.    |..|.|  |...|:...::|    ....|
 Worm   481 FTPTDEEMEVMDMSGTLMANFVKYGDPNGKSG----TKPWKPYTILKPNMYYKIDY----PTCEM 537

  Fly   684 KTNPEPERQRFWDEM 698
            ..|.:..|.|.:|::
 Worm   538 SDNFQNGRLRIYDDI 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10175	NP_001287487.1	COesterase	155..695	CDD:395084	167/569 (29%)
cest-30	NP_504407.1	COesterase	30..547	CDD:395084	166/585 (28%)