Protein Alignment CG10175 and cest-2.3

DIOPT Version :10

• Sequence 1: NP_001287487.1
• Gene: CG10175 / 42773
• FlyBaseID: FBgn0039084
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: NP_506510.2
• Gene: cest-2.3 / 179918
• WormBaseID: WBGene00013873
• Length: 665
• Species: Caenorhabditis elegans
• Alignment Length: 582
• Identity: 149/582 - (25%)
• Similarity: 231/582 - (39%)
• Gaps: 108/582 - (18%)

  Fly   159 SLGKVRGRYQKYRSGERGGYYS--FKGMRYGAPPTGARRFRAAEPEKPWSGIRDASREGQSCPHK 221
            |.|.:.|:.........|...:  |.|:.|..||.|..|||.....|.|.|:.:......:|  .
 Worm    23 STGTIEGKILNATYSPFGNQTATVFLGIPYVEPPIGELRFRKPRLLKSWEGVLETKDYKPAC--M 85

  Fly   222 NMILDTFKG------DEDCLFVNVFTTQMPKDDESAEQPKLPVMVWLHGGGFSFGSGNSF----- 275
            :....|||.      .||||:.||||.|....:::..     ||:.:|||.....||::|
 Worm    86 SYWRKTFKNGFVGEISEDCLYANVFTNQYCLQNKNCS-----VMIVVHGGRLVCESGSAFKPEIF 145

  Fly   276 ---LYGPDYLVAEDIVLVTLNYRLGPLGF-LTAGPDAPGNQGLKDQVLALKWVRDNIAAFGGDPN 336
               ..|.|    .:||:||.|||||..|| :..|.....|..:.|.:.|:||||..|..|||:.:
 Worm   146 INNFVGQD----RNIVVVTFNYRLGVFGFGVFNGETGDTNVAMYDMLEAVKWVRKEIDQFGGNKD 206

  Fly   337 QVTIFGESAGASSVQLLLLSSQAKGLFHRAISQSGSALNPWSMSAS------SSQRAARLAANLG 395
            ::|:.|.||||..:.....|:.:|||.|:.|..| :.|...|.||:      .:|....:....|
 Worm   207 RITMAGHSAGAGLIVDFTSSTLSKGLLHQQIVMS-APLQDISKSANFKGMTIVAQNVGCIPKEYG 270

  Fly   396 YVGANKTEDILDF--LRRVPAMKLVEAAPTTITAEDQRNNIGLPFVPVVEGYWNQDSQEEQFYEE 458
            :...:||:....:  |:...|..|:.|..:.     |:|:......|.|:|
 Worm   271 FRKLSKTQINKTYLCLQNKSAQDLLHAQLSM-----QQNSTFYFGSPRVDG-------------- 316

  Fly   459 PFLTQHPSDMYHSQNFNS--DVAYMTGYNTHEA--MLFI---RRLRKNPQLLSIIENDFGRLVPQ 516
            .|:|.:|.:::   |||:  .:....|..|.|.  .|:|   :..|...|||..:....|
 Worm   317 DFITDYPDNLF---NFNTIYPINTFIGTTTGELRDSLYITDPKNDRIKEQLLKNMCEHVG----- 373

  Fly   517 DLNVTESHDRVTREIRSFYLGSKHVGIESVDEMIALLTDLMFLQGIRRTARNHAKFGNAPVYMYR 581
             ..:.|..:..|::..::|        ::..:...|..|:.|..|..:.|..| |..|:.|:||.
 Worm   374 -YELFEKPEEFTKKCGNYY--------KNGTDAQFLSDDMEFYSGAIKVANAH-KRANSKVFMYS 428

  Fly   582 FSFDGSLGLYKRMLGIPRPGVCHGDELGYLFKFGFFNLSLDPKSMEVQVKNRMVR-MWTNFAKYG 645
            :.:.|:...:.:.|..|.|.  |.::|.|.     |..|..|...:..|..|:.. |..||..:.
 Worm   429 YDYKGAGTAFHKYLEAPSPH--HSEDLIYT-----FGTSRGPFVAKDYVIERIYSGMLANFINFE 486

  Fly   646 SPTPDSEDPMLTTKWAPIDPTNVMNSLNYMDISANLAMKTNPEPERQRFWDEMYQHYNGAAM 707
            .|:|..     |.:|...  |........:|...|..|            ..|..||...|:
 Worm   487 DPSPSK-----TQQWRQY--TQEKREYFLIDFDKNFTM------------PGMKDHYYTRAL 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10175	NP_001287487.1	COesterase	155..695	CDD:395084	145/568 (26%)
cest-2.3	NP_506510.2	alpha/beta hydrolases	17..532	CDD:473884	149/582 (26%)