Protein Alignment CG10175 and cest-2.1

DIOPT Version :9

• Sequence 1: NP_001287487.1
• Gene: CG10175 / 42773
• FlyBaseID: FBgn0039084
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: NP_506508.2
• Gene: cest-2.1 / 179916
• WormBaseID: WBGene00013875
• Length: 675
• Species: Caenorhabditis elegans
• Alignment Length: 590
• Identity: 150/590 - (25%)
• Similarity: 236/590 - (40%)
• Gaps: 112/590 - (18%)

  Fly   159 SLGKVRGRYQKYRSGERGGY--YSFKGMRYGAPPTGARRFRAAEPEKPWSGIRDASREGQSC--- 218
            |.|.:.|:.........|.:  ..|.|:.:..||.|..|||...|..||.||.:......:|
 Worm    24 STGTIEGKILTSTYSPLGNHTGIGFLGIPFVEPPAGNLRFRKPRPPIPWDGILETKEYKPACMSD 88

  Fly   219 ---PHKNMILDTFKGDEDCLFVNVFTTQMPKDDESAEQPKLPVMVWLHGGGFSFGSGNSFLYGPD 280
               .:||.:....  .||||:.||||.|.     ..::....||:.:|||.....|.::|  .|:
 Worm    89 AKKTYKNGVGGPI--SEDCLYANVFTNQY-----CMKRKNCSVMIVVHGGRILTESASAF--NPE 144

  Fly   281 YLV------AEDIVLVTLNYRLGPLGF-LTAGPDAPGNQGLKDQVLALKWVRDNIAAFGGDPNQV 338
            .||      ..:||:||.|||||..|| :..|.....|.|:.|.:.|:||.|..:..|||:.:::
 Worm   145 ILVNNFVGQGRNIVVVTFNYRLGTFGFGVLNGEKGDSNVGMFDMLEAVKWTRKEVHNFGGNKDKL 209

  Fly   339 TIFGESAGASSVQLLLLSSQAKGLFHR------AISQSGSALNPWSMSASSSQRAARLAANLGY- 396
            |:.|.|||.|.|.....|..:||:.::      |:.|.|...|...|:| .:|:|..|....|:
 Worm   210 TMVGHSAGGSLVGAFTSSPLSKGMLNQQIIMSGALYQMGKLANFKGMTA-MAQKAGCLPEVFGFR 273

  Fly   397 ----VGANKTEDILDFLRRVPAMKLVEAAPTTITAEDQRNNIGLPFVPVVEGYWNQDSQEEQF-- 455
                |..:||   ...||.:.|.::::|....:     :|......||.::|         :|
 Worm   274 KLSQVRIDKT---YSCLRNISAQEVLDAQLWVL-----QNTTYYISVPHIDG---------EFLL 321

  Fly   456 -YEEPFL---TQHPSDMYHSQNFNSDVAYMTGYNTHEAM--LFIRRLR---KNPQLLSIIENDFG 511
             |.:..|   |.||        .||    |.|..|.|..  ::|..|:   |..:||..:....|
 Worm   322 NYSDEILASGTIHP--------INS----MIGTTTAELRDPIYINDLKNADKKEELLKNLCEHIG 374

  Fly   512 RLVPQDLNVTESHDRVTREIRSFYLGSKHVGIESVDEMIALLTDLMFLQGIRRTARNHAKFGNAP 576
                  ..:....:..:|:.:.||        .:.|:...|..|:.|..|..:.|..||. .|..
 Worm   375 ------YELYTEPEEFSRKCQKFY--------GNGDDAQFLADDMEFYDGSIKVANAHAS-KNTK 424

  Fly   577 VYMYRFSFDGSLGLYKRMLGIPRPGVCHGDELGYLFKFGFFNLSLDPKSMEVQVKNRMVRMWTNF 641
            |:||.:.:..:...:|:....|.|.  |.::|.|:|.....|.:    ..:..::.....|:.:|
 Worm   425 VFMYSYDYKDAGPAFKKYAQAPPPH--HSEDLIYVFGTSRGNFT----EKDYVIEQIYSGMFADF 483

  Fly   642 AKYGSPTPDSEDPMLTTKWAPIDPTNVMNSLNYMDISANLAMKTNPEPERQR---FWD-----EM 698
            ..:|:|:|..|.     ||....|..  .....:|...|..|....:....|   ||.     ..
 Worm   484 VNFGNPSPSKEQ-----KWKEYSPEK--REYFLIDFDKNFTMPGTRDGYYSRALEFWSTAGTKSF 541

  Fly   699 YQHYN 703
            .:||:
 Worm   542 SEHYS 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10175	NP_001287487.1	COesterase	157..695	CDD:278561	146/575 (25%)
cest-2.1	NP_506508.2	COesterase	21..533	CDD:365897	146/575 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910