Protein Alignment CG10175 and cest-1.1

DIOPT Version :10

• Sequence 1: NP_001287487.1
• Gene: CG10175 / 42773
• FlyBaseID: FBgn0039084
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: NP_506506.1
• Gene: cest-1.1 / 179915
• WormBaseID: WBGene00011362
• Length: 673
• Species: Caenorhabditis elegans
• Alignment Length: 571
• Identity: 142/571 - (24%)
• Similarity: 236/571 - (41%)
• Gaps: 95/571 - (16%)

  Fly   159 SLGKVRGRYQKYRSGERGGYYS--FKGMRYGAPPTGARRFRAAEPEKPWSGIRDASREGQSC--- 218
            |.|.:.|:.........|...:  |.|:.:..||.|..|:|...|.|.|.|:...:....:|
 Worm    22 SSGTIEGKILNISYSPLGNQSATVFLGIPFVEPPIGDLRYRKPRPPKSWEGVLVTNEYKSACMSN 86

  Fly   219 ---PHKNMILDTFKG--DEDCLFVNVFTTQMPKDDESAEQPKLPVMVWLHGGGFSFGSGNSFLYG 278
               .:||    .|.|  .||||::||.|     ::...|.....||:.:||||:...|.::|  .
 Worm    87 ATKTYKN----KFGGPISEDCLYLNVLT-----NEYCLENKNCSVMMIVHGGGYLTESASTF--N 140

  Fly   279 PDYLV------AEDIVLVTLNYRLGPLGF-LTAGPDAPGNQGLKDQVLALKWVRDNIAAFGGDPN 336
            |:.|:      ..:||:||.|||||...| ...|.....|.||.|.:.::.|||..|..|||:.|
 Worm   141 PEILINNFVGQGRNIVVVTFNYRLGLFSFGQFNGDRGDKNFGLYDMIESVNWVRREIENFGGNKN 205

  Fly   337 QVTIFGESAGASSVQLLLLSSQAKGLFHRAISQSGSALNPWSMSASS--------SQRAARLAAN 393
            ::|:.|.|||||.:.....|...|||.|:.|..|....|   ||..|        :|....|:..
 Worm   206 RITLAGHSAGASMIVAFTSSPLTKGLVHQQIIMSAPMTN---MSKKSNFKGMTVMAQMVGCLSEE 267

  Fly   394 LGY--VGANKTEDILDFLRRVPAMKLVEAAPTTITAEDQRNNIGLPFVPVVEGYWNQDSQEEQFY 456
            :|:  :...:.|:....||:..|.::::|....:  ::....:|.|  |:
 Worm   268 IGFNKLSEEQVENTYSCLRKKSAQQILDAQLWLL--QNSTYFLGAP--PI--------------- 313

  Fly   457 EEPFLTQHPSDMYHSQN---FNSDVAYMTGYNTHEAMLFI--RRLRKNPQLLSIIENDFGRLVPQ 516
            :|.|||.:|.::|.|::   .|:.:. .|.....|:...|  ....|..:||..:.:..|.:
 Worm   314 DEHFLTDYPENLYASKSIYPINTLIG-TTTLEVEESSYIIDPAFADKKVELLENLCDHIGYV--- 374

  Fly   517 DLNVTESHDRVTREIRSFYL-GSKHVGIESVDEMIALLTDLMFLQGIRRTARNHAKFGNAPVYMY 580
               :.|..:..:::.:..|: |:..:.:.:..|......|.         |.:|.. ||..|::|
 Worm   375 ---LYEEPETFSKKCQKQYMNGNSSMNLSNEMEFYTPAIDF---------ADSHTS-GNTKVFLY 426

  Fly   581 RFSFDGSLGLYKRMLGIPRPGVCHGDELGYLFKFGFFNLSLDPKSMEVQVKNRMVRMWTNFAKYG 645
            .:.:.|:...|.|.|.:..|.  |.::|.|:  ||.......||  :..::.....|:.:|..:.
 Worm   427 SYDYRGAGPAYDRYLEVRSPH--HSEDLIYV--FGTHRGIFAPK--DYIIEKIYSGMFADFVNFE 485

  Fly   646 SPTPDSEDPMLTTKWAPIDPTNVMNSL-NYMDISANLAMKTNPEPERQRFW 695
            :|.|..:.     ||......|..:.| |:........|:.|...|...||
 Worm   486 NPLPSGDQ-----KWNQYTKENREHFLINFDKNFITPGMRDNYYTEAYEFW 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10175	NP_001287487.1	COesterase	155..695	CDD:395084	140/569 (25%)
cest-1.1	NP_506506.1	COesterase	19..531	CDD:395084	140/569 (25%)