Protein Alignment CG10175 and cest-1.2

DIOPT Version :9

• Sequence 1: NP_001287487.1
• Gene: CG10175 / 42773
• FlyBaseID: FBgn0039084
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: NP_506504.2
• Gene: cest-1.2 / 179914
• WormBaseID: WBGene00011364
• Length: 676
• Species: Caenorhabditis elegans
• Alignment Length: 564
• Identity: 149/564 - (26%)
• Similarity: 236/564 - (41%)
• Gaps: 122/564 - (21%)

  Fly   180 SFKGMRYGAPPTGARRFRAAEPEKPWSGIRDASREGQSCPHKNMILDTFKG-------DEDCLFV 237
            :|.|:.|..||.|..|||...|:|.|||:.:..:...:|...:  ..|:|.       .||||::
 Worm    47 AFLGIPYVEPPIGDLRFRKPRPQKTWSGVLETKKFKPACMSNS--TKTYKNGGIGGPISEDCLYL 109

  Fly   238 NVFTTQMPKDDESAEQPKLPVMVWLHGGGFSFGSGNSF--------LYGPDYLVAEDIVLVTLNY 294
            ||.|.|.     ..|.....|::.:||||:.|.|..:|        ..|.|    .:||:||:||
 Worm   110 NVLTNQY-----CLENKNCSVVIIVHGGGYLFESAATFNHEILVNNFVGQD----RNIVVVTINY 165

  Fly   295 RLGPLGF-LTAGPDAPGNQGLKDQVLALKWVRDNIAAFGGDPNQVTIFGESAGASSVQLLLLSSQ 358
            |||..|| ...|.:...|.|:.|.:.|:||||..|..|||:.:::|:.|.||||..|....:|..
 Worm   166 RLGIFGFGHLNGFEGDKNVGIFDTLEAVKWVRREIKQFGGNKDRITLAGHSAGAGVVAAFTISPL 230

  Fly   359 AKGLFHRAISQSGSALNPWSMSASSSQR-----AARLAANLGYVGANK-----TEDILDFLRRVP 413
            .|||.|:.|..||...|   ||..|:.:     |.|:..:....|.||     .|.:...||:.|
 Worm   231 TKGLIHQQIVMSGPMTN---MSKKSNFKGMTAMAERVGCHSKKYGFNKLPEHEVEQVYSCLRKKP 292

  Fly   414 AMKLVEAAPTTITAEDQRNNIGLPFVPVVEGYWNQDSQEEQFYEEPFLTQHPSDMYHSQNFNS-- 476
            |.:|::|....:     :|:......|.|:|              .|:|.:|.::|..::..|
 Worm   293 AQELLDAQLWLL-----QNSTFYFGAPPVDG--------------EFITDYPDNLYSEKSIFSIN 338

  Fly   477 -----------DVAYMTGYN-----THEAMLFIRRLRKNPQLLSIIENDFGRLVPQ-DLNVTESH 524
                       |..|::..|     |.|..|      ||             |..| .:.:.:..
 Worm   339 TLLGTTTRELQDTGYISNSNYSKFETKETFL------KN-------------LCDQIGIEIYKES 384

  Fly   525 DRVTREIRSFYLGSKHVGIESVDEMIALLTDLMFLQGIRRTARNHAKFGNAPVYMYRFSFDGSLG 589
            :..:.:.:.:|:.    |.:|.    :|..|:.|.......|..||:.|. .||||.:::.|:..
 Worm   385 EDFSSKCQKWYIN----GSDSK----SLSDDMEFYTQAINLADAHARKGK-KVYMYSYAYSGAGP 440

  Fly   590 LYKRMLGIPRPGVCHGDELGYLFKFGFFNLSLDPKSMEVQVKNRMVRMWTNFAKYGSPTPDSEDP 654
            .:|:.:.:..|.  |.::|  ::.||.......||  :..::.....|:.:|..:..|:|.::.|
 Worm   441 AFKKYMKVKSPH--HSEDL--IYTFGTHRGVFAPK--DYVIEYIYSGMFADFINFEDPSPSTDQP 499

  Fly   655 MLTTKWAPIDPTNVMNSLNYMDISANL---AMKTNPEPERQRFW 695
                 |......|....|  :|...||   .||.|...:...||
 Worm   500 -----WLQYTKENKEYFL--VDFDQNLTMPGMKKNYYAKAYEFW 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10175	NP_001287487.1	COesterase	157..695	CDD:278561	147/562 (26%)
cest-1.2	NP_506504.2	COesterase	21..536	CDD:278561	147/562 (26%)
		Aes	<125..>250	CDD:223730	51/131 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.000