Protein Alignment CG10175 and cest-17

DIOPT Version :9

• Sequence 1: NP_001287487.1
• Gene: CG10175 / 42773
• FlyBaseID: FBgn0039084
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: NP_505114.1
• Gene: cest-17 / 179198
• WormBaseID: WBGene00019477
• Length: 571
• Species: Caenorhabditis elegans
• Alignment Length: 602
• Identity: 170/602 - (28%)
• Similarity: 253/602 - (42%)
• Gaps: 144/602 - (23%)

  Fly   157 TTSLGKVRG-RYQKYRSGERGGYYSFKGMRYGAPPTGARRFRAAEPEKPWSGI-RDASREGQSC- 218
            ||..|.:.| .::...:|.:  |:.|.|:|||.||....||:..||.:.|..| .||:....||
 Worm    25 TTPYGPIVGFEHKSTVTGSK--YHVFLGIRYGNPPDHIYRFQKPEPVEKWPHINHDATHFRASCI 87

  Fly   219 PH-KNMILDTFKGDEDCLFVNVFTTQMPKDDESAEQPKLPVMVWLHGGGFSFGSGNSFLY--GPD 280
            |. ::.:.:.....|||||:|:.|   |.|   |::.||||:|::|||||.||..:...|  ..|
 Worm    88 PSLRSELEEQVNYSEDCLFLNIVT---PPD---AKEKKLPVLVFIHGGGFQFGDTSMIGYQKAAD 146

  Fly   281 YLVAEDIVLVTLNYRLGPLGFLTAG-PDAPGNQGLKDQVLALKWVRDNIAAFGGDPNQVTIFGES 344
            ..|::||:.|::.||||||||.|.| .:.|||.||.||.|||:::.:.:..|||||:::|:.|.|
 Worm   147 NFVSKDIIFVSIQYRLGPLGFFTTGDSEIPGNMGLWDQTLALQFLHEVLPDFGGDPDRITLAGHS 211

  Fly   345 AGASSVQLLLLSSQAKGLFHRAISQSGSALNPWSMSASSSQRAARLAANLGYVGANKTE--DILD 407
            |||:||..||.|..:..||.:||..|||..:..::..:....:.:||...|....:..|  |.::
 Worm   212 AGAASVSALLYSPHSDHLFSQAIQLSGSIFSESNLDRNVVDDSRKLAKAAGCPQEDSKELRDCIE 276

  Fly   408 FLRRVPAMKLVEAAPTTITAEDQRNNIG--LP------FVPVVEGYWNQDSQEEQFYEEPFLTQH 464
             :|.|..:.            |...:||  ||      |.|    |:::|     |:
 Worm   277 -IRTVDELL------------DAMESIGELLPGPRTKKFHP----YFDKD-----FF-------- 311

  Fly   465 PSDMYHSQNFNSDVAYMTGYNTHEAMLFIRRLRKNPQLLSIIENDFGRLVPQDLNVTESHDRVTR 529
            |.|:............|.|..:.|:.|.:....|..:||.         ||::...|.|.|.:..
 Worm   312 PYDIEKMSRKAPKKRTMQGLVSLESGLSVLYPVKLAKLLG---------VPKESWSTYSKDNLVD 367

  Fly   530 EIRS---------------------FYLGSKHVGIES--VDEMIALLTDLMFLQGIRRTARNHAK 571
            .|||                     |||.....|..|  ::....||:||.:
 Worm   368 FIRSQVAVEQEFGTASARFSGLVEEFYLSGPMTGNSSFYLNAFANLLSDLQY------------- 419

  Fly   572 FGNAP--------------VYMYRFSFDGSLGLYKRMLGIPRPGVCHGDELGYLFKF-GFFNLSL 621
              |.|              .|:|...:|...   .:....|..|..|..||.|||.| |...:..
 Worm   420 --NIPTLHEVELKLQHGWDTYLYIIDYDSET---TKDPTHPIKGPFHASELRYLFNFNGMDTIPF 479

  Fly   622 DPKSMEVQVKNRMVRMWTNFAKYGSPTPDSEDPMLTTK---WAPIDPTNVMNSLNYMDISANLAM 683
            :.|  :.:.:|..|....||...|:|         :||   |..:..:...         |||.:
 Worm   480 NDK--DKKFENYFVNAIVNFINTGTP---------STKALLWPAVSKSQPF---------ANLLL 524

  Fly   684 KTNPEPERQRFWDEMYQ 700
            ...|..:.. |..|.|:
 Worm   525 NDKPSVQTS-FRQEAYE 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10175	NP_001287487.1	COesterase	157..695	CDD:278561	167/595 (28%)
cest-17	NP_505114.1	COesterase	20..542	CDD:278561	170/602 (28%)
		Aes	<109..>225	CDD:223730	58/121 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.810