Protein Alignment CG10175 and cest-24

DIOPT Version :9

• Sequence 1: NP_001287487.1
• Gene: CG10175 / 42773
• FlyBaseID: FBgn0039084
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: NP_504613.1
• Gene: cest-24 / 179017
• WormBaseID: WBGene00020891
• Length: 658
• Species: Caenorhabditis elegans
• Alignment Length: 638
• Identity: 186/638 - (29%)
• Similarity: 269/638 - (42%)
• Gaps: 142/638 - (22%)

  Fly   132 LLPSRAMRVVQEV-----------VRSLRKEREIVATTSLGKVRGRYQKYRSGERGGYYSFKGMR 185
            |||.:..||....           ::|.:.|..||.... |.:.|...|...|:....  |.|:.
 Worm    64 LLPIKKARVRTSSNQSNMGTCFSNLKSGKSENAIVRVQQ-GLLEGFRVKTAKGDLCDV--FHGIP 125

  Fly   186 YGAPPTGARRFRAAEPEKPWSGIRDASREGQSCPHKNM----ILDTFKGDEDCLFVNVFTTQMPK 246
            |..||.|..||:..:|.|.|.|||..::......||.|    .|.:....||||::|||..::.:
 Worm   126 YAEPPVGELRFQKPQPPKAWEGIRKCNKYPNRSIHKEMPWDKALPSANQSEDCLYLNVFAPKIRE 190

  Fly   247 DDESAEQPKLPVMVWLHGGGFSFGSGNSFLYGP--DYLVAEDIVLVTLNYRLGPLGFLTAGPD-A 308
            |      .|.||:.::||||:...|...:....  ..||:.:|::||.:||||.||||:.|.| .
 Worm   191 D------KKYPVLFYIHGGGYVMDSAERYTAKNICKLLVSREIIVVTFHYRLGFLGFLSTGDDVC 249

  Fly   309 PGNQGLKDQVLALKWVRDNIAAFGGDPNQVTIFGESAGASSVQLLLLSSQAKGLFHRAISQSGSA 373
            |||.||.|.:.|::||..||::|||||..:|:.|:||||::..||..|...||||.|.|...|::
 Worm   250 PGNYGLFDMLEAMRWVHANISSFGGDPENITLSGQSAGAAAADLLSFSPLTKGLFKRKIVMGGNS 314

  Fly   374 LNPWSMSASSSQR------AARLA--ANLGYVGANKTE---DILDFLRRVPAMKL--VEAAPTTI 425
            ...|:.:::...|      |.||.  ..|.|  |||.|   ||.:|...:|..||  ......||
 Worm   315 YCHWATTSNHDIREYCKKWAKRLGWKPQLNY--ANKREESVDIFNFFNGLPTSKLGMTMFFSNTI 377

  Fly   426 TAEDQRNNIGLPFVPVVEGYWNQDSQEEQFYEEPFLTQHPSDMYHSQNFNSDVAYMTGYNTHEAM 490
            ..|.|     ||..||::|              ..|   |.|:...:.....|..:.|...:||:
 Worm   378 FKECQ-----LPLAPVIDG--------------EIL---PHDLKVLRETQEHVPSLVGGGEYEAL 420

  Fly   491 LF-----IRRLRKNPQLLSIIENDFGRLVPQDLNVTESHDRVTREIRSFYLGSKHVGIESVDEMI 550
            ||     :|...|.              :...::|....:|::|        ||   ||::.|.:
 Worm   421 LFCAIGLLRGTEKE--------------INSAIDVLSRKNRLSR--------SK---IEAMTEKV 460

  Fly   551 -----ALLTD-----LMFLQGIRRTARNHAKF------GNAPVYMYRFSFDGSLGLYKRMLG--- 596
                 ||..|     :.|:|.|.....|:..:      ....|..|.:|||..   .|:|.|
 Worm   461 YGDSPALRADSKARKMFFVQLISDIFANYGNYRFMRDCQQRGVECYGYSFDHQ---SKQMWGWLQ 522

  Fly   597 --IPRPGVCHGDELGYLFKFGFFNLSLDPKSMEVQVKNRMVRMWTNFAKYGSPT-PDSEDPMLTT 658
              :|..|..|..||.|||...:.:..|.....:..|.......:|||.|:|:|. |:|:.|
 Worm   523 HVVPFTGGTHTSELSYLFDCNYMSAPLGMNKTDKVVSGMTADYFTNFVKFGTPNGPNSQLP---- 583

  Fly   659 KWAPIDPTNVMNSLNYMDISANLAMKTNPEPE---------RQRFWDEMYQHY 702
            ||..|.|.:     .:|.:     :...||||         .|.|.|.:...|
 Worm   584 KWERISPDD-----EHMKL-----ISIKPEPEMKTTVYGYRMQNFEDHLGMLY 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10175	NP_001287487.1	COesterase	157..695	CDD:278561	174/593 (29%)
cest-24	NP_504613.1	COesterase	97..608	CDD:278561	175/585 (30%)
		Aes	<183..>285	CDD:223730	44/107 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H71115
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm14771
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.910