Protein Alignment CG10175 and cest-35.2

DIOPT Version :10

• Sequence 1: NP_001287487.1
• Gene: CG10175 / 42773
• FlyBaseID: FBgn0039084
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: NP_504398.1
• Gene: cest-35.2 / 178910
• WormBaseID: WBGene00016863
• Length: 544
• Species: Caenorhabditis elegans
• Alignment Length: 601
• Identity: 173/601 - (28%)
• Similarity: 258/601 - (42%)
• Gaps: 124/601 - (20%)

  Fly   148 LRKEREI-VATTSLGKVRGRYQKYRSGER--GGYYSFKGMRYGAPPTGARRFRAAEPEKPWSGIR 209
            |:.|:.. |...|.|.:||..  |..|::  .||.   |:.:...|.|..||:.:...:.|:...
 Worm     8 LKPEKNTEVFNASCGPIRGNV--YEHGDKIVNGYL---GIPFAKAPIGDLRFKKSVEAEKWTQPL 67

  Fly   210 DASREGQSCPHKN-----MILDTFKGD---EDCLFVNVFTTQMPKDDESAEQPK-LPVMVWLHGG 265
            |..:.|..||...     |:......|   ::||.:|||..:.    :|||.|. .||||:.:||
 Worm    68 DCYKYGPGCPQSAALGALMVSQATNHDFAEDNCLNLNVFAPKW----KSAEFPNGFPVMVYFYGG 128

  Fly   266 GFSFGSGNSFLYGPDY-----LVAEDIVLVTLNYRLGPLGFLTAGPD-APGNQGLKDQVLALKWV 324
            ||..|..:.|   .||     |..:|::|||.|||:|||||...|.| |.||.||.||.|||:||
 Worm   129 GFEVGFSSMF---DDYSLTGTLPLKDVILVTPNYRIGPLGFFATGDDVARGNWGLWDQALALQWV 190

  Fly   325 RDNIAAFGGDPNQVTIFGESAGASSVQLLLLSSQAKGLFHRAISQSGSALNPWSMSASSSQRA-- 387
            :.:|.:|||||:.|||.|.|||.:||..|.||..|...|.:.|..||:|..|:.:.:...:..
 Worm   191 QKHIKSFGGDPSNVTISGTSAGGASVDFLSLSPHANKYFQKFIPMSGAATCPFGIRSKDVEGLIF 255

  Fly   388 ARLAANLGYVGANKTEDILDFLRRVPAMKLVEAAPTTITAEDQRNNIGLPFVPVVEGYWNQDSQE 452
            ...|.:.||.| |.::.:|.:.:...:...::|......|...     ..|||..:|
 Worm   256 REFANHHGYTG-NDSKSLLQWYQSQDSEIFLKAEGYKCPASGM-----FSFVPNFDG-------- 306

  Fly   453 EQFYEEPFLTQHPSDMYHSQNFNSDVAYMTGYNTHEAMLFIRRLRKN-PQLLSIIE--------- 507
             .|:.:||                                 ..|||. |:|.:|:.
 Worm   307 -DFFPKPF---------------------------------DELRKEAPKLGAIVSIGEYEGLGF 337

  Fly   508 NDF--GRLVPQDL-------NVTESHDRVTREIRSFYLGSKHVGIESVDE----MIALLTDLMFL 559
            .||  |:..||.:       .|..:.:.|.:.....||  |:.|.|:.:.    ::.:..|..|.
 Worm   338 EDFYAGQKTPQQMLSAALGPEVVRNREEVVKRAAESYL--KNGGNENEENIAKTLVEIFGDYYFS 400

  Fly   560 QGIRRTARNHAKFGNAPVYMYRFS-FDGSLGLYKRMLGIPRP--GVCHGDELGYLFKFGFFNLSL 621
            .|...|.|:..|:||. ||:|.|: |:.:..:   :.|..||  ...||.:|.|:|..|....|.
 Worm   401 VGAFDTVRSLVKYGNT-VYLYSFNYFNPNTPI---VFGKNRPFNAANHGSDLRYIFGEGTGEFSK 461

  Fly   622 DPKSMEVQVKNRMVRMWTNFAKYGSPTPDSEDPMLTTKWAPIDPTNVMNSLNYMDIS-ANLAMKT 685
            :.:    ||.:.|....|||||||:|....    ::..|   :..::.|...|..|. ....|..
 Worm   462 EDR----QVMDMMGTYHTNFAKYGNPNGKG----VSVPW---EKYSLDNPGRYFKIDYPKCEMAD 515

  Fly   686 NPEPERQRFWDEMYQH 701
            |....|.:..||:.:|
 Worm   516 NFLDGRHKIIDEVNEH 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10175	NP_001287487.1	COesterase	155..695	CDD:395084	168/585 (29%)
cest-35.2	NP_504398.1	COesterase	18..517	CDD:395084	165/575 (29%)