Protein Alignment CG10175 and cest-6

DIOPT Version :9

• Sequence 1: NP_001287487.1
• Gene: CG10175 / 42773
• FlyBaseID: FBgn0039084
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: NP_501070.1
• Gene: cest-6 / 177459
• WormBaseID: WBGene00020688
• Length: 583
• Species: Caenorhabditis elegans
• Alignment Length: 611
• Identity: 147/611 - (24%)
• Similarity: 233/611 - (38%)
• Gaps: 169/611 - (27%)

  Fly   144 VVRSLRKEREI-VATTSLGKVRGRYQKYRSGERGGYYSFKGMRYGAPPTGARRFRAAEPEKPWSG 207
            :|.|..|..|. |.|||||.:.|       .:.|.|.:||.:.:..||.|..||:.....:.|.|
 Worm    13 IVYSAYKSCEAGVITTSLGSING-------NQIGSYQTFKKIPFAKPPIGKLRFQKPMAAEKWEG 70

  Fly   208 IRDASREGQSCPHKNMILDTFKG-----DEDCLFVNVFTTQMPKDDESAEQPKLPVMVWLHGGGF 267
            |.:|:..|.:|...:   .|.|.     |||||.:|:|||     |.........|:.::|||..
 Worm    71 ILNATEYGPACMSNS---STSKSPQKWIDEDCLHINIFTT-----DTCLSSKNCSVVFYVHGGEL 127

  Fly   268 SFGSG----NSFLYGPDYLVAEDIVLVTLNYRLGPLGFLTAGPD--APGNQGLKDQVLALKWVRD 326
            .:.|.    :.:|:  |...:.|::||...:|||..........  ||.|..|.|.:|||::|:.
 Worm   128 VYDSAVMFEDKYLF--DTFSSRDVILVIPAFRLGLFSHFVVEDQNVAPNNLALYDILLALEFVKS 190

  Fly   327 NIAAFGGDPNQVTIFGESAGASSVQLLLLSSQAK---GLFHRAISQSGSALNPWSMSASSSQRAA 388
            .|..|||..::||.||.|.|...|.::..|::..   ..|.|.|..  |::|.|.......::..
 Worm   191 EIHNFGGSSDRVTAFGHSYGGHVVSVMAFSTEINTDLSYFQRVICM--SSVNVWDSLEFEIEKTM 253

  Fly   389 RLAANLGYVGANKTEDI-------------LDFLRRVPAMKLVEAAPTTITAEDQRNNIGLPFV- 439
            |.   :.|...:..:|:             ::.|:.:.:|:|:....   :.||:.:.|....|
 Worm   254 RF---IQYANCSVPQDLKSRMTSFEQDSYMMECLQDIDSMELLRIQR---SLEDEGHPIYSGLVL 312

  Fly   440 --PVVEGYWNQDSQEEQFYEEP-------FLTQHPSDMYHSQNFNSDVAYMTGY-NTHEAMLFIR 494
              |:::....||     |||:|       ..|....|.:|:.:   ::....|| |..|.....|
 Worm   313 REPLIQNVLVQD-----FYEKPKNIPTLTGCTYKELDKFHAYH---NIVETLGYENYKECDDKYR 369

  Fly   495 RLRKNPQLLSIIENDFGRLVPQDLNVTESHDRVTREIRSFYLGSKHVGIESVDEMIALL------ 553
            ..||           :||.   |||                   ||     .||...:|
 Worm   370 DDRK-----------YGRF---DLN-------------------KH-----ADETFGILAQTKLK 396

  Fly   554 TDLMFLQGIRRTARNHAKFGNAPVYMYRFSFDGSLGLYKRMLGIPR-PGVCHGDELGYLFKFGFF 617
            .|....:||             |.|.|.:|:             |: |.  |.|:|.|:.....|
 Worm   397 VDKQLDKGI-------------PTYFYEYSY-------------PKHPS--HTDDLSYIMGVHAF 433

  Fly   618 NLSLDPKSMEVQVKNRMVRMWTNFAKYGSPTPDSEDPMLTTKWAPIDPTNVMNSLNYMDISAN-- 680
                :....|:.:......|:.||.|:|.|....|             .:...:.:|.:...|
 Worm   434 ----EKDENEIHLAKSYQEMFMNFVKFGEPGGGFE-------------MSTFENSSYFNFYWNET 481

  Fly   681 ----LAMKTNPEPERQRFW-DEMYQH 701
                .:||||.|.|..::| .:|:::
 Worm   482 TGEKSSMKTNFEKEIIKYWLKDMFEY 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10175	NP_001287487.1	COesterase	157..695	CDD:278561	140/588 (24%)
cest-6	NP_501070.1	Abhydrolase	25..500	CDD:389770	141/590 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900