Protein Alignment CG10175 and cest-5.1

DIOPT Version :9

• Sequence 1: NP_001287487.1
• Gene: CG10175 / 42773
• FlyBaseID: FBgn0039084
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: NP_501022.3
• Gene: cest-5.1 / 177429
• WormBaseID: WBGene00015279
• Length: 580
• Species: Caenorhabditis elegans
• Alignment Length: 590
• Identity: 133/590 - (22%)
• Similarity: 223/590 - (37%)
• Gaps: 155/590 - (26%)

  Fly   154 IVATTSLGKVRGRYQKYRSGERGGYYSFKGMRYGAPPTGARRFRAAEPEKPWSGIRDASREGQSC 218
            ::..||.|.:.|       .|.|.|:.||.:.:..||.|..||:..|....|.|||.|...|.:|
 Worm    19 LIIHTSFGHLEG-------AEIGDYHLFKKIPFAKPPVGNLRFQKPEAAGKWDGIRSAIEYGPAC 76

  Fly   219 ---------PHKNMILDTFKGDEDCLFVNVFTTQMPKDDESAEQPKLPVMVWLHGGGFSFGSGNS 274
                     |.|.:       |||||.||:||::     :..:.....:.|::||||.::.|...
 Worm    77 MSNSSKTKSPQKWV-------DEDCLHVNIFTSK-----KCLKSRNCAIAVYIHGGGLTYDSAVM 129

  Fly   275 F----LYGPDYLVAEDIVLVTLNYRLGPLGFLTAGPD--APGNQGLKDQVLALKWVRDNIAAFGG 333
            |    |.  |..|..|::||...:|||.....|....  ||.|..|.|..|||::|:..|.:|||
 Worm   130 FNDTVLL--DTFVKRDVILVIPGFRLGIFSHFTVHNQNVAPNNLALYDITLALEFVKSEIHSFGG 192

  Fly   334 DPNQVTIFGESAGASSVQLLLLSSQAK---GLFHRAISQSGSALNPWSMSASSSQRAARLAANLG 395
            :..::|:||.|.|.....::..||:..   .||.:||..||                       |
 Worm   193 NSQKITLFGHSYGGGLASMMTFSSEINRDLSLFQQAIVMSG-----------------------G 234

  Fly   396 YVGANKTEDILDFLRRVPAMKLVEAAPTTITAEDQRNNIGLPFVPVVEGYWNQDSQEEQFYEEPF 460
            :.    .|::.|.:.  ...:.||.|..::..:.:|.              .:.||:|.:..:..
 Worm   235 FY----FEELKDHIE--GTKRFVEYANCSVPLKLERK--------------MERSQQEMYMMKCL 279

  Fly   461 LTQHPSDMYHSQNFNSDVAY--MTGYNTHEAMLF--IRR--LRKNPQLLSI-------------I 506
            ......::...|....|..|  ..|....|. ||  :::  |.|:|:.:.:             |
 Worm   280 QKLSGMELLRIQRLLEDKGYPDFGGVILREP-LFPDVKKFELLKSPKNIPMLTGCTNLEFDHESI 343

  Fly   507 ENDFGRLVPQDLNVTESHDRVTREIRSFYLGSKHVGIES----VDEMIALLTDLMFLQGIRRTAR 567
            :..||:.:..: |..|..::...::.|        |:|:    .|:...::..|       :...
 Worm   344 KVPFGKYLEFE-NPDECDEKYRNDVES--------GVENRGNHTDKTQGIILPL-------KLQI 392

  Fly   568 NHAKFGNAPVYMYRFSFDGSLGLYKRMLGIPRPGVCHGDELGYLFKFGFFNLSLDPKSMEVQVKN 632
            |:....|...|:|.:::             |:.| .|.|:|.|:.....|....:...:|...|:
 Worm   393 NNLLENNVTAYLYEYTY-------------PKHG-RHTDDLSYIMGVHAFEKDENEVHLEQVYKD 443

  Fly   633 RMVRMWTNFAKYGSPTPDSEDPMLTTKWAPIDPTNVMNSLNYMDISANLAMKTNPEPERQRFWDE 697
            .::    ||.|.|.|....|             .:..|...|.||..|  ..|...|..::::::
 Worm   444 MVI----NFIKLGEPGMGFE-------------KSEQNESTYFDIYWN--ETTGERPRMRKYFEK 489

  Fly   698 MYQHY 702
            ....|
 Worm   490 EVTDY 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10175	NP_001287487.1	COesterase	157..695	CDD:278561	132/578 (23%)
cest-5.1	NP_501022.3	Abhydrolase	19..495	CDD:389770	133/590 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900