Protein Alignment CG10175 and cest-25

DIOPT Version :9

• Sequence 1: NP_001287487.1
• Gene: CG10175 / 42773
• FlyBaseID: FBgn0039084
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: NP_497609.1
• Gene: cest-25 / 175390
• WormBaseID: WBGene00022178
• Length: 550
• Species: Caenorhabditis elegans
• Alignment Length: 571
• Identity: 159/571 - (27%)
• Similarity: 259/571 - (45%)
• Gaps: 72/571 - (12%)

  Fly   152 REIVATTSLGKVRGRYQKYRSGERGGYYSFKGMRYGAPPTGARRFRAAEPEKPWSGIRDASREGQ 216
            |:::  ||.|.:.|| :....||: ...:|:|:.|.|||.|..||...:|.:.|:.:|:....|.
 Worm    17 RQVL--TSYGPIEGR-RLIHEGEK-QVDAFQGIPYAAPPIGNLRFALPQPHEKWTEVRETKSFGA 77

  Fly   217 SCPHKNMILD--TFKGDEDCLFVNVFT-TQMPKDDESAEQPKLPVMVWLHGGGFSFGSGNSFLYG 278
            ....|:.:|.  |....||.|.:|:|| ...||::..     .||::::|||||.  |.::..||
 Worm    78 RGIQKDHVLSPKTSPQSEDNLTLNIFTPVWTPKNETG-----FPVILYIHGGGFV--SDSAHKYG 135

  Fly   279 P----DYLVAEDIVLVTLNYRLGPLGFLTAGPDA-PGNQGLKDQVLALKWVRDNIAAFGGDPNQV 338
            .    .:||.:|:|:||:.||||.|||.|.|..: |.|..|.|.|.|||||::||..|.||||.:
 Worm   136 DMSICQHLVTKDVVVVTIQYRLGFLGFWTTGDSSIPDNVALHDMVFALKWVKENIGLFNGDPNNI 200

  Fly   339 TIFGESAGASSVQLLLLSSQAKGLFHRAISQSGSALNPWSMSASSSQRAARLAANLGYVGANKTE 403
            |:.|:|||.:||..|.:|..::.||.:.|...|:|...|::...........|..:|......|.
 Worm   201 TLMGQSAGGASVDFLSISPVSRDLFQKVIPMGGNASCSWAIHPRPLNACRNRAQEIGVFDGMNTL 265

  Fly   404 DILDFLRRVPAMKLVEAAPTTITAEDQRNNIGLPFVPVVEGYWNQDSQEEQFYEEPFLTQHPSDM 468
            |.::.||.:||.|.  |:...:.|.|.:.:..|...|..:..:......|...|.|   ..|..:
 Worm   266 DWVEKLRELPADKF--ASALNMEAVDTKTDPELLIGPKYDNLFIPRPVMELRKEAP---MKPRLL 325

  Fly   469 YHSQNFNSDVAYMTGYNTHEAMLFIRRLRKNPQLLSIIENDFGRLVPQDLNVTESHDRVTREIRS 533
            ..:::.....|:. |.||           |:|  |..::.|...::.:.|...::.|...:.:..
 Worm   326 GCAKSEGLVFAFF-GLNT-----------KHP--LHAVQQDVSAILSEKLFPLKARDYQEKALEK 376

  Fly   534 FY-LGSKHVGIESVDEMIALLTDLMFLQGIRRTARNHAKF-GNAPVYMYRFSF-----DGSLGLY 591
            .. :|:.|...|....|:.|..|.....||::...:..:. .:.|:|||.|.:     .|.:| :
 Worm   377 LIEIGTDHSKEEWQRAMVDLKGDSFLNVGIQQNVLDVLETQPSTPIYMYSFDYCNPKAYGIMG-F 440

  Fly   592 KRMLGIPRPGVCHGDELGYLFKFGFFNLSLDPKSMEVQVKNRMVRMWTNFAKYGSPTPDSED-PM 655
            |    :|.....|..::.|:......| |.|....:.::.....|:||||||||:|..:.:| ..
 Worm   441 K----LPFKDATHCTDISYVVGNHIVN-SFDFNEEDYKMIEITTRLWTNFAKYGNPNGEGDDVAH 500

  Fly   656 LTTKWAPIDPTNVMNSLNYMDIS-----------------ANLAMKTNPEP 689
            |..||   :|..:.:...:|.::                 |.|..:..|.|
 Worm   501 LEEKW---EPATIESPQTHMALTLQPKLHHVYKQGRPLFMAKLLKEARPPP 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10175	NP_001287487.1	COesterase	157..695	CDD:278561	158/566 (28%)
cest-25	NP_497609.1	COesterase	18..536	CDD:365897	154/556 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	221	1.000	Domainoid score	I1491
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H71115
Inparanoid	1	1.050	221	1.000	Inparanoid score	I2278
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D222591at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm14771
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.770