Protein Alignment CG10175 and ace-4

DIOPT Version :9

• Sequence 1: NP_001287487.1
• Gene: CG10175 / 42773
• FlyBaseID: FBgn0039084
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: NP_496962.1
• Gene: ace-4 / 175074
• WormBaseID: WBGene00000038
• Length: 602
• Species: Caenorhabditis elegans
• Alignment Length: 640
• Identity: 182/640 - (28%)
• Similarity: 287/640 - (44%)
• Gaps: 151/640 - (23%)

  Fly   145 VRSLRKEREIVATTSLGKVRGR-----YQKYRSGERGGYYSFKGMRYGAPPTGARRFRAAEPEKP 204
            :.|::....:|..|.||.::|.     .:|.|        :|.|:.:..|.....|||....:|.
 Worm    18 IDSVQAVHPVVLETKLGDIKGTEFFFLSKKIR--------TFFGVPFAEPAVEDFRFRKPREKKQ 74

  Fly   205 WSGIRDASREGQSC-PHKNMILDTFKG----------DEDCLFVNVFTTQMPKDDESAEQPKLPV 258
            |.|:.||::...:| ..::....:|.|          .||||::|::.        .|:...|.|
 Worm    75 WRGLYDATKPANACFQTRDNYNTSFWGSEMWNANTQISEDCLYLNIWA--------PADAYNLTV 131

  Fly   259 MVWLHGGGFSFGSGNSFLY-GPDYLVAEDIVLVTLNYRLGPLGFLTAG-PDAPGNQGLKDQVLAL 321
            |||..||||..||.:..:| |......:::::|.:||||||.|||..| ||||||.||.||.|||
 Worm   132 MVWFFGGGFYSGSPSLSIYDGKALTSTQNVIVVNINYRLGPFGFLYLGHPDAPGNMGLLDQQLAL 196

  Fly   322 KWVRDNIAAFGGDPNQVTIFGESAGASSVQLLLLSSQAKGLFHRAISQSGSALNPWSMSA--SSS 384
            .|||.||.:|||:|::|.:||:||||:|:...|::..::|||..||.||||..|.|::::  .:.
 Worm   197 HWVRQNIVSFGGNPDKVAVFGQSAGAASIVAHLIAPGSRGLFKNAILQSGSLENTWAINSPFRAK 261

  Fly   385 QRAARLAANLGYVGANKTEDILDFLRRVPAMKLVEAAPTTITAEDQRNNIGL-----PFVPVVEG 444
            |::.:|   |..||.|||  .:|  ..:..::||.....:::..    ||.|     |||.|
 Worm   262 QKSEKL---LELVGCNKT--TVD--TSMACLRLVSPEQLSLSTW----NISLTYLEFPFVIV--- 312

  Fly   445 YWNQDSQEEQFYEEPFLTQHPSDMYHSQNFNSDVAYMTGYNTHEAMLF-IRRL-----RKNPQLL 503
                 |:::.|:..  |..|.:  ....:||.||..|.|.|..|...: |.:|     :.:|..|
 Worm   313 -----SRDKHFFGH--LDAHAA--LREGDFNRDVNLMIGMNKDEGNYWNIYQLPQFFDKADPPEL 368

  Fly   504 SIIENDF----------------GRLVPQDLNVTESHDRVTREIRSFYLGSKHVGIESVDEMIAL 552
            :..|.||                .:.:..|.|.|: |.|.||    ||.|          :|..:
 Worm   369 NRTEFDFLIDRTFSIQPDIIRSAAKYIYSDPNCTD-HGRKTR----FYAG----------QMNQI 418

  Fly   553 LTDLMF----------LQGIRRTARNHAKFGNAPVYMYRFSFDGSLGLYKRMLGIPRP---GVCH 604
            :.|..|          .:.|.|...:..:.....|::|.|:...|..        |.|   |..|
 Worm   419 VGDYFFSCDSLWLADQFRSIPRVKSSSPQRKPGKVFVYHFTQSSSAN--------PWPKWTGAMH 475

  Fly   605 GDELGYLFKFGFFNLSLDPKSMEVQVKNRMVRMWTNFAKYGSP----TPDSEDPMLTTKWAPIDP 665
            |.|:.|:|... .:.|.:.|..|.....::::.|.:|||.|:|    ..:||      .|...
 Worm   476 GYEIEYVFGIP-LSYSKNYKRREQIFSRKIMQFWASFAKNGTPKLRVLKNSE------HWPEF-- 531

  Fly   666 TNVMNSLNYMDISANLAMKTNP-EPERQ---RFW----DEMY-----QHYNGAAM 707
             |..|...:|.:.:...::  | :|::|   :||    |..|     |.|:.:::
 Worm   532 -NEQNHYRWMQLRSGSNIR--PIKPKKQVECQFWRRVKDTEYTAYLTQEYSSSSL 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10175	NP_001287487.1	COesterase	157..695	CDD:278561	174/605 (29%)
ace-4	NP_496962.1	COesterase	28..562	CDD:278561	175/607 (29%)
		Aes	<120..>243	CDD:223730	60/130 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910