Protein Alignment CG10175 and Ces1e

DIOPT Version :9

• Sequence 1: NP_001287487.1
• Gene: CG10175 / 42773
• FlyBaseID: FBgn0039084
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: NP_598421.1
• Gene: Ces1e / 13897
• MGIID: 95432
• Length: 562
• Species: Mus musculus
• Alignment Length: 602
• Identity: 176/602 - (29%)
• Similarity: 265/602 - (44%)
• Gaps: 142/602 - (23%)

  Fly   158 TSLGKVRGRYQKYRSGERGGYYS----FKGMRYGAPPTGARRFRAAEPEKPWSGIRDASREGQSC 218
            |..|||.|:|....     |:..    |.|:.:..||.|:.||...:|.:|||.:::|:.....|
Mouse    29 TVQGKVLGKYISLE-----GFTQPVAVFLGVPFAKPPLGSLRFAPPQPAEPWSSVKNATSYPPMC 88

  Fly   219 ---PHKNMILD----------TFKGDEDCLFVNVFT-TQMPKDDESAEQPKLPVMVWLHGGGFSF 269
               |....|::          ..:..||||::|::| ..:.|.|      :||||||:||||...
Mouse    89 FQDPVTGQIVNDLLTNRKEKIPLQFSEDCLYLNIYTPADLTKSD------RLPVMVWIHGGGLVL 147

  Fly   270 GSGNSFLYGPDYLVA---EDIVLVTLNYRLGPLGFLTAGPD-APGNQGLKDQVLALKWVRDNIAA 330
            |..:::    |.||.   |::|:|.:.||||..||.:.|.: :.||.|..|||.||.||:||||.
Mouse   148 GGASTY----DGLVLSTHENVVVVVIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALHWVQDNIAK 208

  Fly   331 FGGDPNQVTIFGESAGASSVQLLLLSSQAKGLFHRAISQSGSALNPWSMSASSSQRAARLA---- 391
            |||||..|||||||||..||.:|:||..||.||.||||:||.||....:..::...|.::|
Mouse   209 FGGDPGSVTIFGESAGGESVSVLVLSPLAKNLFQRAISESGVALTAGLVKKNTRPLAEKIAVISG 273

  Fly   392 ------ANLGYVGANKT-EDILDFLRRVPAMKLVEAAPTTITAEDQRNNIGLPFVP-VVEGYWNQ 448
                  |.:.:....|| |::|....::...||      .:..:.::::   |||| |::|.
Mouse   274 CKNTTSAAMVHCLRQKTEEELLGTTLKLNLFKL------DLHGDSRQSH---PFVPTVLDGV--- 326

  Fly   449 DSQEEQFYEEPFLTQHPSDMYHSQNFNSDVAYMTGYNTHEAMLFIRRLRKNPQLLSIIENDFGRL 513
                       .|.:.|.::...:|||: |.|:.|.|..|                     ||.:
Mouse   327 -----------LLPKMPEEILAEKNFNT-VPYIVGINKQE---------------------FGWI 358

  Fly   514 VPQDLNVTESH---DRVTR----EIRSF---------------YLGSKHVGIESVDEMIALLTDL 556
            :|..:|...|.   |::|.    :..||               ||..|.....:.|:::.|:.|:
Mouse   359 LPTMMNYPPSDVKLDQMTAMSLLKKSSFLLNLPEDAIAVAIEKYLRDKDYTGRNKDQLLELIGDV 423

  Fly   557 MFLQGIRR--TARNHAKFGNAPVYMYRFSFDGSLGLYKRMLGIPRPGVC---HGDELGYLFKFGF 616
            :|  |:..  .:|.|...| ||.|||.|.:..|..  ..|    :|...   ||||:..:  ||.
Mouse   424 VF--GVPSVIVSRGHRDAG-APTYMYEFQYSPSFS--SEM----KPDTVVGDHGDEIYSV--FGA 477

  Fly   617 FNLSLDPKSMEVQVKNRMVRMWTNFAKYGSPTPDSEDPMLTTKWAPIDPTNVMNSLNYMDISANL 681
            ..|.......|:.:...|::.|.|||:.|:|....     ...|...|...     .|:.|.|..
Mouse   478 PILRGGTSEEEINLSKMMMKFWANFARNGNPNGQG-----LPHWPEYDQKE-----GYLQIGATT 532

  Fly   682 AMKTNPEPERQRFWDEM 698
            ......:.:...||.|:
Mouse   533 QQAQKLKEKEVAFWTEL 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10175	NP_001287487.1	COesterase	157..695	CDD:278561	173/597 (29%)
Ces1e	NP_598421.1	COesterase	25..546	CDD:278561	173/597 (29%)
		Aes	44..>242	CDD:223730	83/207 (40%)
		Prevents secretion from ER. /evidence=ECO:0000255	559..562

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.810