Protein Alignment CG10175 and ache

DIOPT Version :9

• Sequence 1: NP_001287487.1
• Gene: CG10175 / 42773
• FlyBaseID: FBgn0039084
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: NP_571921.1
• Gene: ache / 114549
• ZFINID: ZDB-GENE-010906-1
• Length: 634
• Species: Danio rerio
• Alignment Length: 676
• Identity: 188/676 - (27%)
• Similarity: 286/676 - (42%)
• Gaps: 198/676 - (29%)

  Fly   151 EREIVATTSLGKVRGRYQKYRSGERGGYYSFKGMRYGAPPTGARRFRAAEPEKPWSGIRDASREG 215
            |.::|..|.||:|:|  .:....:|....:|.|:.|..||.|.|||:.|||:|||:.:.:|....
Zfish    26 EPDLVVATRLGRVQG--TRLPVPDRSHVIAFLGIPYAEPPIGKRRFKRAEPKKPWNNVFEAKEFS 88

  Fly   216 QSCPHKNMILDT----FKG----------DEDCLFVNVFTTQMPKDDESAEQPKLPVMVWLHGGG 266
            .:|   ...:||    |.|          .||||::||:....|:..      .|.||||::|||
Zfish    89 NAC---YQFVDTSYPGFPGIEMWNPNRVMSEDCLYLNVWVPPTPRPQ------NLTVMVWIYGGG 144

  Fly   267 FSFGSGNSFLYGPDYLV-AEDIVLVTLNYRLGPLGF--LTAGPDAPGNQGLKDQVLALKWVRDNI 328
            |..||.:..:|...||. .|.:|:|::|||:|..||  |....|||||.||.||.|||:||::||
Zfish   145 FYSGSSSLDVYDGRYLAYTEKVVVVSMNYRVGAFGFLALNGSSDAPGNVGLYDQRLALQWVQENI 209

  Fly   329 AAFGGDPNQVTIFGESAGASSVQLLLLSSQAKGLFHRAISQSGSALNPWSMSA--SSSQRAARLA 391
            ..|||:|.|||||||||||:||.:.:||..::.||.|||.|||....||:...  .:.:|..:|.
Zfish   210 HFFGGNPKQVTIFGESAGAASVGMHVLSPDSRPLFTRAILQSGVPNTPWATVTFDEARRRTTKLG 274

  Fly   392 ANLGYVGANKTEDILDFLRRVPAMKLVEAAPTTITAEDQRNNIGLP--------FVPVVEGYWNQ 448
            ..:|....|.|| ::|.||.....:|:          ||...: ||        |||||:|.:..
Zfish   275 KLVGCTWGNDTE-LIDCLRNKHPQELI----------DQEWQV-LPWSSLFRFSFVPVVDGVFFP 327

  Fly   449 DSQEEQFYEEPFLTQHPSDMYHSQNFNSDVAYMTGYNTHEAMLFIRR-----LRKNPQLLSIIEN 508
            |:              |..|..|.||.. ...:.|.|..|...|:..     .:.|..|:|  ..
Zfish   328 DT--------------PDAMISSGNFKY-TQILLGVNQDEGSYFLLYGAPGFSKDNESLIS--RE 375

  Fly   509 DFGRLVPQDLNVTESHDRVTREIRSFYLGSKH---VGIESV-----------------DEMIALL 553
            ||                    :.|..:|..|   :|:|:|                 |.|..::
Zfish   376 DF--------------------LESVKMGVPHANDIGLEAVILQYTDWMDENNGQKNRDAMDDIV 420

  Fly   554 TDLMFLQGIRRTARNHAKF---------------------------GNA--PVYMYRFSFDGSLG 589
            .|...:..::..|:::|::                           ||:  .||:|.|....|..
Zfish   421 GDQNVICPLQHFAKSYAQYAALHAQSSAAAPGTLGWGNSGPTGYNSGNSHGAVYLYLFDHRASNL 485

  Fly   590 LYKRMLGIPRPGVCHGDELGYLFKFGFFNLSLDPK----SMEVQVKNRMVRMWTNFAKYGSPTPD 650
            .:...:     ||.||.|:.::     |.|.|:.:    :.|.::..|::|.|.|||:.|:|..:
Zfish   486 AWPEWM-----GVIHGYEIEFV-----FGLPLEKRLNYTAEEEKLSRRIMRYWANFARTGNPNVN 540

  Fly   651 SEDPMLTTKWAP-------------IDPTNVMNSL-------------NYMDISANLAMKTNPEP 689
            ::..|.:.:..|             .:|..|...|             ..::|:.|:     .:.
Zfish   541 TDGTMDSRRRWPQFSANEQKHVGLNTEPMKVHKGLRTQFCALWNRFLPRLLNITDNI-----DDV 600

  Fly   690 ERQ------------RFWDEMYQHYN 703
            |||            ..|...:.||:
Zfish   601 ERQWKVEFHRWSSYMMHWKSQFDHYS 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10175	NP_001287487.1	COesterase	157..695	CDD:278561	183/660 (28%)
ache	NP_571921.1	COesterase	23..583	CDD:278561	180/626 (29%)
		AChE_tetra	598..631	CDD:285837	6/29 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.810