Protein Alignment CG10175 and Ache

DIOPT Version :10

• Sequence 1: NP_001287487.1
• Gene: CG10175 / 42773
• FlyBaseID: FBgn0039084
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: XP_036020624.1
• Gene: Ache / 11423
• MGIID: 87876
• Length: 616
• Species: Mus musculus
• Alignment Length: 599
• Identity: 184/599 - (30%)
• Similarity: 279/599 - (46%)
• Gaps: 119/599 - (19%)

  Fly   149 RKEREIVATTSLGKVRGRYQKYRSGERGGYYS-FKGMRYGAPPTGARRFRAAEPEKPWSGIRDAS 212
            |::.:::.....|::||    .|....||..| |.|:.:..||.|:|||...||::||||:.||:
Mouse    34 REDPQLLVRVRGGQLRG----IRLKAPGGPVSAFLGIPFAEPPVGSRRFMPPEPKRPWSGVLDAT 94

  Fly   213 REGQSC-PHKNMILDTFKG----------DEDCLFVNVFTTQMPKDDESAEQPKLPVMVWLHGGG 266
            .....| .:.:.:...|:|          .||||::||: |..|:.....     ||::|::|||
Mouse    95 TFQNVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVW-TPYPRPASPT-----PVLIWIYGGG 153

  Fly   267 FSFGSGNSFLYGPDYLV-AEDIVLVTLNYRLGPLGFLT--AGPDAPGNQGLKDQVLALKWVRDNI 328
            |..|:.:..:|...:|. .|..|||::|||:|..|||.  ...:||||.||.||.|||:||::||
Mouse   154 FYSGAASLDVYDGRFLAQVEGAVLVSMNYRVGTFGFLALPGSREAPGNVGLLDQRLALQWVQENI 218

  Fly   329 AAFGGDPNQVTIFGESAGASSVQLLLLSSQAKGLFHRAISQSGSALNPW-SMSASSSQRAARLAA 392
            |||||||..||:|||||||:||.:.:||..::.|||||:.|||:...|| ::||..::|.|.|.|
Mouse   219 AAFGGDPMSVTLFGESAGAASVGMHILSLPSRSLFHRAVLQSGTPNGPWATVSAGEARRRATLLA 283

  Fly   393 NL-----GYVGANKTEDILDFLRRVPAMKLVE----AAPTTITAEDQRNNIGLPFVPVVEGYWNQ 448
            .|     |..|.|.|| ::..||..||..||:    ..|       |.:.....|||||:|
Mouse   284 RLVGCPPGGAGGNDTE-LIACLRTRPAQDLVDHEWHVLP-------QESIFRFSFVPVVDG---- 336

  Fly   449 DSQEEQFYEEPFLTQHPSDMYHSQNFNSDVAYMTGYNTHEAMLFI-----RRLRKNPQLLSIIEN 508
                      .||:..|..:.::.:| .|:..:.|....|...|:     ...:.|..|:|..:
Mouse   337 ----------DFLSDTPEALINTGDF-QDLQVLVGVVKDEGSYFLVYGVPGFSKDNESLISRAQ- 389

  Fly   509 DFGRLVPQDLNVTESHDRVTREIRSFYLGSKH--------------VGIESVDEMIALLTDLMFL 559
               .|....:.|.::.|.....:...|....|              ||..:|...:|.|...:..
Mouse   390 ---FLAGVRIGVPQASDLAAEAVVLHYTDWLHPEDPTHLRDAMSAVVGDHNVVCPVAQLAGRLAA 451

  Fly   560 QGIRRTARNHAKFGNAPVYMYRFSFDGSLGLYKRMLGIPRPGVCHGDELGYLFKFGFFNLSLDPK 624
            ||.|             ||.|.|....|...:...:|:|     ||.|:.::     |.|.|||.
Mouse   452 QGAR-------------VYAYIFEHRASTLTWPLWMGVP-----HGYEIEFI-----FGLPLDPS 493

  Fly   625 ---SMEVQV-KNRMVRMWTNFAKYGSPTP--DSEDPMLTTKWAPIDPTNVMNSLNYMDISAN-LA 682
               :.|.:: ..|:::.|||||:.|.|..  ||:.|    :|.|....    :..|:.::.. |.
Mouse   494 LNYTTEERIFAQRLMKYWTNFARTGDPNDPRDSKSP----QWPPYTTA----AQQYVSLNLKPLE 550

  Fly   683 MKTNPEPERQRFWD 696
            ::.....:...||:
Mouse   551 VRRGLRAQTCAFWN 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10175	NP_001287487.1	COesterase	155..695	CDD:395084	181/590 (31%)
Ache	XP_036020624.1	COesterase	37..563	CDD:395084	181/593 (31%)