Protein Alignment CG10175 and Ces1d

DIOPT Version :10

• Sequence 1: NP_001287487.1
• Gene: CG10175 / 42773
• FlyBaseID: FBgn0039084
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: NP_444430.2
• Gene: Ces1d / 104158
• MGIID: 2148202
• Length: 565
• Species: Mus musculus
• Alignment Length: 622
• Identity: 182/622 - (29%)
• Similarity: 266/622 - (42%)
• Gaps: 118/622 - (18%)

  Fly   112 STTETTAWKTLTSHPNSLVQLLPSRAMRVVQEVVRSLRKEREIVATTSLGKVRGRYQKYRSGERG 176
            |....|||...:|.|                            |..|..|||.|:|....
Mouse    10 SLAACTAWGYPSSPP----------------------------VVNTVKGKVLGKYVNLE----- 41

  Fly   177 GYYS----FKGMRYGAPPTGARRFRAAEPEKPWSGIRDASREGQSCPHK----NMILDTFKG--- 230
            |:..    |.|:.:..||.|:.||...:|.:|||.:::.:.....|...    .::.:.|..
Mouse    42 GFTQPVAVFLGVPFAKPPLGSLRFAPPQPAEPWSFVKNTTSYPPMCSQDAVGGQVLSELFTNRKE 106

  Fly   231 ------DEDCLFVNVFTTQMPKDDESAEQPKLPVMVWLHGGGFSFGSGNSFLYGPDYLVA---ED 286
                  .||||::|::|   |.|  ..:..:||||||:||||...|..:::    |.|..   |:
Mouse   107 NIPLQFSEDCLYLNIYT---PAD--LTKNSRLPVMVWIHGGGLVVGGASTY----DGLALSAHEN 162

  Fly   287 IVLVTLNYRLGPLGFLTAGPD-APGNQGLKDQVLALKWVRDNIAAFGGDPNQVTIFGESAGASSV 350
            :|:||:.||||..||.:.|.: :.||.|..|||.||:||:||||.|||:|..|||||||||..||
Mouse   163 VVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIANFGGNPGSVTIFGESAGGFSV 227

  Fly   351 QLLLLSSQAKGLFHRAISQSGSALNPWSMSASSSQRAARLAANLGYVGANKTEDILDFLRRVPAM 415
            .:|:||..||.|||||||:||.:|.. ::..:..:..|.|.|.|.......:..::..||:....
Mouse   228 SVLVLSPLAKNLFHRAISESGVSLTA-ALITTDVKPIAGLVATLSGCKTTTSAVMVHCLRQKTED 291

  Fly   416 KLVEAA-PTTITAEDQRNN--IGLPFVP-VVEGYWNQDSQEEQFYEEPFLTQHPSDMYHSQNFNS 476
            :|:|.: ...:...|...|  ...||:| |::|.....:.||...|:.|.|.......:.|.|..
Mouse   292 ELLETSLKLNLFKLDLLGNPKESYPFLPTVIDGVVLPKAPEEILAEKSFSTVPYIVGINKQEFGW 356

  Fly   477 DVAYMTGYNTHEAMLFIRR----LRKNPQLLSIIENDFGRLVPQDLNVTESHDRVTREIRSFYLG 537
            .:..:.||...|..|..:.    |.|:...|.|.||    ::|.   |.|.           |||
Mouse   357 IIPTLMGYPLAEGKLDQKTANSLLWKSYPTLKISEN----MIPV---VAEK-----------YLG 403

  Fly   538 SKHVGIESVDEMIALLTDLMFLQGIRR--TARNHAKFGNAPVYMYRFSFDGSLGLYKRMLGIPRP 600
            ......:..|....|:.|::|  |:..  .:|:|...| |..|||.|.:..|      .:...||
Mouse   404 GTDDLTKKKDLFQDLMADVVF--GVPSVIVSRSHRDAG-ASTYMYEFEYRPS------FVSAMRP 459

  Fly   601 GVC---HGDELGYLFKFGFFNLSLDPKSMEVQVKNRMV-RMWTNFAKYGSPTPDSEDPMLTTKWA 661
            ...   ||||:..:|...|..   |..|.|....::|| :.|.|||:.|:|....     ...|.
Mouse   460 KAVIGDHGDEIFSVFGSPFLK---DGASEEETNLSKMVMKFWANFARNGNPNGGG-----LPHWP 516

  Fly   662 PIDPTNVMNSLNYMDISANLAMKTNPEPERQRFWDEM 698
            ..|...     .|:.|.|:.......:.:...||.|:
Mouse   517 EYDQKE-----GYLKIGASTQAAQRLKDKEVSFWAEL 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10175	NP_001287487.1	COesterase	155..695	CDD:395084	173/574 (30%)
Ces1d	NP_444430.2	COesterase	22..545	CDD:395084	175/605 (29%)
		Prevents secretion from ER. /evidence=ECO:0000255	562..565