DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10175 and LOC100334697

DIOPT Version :9

Sequence 1:	NP_001287487.1	Gene:	CG10175 / 42773	FlyBaseID:	FBgn0039084	Length:	707	Species:	Drosophila melanogaster
Sequence 2:	XP_002661384.2	Gene:	LOC100334697 / 100334697	-ID:	-	Length:	576	Species:	Danio rerio

Alignment Length:	564	Identity:	163/564 - (28%)
Similarity:	249/564 - (44%)	Gaps:	103/564 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   179 YSFKGMRYGAPPTGARRFRAAEPEKPWSGIRDASREGQSCPHK--NMILDTF--KGDEDCLFVNV 239
            |.|.|:.:..||.|..|::|..|..||.|:.|||....:|...  ..|.|..  |..||||::||
Zfish    68 YVFYGIPFADPPVGTSRWKAPRPVTPWKGVYDASFPRAACMQACIGPIADDCPKKVSEDCLYLNV 132

  Fly   240 FTTQMPKDDESAE---QPKLPVMVWLHGGGFSFGSGNSFLYGPDYLV-AEDIVLVTLNYRLGPLG 300
            |   :|...:.|.   || ||||:|:|||.|..||.:..||...::. ....|:|::.||||..|
Zfish   133 F---VPLSVDLATPLLQP-LPVMLWIHGGDFIAGSASKPLYDGRFISNYTQTVIVSIAYRLGAFG 193

  Fly   301 FLTAGPD----APGNQGLKDQVLALKWVRDNIAAFGGDPNQVTIFGESAGASSVQLLLLSSQAKG 361
            ||.:|.|    |.||.|:.||..||.||:.|||||||||::||||||||||.||.|.|:...:|.
Zfish   194 FLVSGKDPKSTAVGNYGILDQQAALIWVQQNIAAFGGDPSRVTIFGESAGAQSVSLHLMIQSSKP 258

  Fly   362 LFHRAISQSGSALNPWSMSASSSQRAARLAANLGYVGANKTEDILDFLRRVPAMKLVEAAPTTIT 426
            ||.:|:.||    .|:|:...:.:.:.:|..:.........||          ||.::    :::
Zfish   259 LFKQAVFQS----LPFSIPLKTRRESLKLGKHFAKAANCSLED----------MKCLQ----SLS 305

  Fly   427 AED-------QRNNIGLP--FVPVVEGYWNQDSQEEQFYEEPFLTQHPSDMYHSQNFNSDVAYMT 482
            |||       ..:.:..|  |:.|.| .|.      .|.:...:.:.....:...::..:...:.
Zfish   306 AEDVLHAQIKTSSKLVNPFRFLEVFE-IWG------PFIDGELIKEQAVSAFQKGHWQKEKPVLL 363

  Fly   483 GYNTHEAMLFIRRLRKNPQLLSIIENDFGRLVPQDLNVTESHD-RVTREIRSFYLGSKHVGIESV 546
            |..:.|.::|:..:.|.|  :|.:|     .......:.:.|. ::.|:....|..:     :..
Zfish   364 GTTSEEGVIFVYGVFKKP--VSAVE-----CTIYTTAIFKQHAIKILRKYLPLYSDA-----DRR 416

  Fly   547 DEMIALLTDLMFLQGIRRTARNHAKFGNAPVYMYRFS--------FDGSLGLYKRMLGIPRPGVC 603
            |.:..::||.:|....||:|| .|....:..:||.|.        :.|....|:|        ||
Zfish   417 DMLAQIVTDYIFWCPSRRSAR-AAVLSGSSAWMYVFDQVSSDPRVWSGVSSCYQR--------VC 472

  Fly   604 HGDELGYLF-KFGFFNLSLDPKSMEVQVKNRMVRMWTNFAKYGSPTPDSEDP-----MLTTKWAP 662
            ||.||.::| .....|.|:.|  .|..:.||::..|..||..|:||.::..|     ....:..|
Zfish   473 HGAELPFVFDSASVANFSMTP--AEKLLSNRVLCYWGGFAHTGNPTGETRRPSDISGFCRQQRPP 535

  Fly   663 IDPTNVMNSLNYMDISANLAMKTNPEPERQR--------FWDEM 698
            ..|:...|       ...:.|.....|..|.        |||.:
Zfish   536 SWPSYTAN-------RGWMIMNLTAHPHSQAGYGEDICDFWDTL 572

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10175	NP_001287487.1	COesterase	157..695	CDD:278561	160/559 (29%)
LOC100334697	XP_002661384.2	COesterase	44..569	CDD:278561	160/559 (29%)
LOC100334697	XP_002661384.2	Aes	<138..>245	CDD:223730	55/107 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910