Protein Alignment CG10175 and nlgn2

DIOPT Version :10

• Sequence 1: NP_001287487.1
• Gene: CG10175 / 42773
• FlyBaseID: FBgn0039084
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: XP_031755501.1
• Gene: nlgn2 / 100329187
• XenbaseID: XB-GENE-6034906
• Length: 810
• Species: Xenopus tropicalis
• Alignment Length: 612
• Identity: 183/612 - (29%)
• Similarity: 271/612 - (44%)
• Gaps: 110/612 - (17%)

  Fly   155 VATTSLGKVRGRYQKYRSGERGGYYSFKGMRYGAPPTGARRFRAAEPEKPWSGIRDASREGQSCP 219
            |..|:.||:||..:...:...|....:.|:.|..||.|.|||:|.|....|:.:|:|:.....||
 Frog    30 VVNTNYGKLRGVKKDLNNEILGPVVQYLGIPYATPPIGERRFQAPEAPASWTEVRNATTFAPVCP 94

  Fly   220 H----------------KNMILDTFKG-----DEDCLFVNVFT----------------TQMPKD 247
            .                :||  |...|     .||||::|::.                .|...|
 Frog    95 QNLHGMLPGIMLPLWFTENM--DVVAGYVQNQSEDCLYLNIYVPLEDGPISKSREDPRKAQHTPD 157

  Fly   248 DESAEQPKLPVMVWLHGGGFSFGSGNSF------LYGPDYLVAEDIVLVTLNYRLGPLGFLTAGP 306
            ::..:..|.|||:::|||.:..|:||.|      .||       ::::||||||||.|||::.|.
 Frog   158 EDIRDSGKKPVMMFIHGGSYMEGTGNMFDGSVLAAYG-------NVIVVTLNYRLGILGFMSTGD 215

  Fly   307 D-APGNQGLKDQVLALKWVRDNIAAFGGDPNQVTIFGESAGASSVQLLLLSSQAKGLFHRAISQS 370
            . |.||.||.||:.||:|:.:||..|||||.::||||..||||.|.||:||..::|||.:||:||
 Frog   216 QAAKGNYGLLDQIQALRWLEENIGHFGGDPERITIFGSGAGASCVSLLILSHHSEGLFQKAIAQS 280

  Fly   371 GSALNPWSMSASSSQRAARLAANLGYVGANKTEDILDFLRRVPAMKLVEAAPTTITAEDQRNNIG 435
            |:|::.||::....:....|||.:|......:|.:: .|||.|...||:       .:.|.....
 Frog   281 GTAISSWSVNYEPLKYTRLLAAKVGCDYQENSEMVM-CLRRKPYRDLVD-------QDIQPARYH 337

  Fly   436 LPFVPVVEGYWNQDSQEEQFYEEPFLTQHPSDMYHSQNFNSDVAYMTGYNTHEAMLFIRRLRKNP 500
            :.|.|||:|....|..|....:..||             |.|:  :.|.|..|.:.|:....::.
 Frog   338 IAFGPVVDGDVVPDDPEILMEQGEFL-------------NYDI--LMGVNQGEGLKFVEDTLESE 387

  Fly   501 QLLSIIENDF--GRLVPQDLNVTESHDRVTREIRSFYL--GSKHVGIESVDEMIALLTDLMFLQG 561
            ..:|....||  ...|.......|..|.:...|:..|.  ..:..|......::||.||..::..
 Frog   388 DGISNSYFDFTVSNFVDNLYGFAEGKDVLRETIKFMYTDWADRDNGDMRRKTLLALFTDHQWVAP 452

  Fly   562 IRRTARNHAKFGNAPVYMYRFSFDGSLGLYKRMLGIPRP---GVCHGDELGYLFKFGFFNLS-LD 622
            ...||:.||:: .:|||.|.|        |.|.....||   ...||||:.|:|.......: |.
 Frog   453 AIATAKFHAEY-ESPVYFYAF--------YHRCQAEGRPEWGEAAHGDEVPYVFGVPMVGATDLF 508

  Fly   623 P---KSMEVQVKNRMVRMWTNFAKYGSPT-PDSED-PMLTTK--------WAPIDPTNVMNSLNY 674
            |   ...:|.:...::..||||||.|.|. |..:| ..:.||        |...:|    ....|
 Frog   509 PCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVVWTKFNP----KEKQY 569

  Fly   675 MDISANLAMKTNPEPERQRFWDEMYQH 701
            :.|.....:|.|....:..||.|:..|
 Frog   570 LHIGLKPRVKDNYRANKVAFWLELVPH 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10175	NP_001287487.1	COesterase	155..695	CDD:395084	179/604 (30%)
nlgn2	XP_031755501.1	COesterase	29..590	CDD:395084	179/604 (30%)