Protein Alignment CG10175 and Ces1f

DIOPT Version :10

• Sequence 1: NP_001287487.1
• Gene: CG10175 / 42773
• FlyBaseID: FBgn0039084
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: NP_001096829.2
• Gene: Ces1f / 100125372
• RGDID: 1642419
• Length: 561
• Species: Rattus norvegicus
• Alignment Length: 609
• Identity: 170/609 - (27%)
• Similarity: 258/609 - (42%)
• Gaps: 134/609 - (22%)

  Fly   155 VATTSLGKVRGRYQKYRSGERGGYYSFKGMRYGAPPTGARRFRAAEPEKPWSGIRDASREGQSCP 219
            |..|:.|||.|:|... .|.......|.|:.:..||.|:.||...:|.:|||.:::.:.....|.
  Rat    25 VVDTTKGKVLGKYVSL-EGVTQSVAVFLGVPFAKPPLGSLRFAPPQPAEPWSFVKNTTTYPPMCS 88

  Fly   220 HKNMILDTFKG------------------DEDCLFVNVFTTQMPKDDESAEQPKLPVMVWLHGGG 266
            .     |..||                  .||||::|::|   |.|  ..:..:||||||:||||
  Rat    89 Q-----DAAKGQRMNDLLTNRKEKIHLEFSEDCLYLNIYT---PAD--FTKNSRLPVMVWIHGGG 143

  Fly   267 FSFGSGNSFLYGPDYLVA-EDIVLVTLNYRLGPLGFLTAGPD-APGNQGLKDQVLALKWVRDNIA 329
            .:.|..::  |....|.| |::|:|.:.||||..||.:.|.: :.||.|..|||.||.||:||||
  Rat   144 MTLGGAST--YDGRVLSAYENVVVVAIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALHWVQDNIA 206

  Fly   330 AFGGDPNQVTIFGESAGASSVQLLLLSSQAKGLFHRAISQSGSALNPWSMSASSSQRAARLAANL 394
            .|||||..|||||||||..||.:|:||...|.|||||||:||....|..::......|.::|...
  Rat   207 NFGGDPGSVTIFGESAGGFSVSVLVLSPLTKNLFHRAISESGVVFLPGLLTKDVRPAAKQIADMA 271

  Fly   395 G----------YVGANKT-EDILDFLRRVPAMKLVEAAPTTITAEDQRNNIGLPFVPVVEGYWNQ 448
            |          :....|| |::|:.::::..:||          ..||:|
  Rat   272 GCETTTSAIIVHCLRQKTEEELLEIMKKMNLIKL----------SSQRDN--------------- 311

  Fly   449 DSQEEQFY------EEPFLTQHPSDMYHSQNFNSDVAYMTGYNTHEAMLFIRRLRKNPQLLSIIE 507
               :|.::      :...|.:.|.::...:|||: |.|:.|.|..|....:      |.::..:.
  Rat   312 ---KESYHFLSTVVDNVVLPKDPKEILAEKNFNT-VPYIVGINKQECGWLL------PTMMGFVP 366

  Fly   508 ND--------------FGRL--VPQDLNVTESHDRVTREIRSFYLGSKHVGIESVDEMIALLTDL 556
            .|              |..|  :|:|:        :...|..:..||.. .|:..|.::|.:.|:
  Rat   367 ADVELDKKMAITLLEKFASLYGIPEDI--------IPVAIEKYRKGSDD-SIKIRDGILAFIGDV 422

  Fly   557 MFLQGIRRTARNHAKFGNAPVYMYRFSFDGSLGLYKRMLGIPRPGVCHGDELGYLFK-FGFFNLS 620
            .|.......:|:|...| ||.|||.:.:      |.......||....||....|:. ||...|.
  Rat   423 SFSIPSVMVSRDHRDAG-APTYMYEYQY------YPSFSSPQRPKHVVGDHADDLYSVFGAPILR 480

  Fly   621 LDPKSMEVQVKNRMVRMWTNFAKYGSPTPDSEDPMLTTKWAPIDPTNVMNSLNYMDISANLAMKT 685
            ......|:::...:::.|.|||:.|:|....     ...|...|...     .|:.|.|......
  Rat   481 DGASEEEIKLSKMVMKFWANFARNGNPNGRG-----LPHWPQYDQKE-----EYLQIGATTQQSQ 535

  Fly   686 NPEPERQRFWDEM------YQHYN 703
            ..:.|...||.::      ..|:|
  Rat   536 RLKAEEVAFWTQLLAKRQPQPHHN 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10175	NP_001287487.1	COesterase	155..695	CDD:395084	166/593 (28%)
Ces1f	NP_001096829.2	COesterase	22..545	CDD:395084	166/593 (28%)
		Prevents secretion from ER. /evidence=ECO:0000255|PROSITE-ProRule:PRU10138	558..561		1/2 (50%)