Protein Alignment CG10175 and nlgn2b

DIOPT Version :9

• Sequence 1: NP_001287487.1
• Gene: CG10175 / 42773
• FlyBaseID: FBgn0039084
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: NP_001159808.1
• Gene: nlgn2b / 100002407
• ZFINID: ZDB-GENE-090918-3
• Length: 860
• Species: Danio rerio
• Alignment Length: 665
• Identity: 191/665 - (28%)
• Similarity: 294/665 - (44%)
• Gaps: 120/665 - (18%)

  Fly   109 MGSSTTETTAWKTLTSHP-----NSLVQLLPSRAMRVVQEVVR--SLRKEREIVATTSLGKVRGR 166
            |.|.....:..:|:.|.|     ..||.|| ..|:|:.....:  .|...:..:.||..||:||.
Zfish     1 MSSVDVARSRRETVRSCPRRISDTCLVWLL-GLALRLALSSCQRADLTTAKHPMVTTGYGKLRGV 64

  Fly   167 YQKYRSGERGGYYSFKGMRYGAPPTGARRFRAAEPEKPWSGIRDASREGQSCPHK------NMIL 225
            .::..:...|....:.|:.|..||.|.|||:..|....|..||:|::....||..      .::|
Zfish    65 RKELNNEILGPVEQYLGVPYATPPVGERRFQPPEAPGSWQEIRNATQFAPVCPQNIHGVLPEIML 129

  Fly   226 DTFKGD-------------EDCLFVNVF---------------TTQMPKDDESAEQPKLPVMVWL 262
            ..:..|             ||||::||:               :...|:|::..::.|.|||:::
Zfish   130 PVWFTDNLDAAAAYVQNQSEDCLYLNVYVPTEDGPLTKKHDESSMNRPRDEDIRDRRKKPVMLFI 194

  Fly   263 HGGGFSFGSGNSF------LYGPDYLVAEDIVLVTLNYRLGPLGFLTAG-PDAPGNQGLKDQVLA 320
            |||.|..|:||.|      .||       ::::||:|||||.||||::| ..|.||.||.||:.|
Zfish   195 HGGSFMEGTGNMFDASVLAAYG-------NVIVVTMNYRLGVLGFLSSGDQSAKGNYGLLDQIQA 252

  Fly   321 LKWVRDNIAAFGGDPNQVTIFGESAGASSVQLLLLSSQAKGLFHRAISQSGSALNPWSMSASSSQ 385
            |:|:.:||..|||||.::||||..||||.|.||:||..::|||.|||:|||||::.||::.....
Zfish   253 LRWLNENIGHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFQRAIAQSGSAISSWSVNYRPLM 317

  Fly   386 RAARLAANLGYVGANKTEDILDFLRRVPAMKLVEAAPTTITAEDQRNNIGLPFVPVVEGYWNQDS 450
            ....||..:| ...:.|.|::|.|||....:||:       .:.|.....:.|.|||:|....|.
Zfish   318 YTKILAKKVG-CSYSDTADLVDCLRRKSYRELVD-------QDVQPARYHIAFGPVVDGDVVPDD 374

  Fly   451 QEEQFYEEPFLTQHPSDMYHSQNFNSDVAYMTGYNTHEAMLFIRRLRKNPQLLSIIENDF--GRL 513
            .|....:..||             |.|:  :.|.|..|.:.|:.. .:..:.:|....|:  ...
Zfish   375 PEILMQQGEFL-------------NYDI--LLGVNQGEGLKFVDD-NEGEEGISAASFDYTISNF 423

  Fly   514 VPQDLNVTESHDRVTREIRSFYL--GSKHVGIESVDEMIALLTDLMFLQGIRRTARNHAKFGNAP 576
            |.......|..|.:...|:..|.  ..:..|......::||.||..::.....||:.||:| .:|
Zfish   424 VDNLYGYPEGKDILRETIKFMYTDWADRDNGDMRRKTLLALFTDHQWVAPAVATAKLHAEF-QSP 487

  Fly   577 VYMYRFSFDGSLGLYKRMLGIPRP---GVCHGDELGYLFKFGFFNLS-LDP---KSMEVQVKNRM 634
            ||.|.|        :.......||   ...||||:.|:|.......: |.|   ...::.:...:
Zfish   488 VYFYTF--------HHHCQTEARPEWADAAHGDEIPYVFGVPMVGATELFPCNFSKNDIMLSAVV 544

  Fly   635 VRMWTNFAKYGSPT-------------PDSEDPMLTTKWAPIDPTNVMNSLNYMDISANLAMKTN 686
            :..||||||.|.|.             |:..:.::.||::..|.       .|:.|.....::.|
Zfish   545 MTYWTNFAKTGDPNIPVPQDTKFIHTKPNRFEEVIWTKFSSKDK-------QYLHIGLKPRIRDN 602

  Fly   687 PEPERQRFWDEMYQH 701
            ....:..||.|:..|
Zfish   603 YRANKVAFWLELVPH 617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10175	NP_001287487.1	COesterase	157..695	CDD:278561	175/602 (29%)
nlgn2b	NP_001159808.1	COesterase	47..611	CDD:278561	175/610 (29%)
		Aes	<181..>279	CDD:223730	48/104 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810