DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10177 and STK17A

DIOPT Version :9

Sequence 1:NP_651150.1 Gene:CG10177 / 42772 FlyBaseID:FBgn0039083 Length:411 Species:Drosophila melanogaster
Sequence 2:NP_004751.2 Gene:STK17A / 9263 HGNCID:11395 Length:414 Species:Homo sapiens


Alignment Length:259 Identity:74/259 - (28%)
Similarity:115/259 - (44%) Gaps:20/259 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly   165 RGQTRANRTKC---------TVKMVNKQTQSND-RGDTYMEAEVLRQLQSHPNIIELMYTVEDER 219
            ||:....| ||         ..|.:.|:.:..| |.:...|..||...|.:|.:|.|....|...
Human    69 RGKFAVVR-KCIKKDSGKEFAAKFMRKRRKGQDCRMEIIHEIAVLELAQDNPWVINLHEVYETAS 132

  Fly   220 YMYTVLEHL---DCNMQKVIQKRGILSEADARSVMRCTVSALAHMHQLQVIHRDIKPENLLVCSS 281
            .|..|||:.   :...|.|..:.....|.|.:.:||..:..:..:|...|:|.|:||:|:|:.|.
Human   133 EMILVLEYAAGGEIFDQCVADREEAFKEKDVQRLMRQILEGVHFLHTRDVVHLDLKPQNILLTSE 197

  Fly   282 SGKWNFKMVKVANFDLATYYRGS-KLYVRCGTPCYMAPEMIAMSGYDYQVDSWSLGVTLFYMLCG 345
            |...:   :|:.:|.|:...:.| :|....|||.|:|||:::........|.||:||..:.||.|
Human   198 SPLGD---IKIVDFGLSRILKNSEELREIMGTPEYVAPEILSYDPISMATDMWSIGVLTYVMLTG 259

  Fly   346 KMPFASACKNSKEIYAAIMSGGPTYPKDMESVMSPEATQLIDGLLVSDPSYRVPIAELDKFQFL 409
            ..||..  .:.:|.:..|.....:|.::...|:|..|...|..|||..|..|....|..|..:|
Human   260 ISPFLG--NDKQETFLNISQMNLSYSEEEFDVLSESAVDFIRTLLVKKPEDRATAEECLKHPWL 321

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10177NP_651150.1 DCX 18..108 CDD:214711
S_TKc 164..409 CDD:214567 73/257 (28%)
PKc_like 164..403 CDD:304357 71/251 (28%)
STK17ANP_004751.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..40
STKc_DRAK1 51..321 CDD:271099 73/257 (28%)
S_TKc 64..321 CDD:214567 73/257 (28%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 342..363
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0032
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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