DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10177 and SKS1

DIOPT Version :9

Sequence 1:	NP_651150.1	Gene:	CG10177 / 42772	FlyBaseID:	FBgn0039083	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	NP_015299.1	Gene:	SKS1 / 856081	SGDID:	S000005947	Length:	502	Species:	Saccharomyces cerevisiae

Alignment Length:	254	Identity:	62/254 - (24%)
Similarity:	102/254 - (40%)	Gaps:	58/254 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   193 YMEAEVLRQLQSHPNIIELMYTVEDERYMYTVLEHLDCNM------QKVIQKRGILSEADARSVM 251
            |.|.....::|||.||:::...:|.....:.|:::.|.::      .|.....|||    .:.|.
Yeast   107 YREIAFQLRVQSHGNIVKIHQVLESSIATFIVMDYYDRDLFTSIVDDKHFVNHGIL----IKKVF 167

  Fly   252 RCTVSALAHMHQLQVIHRDIKPENLLVCSSSGKWNFKMVKVANFDLATYYRGSKLYVRCGTPCYM 316
            ....|||.|.|:|.:.|.||||||:|:..:...:      :.:|.|:|..:.....|..|:..||
Yeast   168 LQLCSALDHCHRLGIYHCDIKPENVLLDRNDNAY------LCDFGLSTKSKYLAPNVCVGSSYYM 226

  Fly   317 APEMI------AMSGYDYQV----------DSWSLGVTLFYMLCGKMPFASACKN---------- 355
            |||.|      ..:|.....          |.||||:.|..:.|.:.|:..|.:.
Yeast   227 APERILYCLNTTTNGIHVDECCSSLPTDTGDIWSLGIILINLTCIRNPWLKAHQKEDNTFQHFAN 291

  Fly   356 -----------SKEIYAA---IMSGGPTYPKDMESVMSPEATQLIDGLLVSDPSYRVPI 400
                       |.|::..   |:...|....||:::||..::  :.......|..:|||
Yeast   292 DNNVLKKILPISDELFTVLTKILQLNPYTRIDMKTLMSEVSS--LTSFTREGPLSQVPI 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10177	NP_651150.1	DCX	18..108	CDD:214711
		S_TKc	164..409	CDD:214567	62/254 (24%)
		PKc_like	164..403	CDD:304357	62/254 (24%)
SKS1	NP_015299.1	PKc_like	9..331	CDD:419665	58/233 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345250
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930