DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10177 and NPR1

DIOPT Version :9

Sequence 1:	NP_651150.1	Gene:	CG10177 / 42772	FlyBaseID:	FBgn0039083	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	NP_014216.1	Gene:	NPR1 / 855538	SGDID:	S000005127	Length:	790	Species:	Saccharomyces cerevisiae

Alignment Length:	210	Identity:	49/210 - (23%)
Similarity:	97/210 - (46%)	Gaps:	25/210 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   204 SHPNIIELMYTVEDERYMYTVLEHLDCNMQKVIQKRGILSEADARSVMRCTVSALAHMHQLQVIH 268
            :||||||.:..|.:...:..|:|:.:.::..::.... :|..:.....:..::.:.::|.:.:.|
Yeast   496 NHPNIIETIEIVYENDRILQVMEYCEYDLFAIVMSNK-MSYEEICCCFKQILTGVQYLHSIGLAH 559

  Fly   269 RDIKPENLLVCSSSGKWNFKMVKVANFDLATY--YRGSKLYVRC----GTPCYMAPEMIAMSGYD 327
            ||:|.:|.:: :..|     :||:.:|..|..  |..||..|..    |:..|:|||:...:.||
Yeast   560 RDLKLDNCVI-NEKG-----IVKLIDFGAAVVFSYPFSKNLVEASGIVGSDPYLAPEVCIFAKYD 618

  Fly   328 YQ-VDSWSLGVTLFYMLCGKMPF--ASACKNSKEIY---------AAIMSGGPTYPKDMESVMSP 380
            .: ||.||..:....|:..|.|:  .....||.:::         :::::..|..|...||..:.
Yeast   619 PRPVDIWSSAIIFACMILKKFPWKIPKLRDNSFKLFCSGRDCDSLSSLVTRTPDPPSYDESHSTE 683

  Fly   381 EATQLIDGLLVSDPS 395
            :.........||||:
Yeast   684 KKKPESSSNNVSDPN 698

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10177	NP_651150.1	DCX	18..108	CDD:214711
		S_TKc	164..409	CDD:214567	49/210 (23%)
		PKc_like	164..403	CDD:304357	49/210 (23%)
NPR1	NP_014216.1	PKc_like	451..742	CDD:419665	49/210 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345258
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930