Protein Alignment CG10177 and MEK1

DIOPT Version :10

• Sequence 1: NP_651150.1
• Gene: CG10177 / 42772
• FlyBaseID: FBgn0039083
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_014996.3
• Gene: MEK1 / 854533
• SGDID: S000005878
• Length: 497
• Species: Saccharomyces cerevisiae
• Alignment Length: 378
• Identity: 84/378 - (22%)
• Similarity: 143/378 - (37%)
• Gaps: 103/378 - (27%)

  Fly    77 DGSHLTSLSCFRETDIVICCC--------------KNEEIICVKYSINKDFQRMVDSCKRWGQHH 127
            :|::|..|...|:...::..|              |...::   :.||.|.|..:|      ...
Yeast    93 NGTYLNGLLLKRDKTYLLKHCDVIELSQGSEENDIKKTRLV---FMINDDLQSSLD------PKL 148

  Fly   128 LDS-GTLESMKSHDLPEAIQLYIETIEPVEHNT--RTLIYRGQTRANRTKC------TVKMVNKQ 183
            ||. |.|..:...::...|         |.:.|  ..||.......:...|      .||::..:
Yeast   149 LDQMGFLREVDQWEITNRI---------VGNGTFGHVLITHNSKERDEDVCYHPENYAVKIIKLK 204

  Fly   184 TQSNDRGDTYMEAEVLRQLQSHPNIIELMYTVEDERY-------------MYTVLEHLDCNMQKV 235
            ....|:     ||.:|.:| .|||||::.:|..|...             :::.|...||...
Yeast   205 PNKFDK-----EARILLRL-DHPNIIKVYHTFCDRNNHLYIFQDLIPGGDLFSYLAKGDCLTS-- 261

  Fly   236 IQKRGILSEADARSVMRCTVSALAHMHQLQVIHRDIKPENLLVCSSSGKWNFKMVKVANFDLATY 300
                  :||.::..::...:.||.::|...::|||:|.:|:|:|:..   ....:.:|:|.:|..
Yeast   262 ------MSETESLLIVFQILQALNYLHDQDIVHRDLKLDNILLCTPE---PCTRIVLADFGIAKD 317

  Fly   301 YRGSK--LYVRCGTPCYMAPEM-----------------IAMSGYDYQVDSWSLGVTLFYMLCGK 346
            ...:|  ::...|||.|.|||:                 :...|||.:.|.|||||....||.|.
Yeast   318 LNSNKERMHTVVGTPEYCAPEVGFRANRKAYQSFSRAATLEQRGYDSKCDLWSLGVITHIMLTGI 382

  Fly   347 MPF------ASACKNSKEIYAAIMSGGPTYPKDMESVMSPEATQLIDGLLVSD 393
            .||      .|..:|:|       .|...:......::|..|...:..||.:|
Yeast   383 SPFYGDGSERSIIQNAK-------IGKLNFKLKQWDIVSDNAKSFVKDLLQTD 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10177	NP_651150.1	DCX	18..108	CDD:214711	6/44 (14%)
		S_TKc	164..409	CDD:214567	64/274 (23%)
MEK1	NP_014996.3	FHA_MEK1-like	24..123	CDD:438722	5/29 (17%)
		STKc_CAMK	160..443	CDD:270687	69/302 (23%)